Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 18 studies | 31% ± 13% | |
macrophage | 17 studies | 29% ± 16% | |
oligodendrocyte | 16 studies | 77% ± 19% | |
astrocyte | 13 studies | 36% ± 16% | |
microglial cell | 12 studies | 41% ± 14% | |
glutamatergic neuron | 10 studies | 47% ± 24% | |
fibroblast | 10 studies | 30% ± 15% | |
mast cell | 10 studies | 28% ± 11% | |
smooth muscle cell | 9 studies | 23% ± 8% | |
GABAergic neuron | 8 studies | 41% ± 20% | |
oligodendrocyte precursor cell | 8 studies | 28% ± 11% | |
myeloid cell | 8 studies | 23% ± 4% | |
pericyte | 7 studies | 23% ± 6% | |
plasma cell | 6 studies | 32% ± 11% | |
epithelial cell | 6 studies | 32% ± 10% | |
dendritic cell | 6 studies | 26% ± 5% | |
endothelial cell of lymphatic vessel | 6 studies | 34% ± 14% | |
neuron | 5 studies | 43% ± 24% | |
B cell | 5 studies | 23% ± 7% | |
CD8-positive, alpha-beta T cell | 5 studies | 18% ± 3% | |
hepatocyte | 5 studies | 54% ± 26% | |
monocyte | 5 studies | 25% ± 7% | |
interneuron | 4 studies | 44% ± 19% | |
retinal pigment epithelial cell | 4 studies | 36% ± 3% | |
adipocyte | 4 studies | 18% ± 3% | |
lymphocyte | 4 studies | 31% ± 15% | |
brush cell | 4 studies | 29% ± 9% | |
ionocyte | 3 studies | 35% ± 2% | |
classical monocyte | 3 studies | 20% ± 5% | |
conventional dendritic cell | 3 studies | 18% ± 0% | |
effector memory CD8-positive, alpha-beta T cell | 3 studies | 17% ± 2% | |
hematopoietic precursor cell | 3 studies | 21% ± 8% | |
plasmablast | 3 studies | 30% ± 16% | |
GABAergic interneuron | 3 studies | 22% ± 4% | |
CD4-positive, alpha-beta T cell | 3 studies | 23% ± 2% | |
non-classical monocyte | 3 studies | 22% ± 6% | |
T cell | 3 studies | 24% ± 3% | |
capillary endothelial cell | 3 studies | 18% ± 3% | |
natural killer cell | 3 studies | 21% ± 2% | |
transit amplifying cell | 3 studies | 32% ± 21% | |
plasmacytoid dendritic cell | 3 studies | 19% ± 3% | |
renal alpha-intercalated cell | 3 studies | 26% ± 5% | |
renal principal cell | 3 studies | 20% ± 4% | |
regulatory T cell | 3 studies | 18% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 100% | 1289.13 | 578 / 578 | 99% | 18.52 | 1145 / 1155 |
esophagus | 98% | 775.43 | 1423 / 1445 | 100% | 22.29 | 183 / 183 |
kidney | 100% | 803.64 | 89 / 89 | 98% | 25.04 | 885 / 901 |
breast | 100% | 1125.14 | 459 / 459 | 98% | 22.48 | 1098 / 1118 |
stomach | 99% | 952.48 | 357 / 359 | 99% | 21.32 | 282 / 286 |
liver | 99% | 1056.95 | 223 / 226 | 99% | 23.89 | 403 / 406 |
uterus | 100% | 1055.76 | 170 / 170 | 98% | 16.23 | 448 / 459 |
intestine | 99% | 1189.08 | 961 / 966 | 98% | 20.20 | 516 / 527 |
bladder | 100% | 1133.10 | 21 / 21 | 97% | 15.44 | 487 / 504 |
pancreas | 99% | 1313.76 | 326 / 328 | 97% | 18.29 | 173 / 178 |
thymus | 100% | 867.11 | 650 / 653 | 97% | 13.16 | 585 / 605 |
prostate | 95% | 500.34 | 233 / 245 | 95% | 15.02 | 476 / 502 |
skin | 100% | 2028.95 | 1805 / 1809 | 84% | 9.51 | 398 / 472 |
adrenal gland | 100% | 1997.17 | 257 / 258 | 79% | 15.37 | 182 / 230 |
ovary | 100% | 921.87 | 180 / 180 | 70% | 5.47 | 302 / 430 |
brain | 75% | 589.08 | 1979 / 2642 | 95% | 11.77 | 670 / 705 |
spleen | 100% | 842.94 | 241 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 1652.06 | 1334 / 1335 | 0% | 0 | 0 / 0 |
adipose | 100% | 1087.62 | 1203 / 1204 | 0% | 0 | 0 / 0 |
muscle | 99% | 687.24 | 792 / 803 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 98% | 16.77 | 44 / 45 |
lymph node | 0% | 0 | 0 / 0 | 93% | 15.86 | 27 / 29 |
peripheral blood | 80% | 678.29 | 742 / 929 | 0% | 0 | 0 / 0 |
heart | 68% | 255.60 | 582 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 41% | 3.08 | 33 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0001701 | Biological process | in utero embryonic development |
GO_0050769 | Biological process | positive regulation of neurogenesis |
GO_0001889 | Biological process | liver development |
GO_0007033 | Biological process | vacuole organization |
GO_0007005 | Biological process | mitochondrion organization |
GO_0060042 | Biological process | retina morphogenesis in camera-type eye |
GO_0019082 | Biological process | viral protein processing |
GO_0006491 | Biological process | N-glycan processing |
GO_0006013 | Biological process | mannose metabolic process |
GO_0006517 | Biological process | protein deglycosylation |
GO_0006486 | Biological process | protein glycosylation |
GO_0048286 | Biological process | lung alveolus development |
GO_0007585 | Biological process | respiratory gaseous exchange by respiratory system |
GO_0005801 | Cellular component | cis-Golgi network |
GO_0016020 | Cellular component | membrane |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005797 | Cellular component | Golgi medial cisterna |
GO_0000139 | Cellular component | Golgi membrane |
GO_0042803 | Molecular function | protein homodimerization activity |
GO_0004559 | Molecular function | alpha-mannosidase activity |
GO_0030246 | Molecular function | carbohydrate binding |
GO_0046872 | Molecular function | metal ion binding |
GO_0004572 | Molecular function | mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity |
GO_0016799 | Molecular function | hydrolase activity, hydrolyzing N-glycosyl compounds |
Gene name | MAN2A1 |
Protein name | Alpha-mannosidase (EC 3.2.1.-) Alpha-mannosidase 2 (EC 3.2.1.114) (Golgi alpha-mannosidase II) (AMan II) (Man II) (Mannosidase alpha class 2A member 1) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase) MAN2A1 protein |
Synonyms | MANA2 |
Description | FUNCTION: Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway. . |
Accessions | Q16706 A5PKX5 Q49A69 ENST00000261483.5 |