KLF7 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007409Biological processaxonogenesis
GO_0061179Biological processnegative regulation of insulin secretion involved in cellular response to glucose stimulus
GO_1904178Biological processnegative regulation of adipose tissue development
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0045604Biological processregulation of epidermal cell differentiation
GO_0048813Biological processdendrite morphogenesis
GO_0042593Biological processglucose homeostasis
GO_0007411Biological processaxon guidance
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0008270Molecular functionzinc ion binding

IV. Literature review

[source]
Gene nameKLF7
Protein nameKruppel like factor 7
Uncharacterized protein KLF7
Krueppel-like factor 7 (Ubiquitous krueppel-like factor)
KLF transcription factor 7
Alternative protein KLF7
SynonymsUKLF
DescriptionFUNCTION: Transcriptional factor . Plays a critical role in neuronal morphogenesis and survival of sensory neurons (By similarity). Represses the corneal epithelium differentiation . Acts also as a metabolic regulator, by modulating insulin sensitivity in pancreatic beta cells and skeletal muscle cells . Inhibits transcriptional inducers of adipogenesis and has a repressive role in the expression of several adipokines, including leptin . .

AccessionsENST00000426163.5
A0A994J401
ENST00000457962.5
A0A994J3U4
A0A994J6Y4
O75840
L8E9A5
ENST00000703736.1
ENST00000703735.1
Q4ZG79
ENST00000458272.2 [O75840-5]
ENST00000435602.2
C9JX20
E9PHC9
Q53TP3
ENST00000309446.11 [O75840-1]
ENST00000703734.1 [O75840-3]
E7EUU0
E7EQY2
ENST00000451244.1
ENST00000435602.2 [O75840-4]
ENST00000423015.5 [O75840-3]
ENST00000421199.5 [O75840-2]
ENST00000703689.1