Name | Number of supported studies | Average coverage | |
---|---|---|---|
macrophage | 47 studies | 50% ± 19% | |
classical monocyte | 27 studies | 49% ± 16% | |
non-classical monocyte | 25 studies | 63% ± 14% | |
monocyte | 21 studies | 40% ± 15% | |
fibroblast | 20 studies | 29% ± 13% | |
conventional dendritic cell | 16 studies | 26% ± 9% | |
myeloid cell | 13 studies | 44% ± 15% | |
dendritic cell | 12 studies | 30% ± 18% | |
alveolar macrophage | 7 studies | 27% ± 3% | |
connective tissue cell | 7 studies | 28% ± 8% | |
mononuclear phagocyte | 6 studies | 49% ± 14% | |
leukocyte | 6 studies | 28% ± 7% | |
smooth muscle cell | 6 studies | 30% ± 7% | |
intermediate monocyte | 6 studies | 58% ± 20% | |
neutrophil | 5 studies | 37% ± 18% | |
endothelial cell | 5 studies | 26% ± 10% | |
microglial cell | 5 studies | 41% ± 21% | |
pancreatic A cell | 4 studies | 57% ± 22% | |
type B pancreatic cell | 4 studies | 47% ± 22% | |
podocyte | 4 studies | 81% ± 17% | |
myofibroblast cell | 4 studies | 20% ± 3% | |
basal cell | 4 studies | 31% ± 19% | |
inflammatory macrophage | 4 studies | 51% ± 9% | |
pericyte | 4 studies | 23% ± 5% | |
glomerular endothelial cell | 3 studies | 32% ± 8% | |
epithelial cell | 3 studies | 24% ± 8% | |
adventitial cell | 3 studies | 20% ± 5% | |
tissue-resident macrophage | 3 studies | 63% ± 17% | |
GABAergic neuron | 3 studies | 26% ± 9% | |
interneuron | 3 studies | 19% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 4865.52 | 459 / 459 | 99% | 71.16 | 1103 / 1118 |
thymus | 100% | 3604.35 | 652 / 653 | 98% | 51.36 | 591 / 605 |
lung | 98% | 3651.87 | 568 / 578 | 95% | 54.57 | 1092 / 1155 |
kidney | 96% | 2399.89 | 85 / 89 | 86% | 42.09 | 771 / 901 |
esophagus | 92% | 2817.26 | 1336 / 1445 | 88% | 77.48 | 161 / 183 |
prostate | 81% | 1351.06 | 198 / 245 | 94% | 27.81 | 473 / 502 |
bladder | 95% | 1670.86 | 20 / 21 | 74% | 30.72 | 373 / 504 |
skin | 78% | 8013.49 | 1413 / 1809 | 89% | 44.77 | 418 / 472 |
liver | 88% | 2361.59 | 199 / 226 | 77% | 26.53 | 312 / 406 |
adrenal gland | 97% | 2219.49 | 250 / 258 | 67% | 28.40 | 153 / 230 |
uterus | 71% | 1162.67 | 121 / 170 | 90% | 65.65 | 413 / 459 |
pancreas | 62% | 832.26 | 204 / 328 | 93% | 79.04 | 166 / 178 |
ovary | 49% | 722.38 | 89 / 180 | 96% | 57.28 | 412 / 430 |
intestine | 86% | 1516.02 | 833 / 966 | 56% | 20.24 | 293 / 527 |
stomach | 54% | 910.27 | 194 / 359 | 72% | 29.42 | 205 / 286 |
brain | 25% | 314.64 | 651 / 2642 | 98% | 70.97 | 691 / 705 |
adipose | 100% | 5504.94 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 70.01 | 29 / 29 |
spleen | 100% | 15879.86 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 96% | 75.75 | 43 / 45 |
blood vessel | 94% | 2633.76 | 1258 / 1335 | 0% | 0 | 0 / 0 |
peripheral blood | 74% | 2062.17 | 692 / 929 | 0% | 0 | 0 / 0 |
muscle | 67% | 1306.93 | 540 / 803 | 0% | 0 | 0 / 0 |
heart | 55% | 866.21 | 470 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 31% | 6.45 | 25 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0030216 | Biological process | keratinocyte differentiation |
GO_0045671 | Biological process | negative regulation of osteoclast differentiation |
GO_0021599 | Biological process | abducens nerve formation |
GO_0045637 | Biological process | regulation of myeloid cell differentiation |
GO_0045647 | Biological process | negative regulation of erythrocyte differentiation |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0021571 | Biological process | rhombomere 5 development |
GO_0016485 | Biological process | protein processing |
GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
GO_0033077 | Biological process | T cell differentiation in thymus |
GO_1903575 | Biological process | cornified envelope assembly |
GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
GO_0048538 | Biological process | thymus development |
GO_0007379 | Biological process | segment specification |
GO_0006355 | Biological process | regulation of DNA-templated transcription |
GO_0042472 | Biological process | inner ear morphogenesis |
GO_0035284 | Biological process | brain segmentation |
GO_0021572 | Biological process | rhombomere 6 development |
GO_0007423 | Biological process | sensory organ development |
GO_0140467 | Biological process | integrated stress response signaling |
GO_0045444 | Biological process | fat cell differentiation |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0007585 | Biological process | respiratory gaseous exchange by respiratory system |
GO_0090575 | Cellular component | RNA polymerase II transcription regulator complex |
GO_0000785 | Cellular component | chromatin |
GO_0005634 | Cellular component | nucleus |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
GO_0043565 | Molecular function | sequence-specific DNA binding |
GO_0044877 | Molecular function | protein-containing complex binding |
GO_0042802 | Molecular function | identical protein binding |
GO_0005515 | Molecular function | protein binding |
Gene name | MAFB |
Protein name | Alternative protein MAFB Transcription factor MafB (Maf-B) (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B) |
Synonyms | KRML |
Description | FUNCTION: Acts as a transcriptional activator or repressor . Plays a pivotal role in regulating lineage-specific hematopoiesis by repressing ETS1-mediated transcription of erythroid-specific genes in myeloid cells. Required for monocytic, macrophage, osteoclast, podocyte and islet beta cell differentiation. Involved in renal tubule survival and F4/80 maturation. Activates the insulin and glucagon promoters. Together with PAX6, transactivates weakly the glucagon gene promoter through the G1 element. SUMO modification controls its transcriptional activity and ability to specify macrophage fate. Binds element G1 on the glucagon promoter (By similarity). Involved either as an oncogene or as a tumor suppressor, depending on the cell context. Required for the transcriptional activation of HOXB3 in the rhombomere r5 in the hindbrain (By similarity). . |
Accessions | Q9Y5Q3 ENST00000373313.3 L8ECC4 |