Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 39 studies | 32% ± 14% | |
astrocyte | 14 studies | 34% ± 16% | |
oligodendrocyte | 12 studies | 33% ± 10% | |
capillary endothelial cell | 11 studies | 28% ± 9% | |
macrophage | 11 studies | 34% ± 14% | |
oligodendrocyte precursor cell | 10 studies | 29% ± 12% | |
glutamatergic neuron | 9 studies | 37% ± 22% | |
microglial cell | 9 studies | 28% ± 11% | |
endothelial cell of vascular tree | 9 studies | 29% ± 14% | |
fibroblast | 8 studies | 25% ± 10% | |
myeloid cell | 7 studies | 30% ± 7% | |
GABAergic neuron | 7 studies | 36% ± 13% | |
pericyte | 6 studies | 28% ± 13% | |
smooth muscle cell | 6 studies | 24% ± 6% | |
endothelial cell of artery | 6 studies | 23% ± 5% | |
vein endothelial cell | 6 studies | 37% ± 18% | |
endothelial cell of lymphatic vessel | 6 studies | 28% ± 7% | |
type I pneumocyte | 6 studies | 25% ± 7% | |
neuron | 5 studies | 46% ± 14% | |
retinal ganglion cell | 5 studies | 45% ± 18% | |
dendritic cell | 5 studies | 17% ± 2% | |
monocyte | 5 studies | 26% ± 6% | |
non-classical monocyte | 4 studies | 24% ± 7% | |
epithelial cell | 4 studies | 23% ± 7% | |
interneuron | 4 studies | 34% ± 12% | |
cardiac muscle cell | 4 studies | 19% ± 3% | |
glomerular endothelial cell | 3 studies | 34% ± 3% | |
granule cell | 3 studies | 34% ± 5% | |
adipocyte | 3 studies | 25% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 100% | 5141.39 | 578 / 578 | 97% | 14.97 | 1116 / 1155 |
brain | 97% | 2015.67 | 2570 / 2642 | 99% | 15.36 | 699 / 705 |
kidney | 100% | 2430.70 | 89 / 89 | 95% | 17.85 | 852 / 901 |
esophagus | 100% | 3347.74 | 1441 / 1445 | 94% | 22.79 | 172 / 183 |
breast | 100% | 4856.34 | 459 / 459 | 94% | 13.23 | 1047 / 1118 |
thymus | 100% | 2841.77 | 652 / 653 | 93% | 9.35 | 565 / 605 |
ovary | 100% | 2954.22 | 180 / 180 | 92% | 9.00 | 396 / 430 |
uterus | 100% | 4846.65 | 170 / 170 | 92% | 11.56 | 422 / 459 |
stomach | 100% | 2403.56 | 358 / 359 | 90% | 10.42 | 258 / 286 |
bladder | 100% | 3273.90 | 21 / 21 | 88% | 10.00 | 446 / 504 |
prostate | 99% | 2203.76 | 243 / 245 | 87% | 7.31 | 437 / 502 |
adrenal gland | 100% | 2282.98 | 257 / 258 | 87% | 9.79 | 199 / 230 |
skin | 99% | 2776.24 | 1784 / 1809 | 86% | 8.59 | 408 / 472 |
intestine | 98% | 3355.54 | 947 / 966 | 85% | 9.00 | 447 / 527 |
pancreas | 63% | 639.26 | 205 / 328 | 97% | 16.21 | 172 / 178 |
liver | 79% | 794.16 | 179 / 226 | 32% | 2.72 | 128 / 406 |
adipose | 100% | 5727.96 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 4392.00 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 3067.03 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 4.13 | 1 / 1 |
heart | 99% | 2116.33 | 855 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 95% | 2600.61 | 878 / 929 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 93% | 14.00 | 42 / 45 |
muscle | 75% | 787.22 | 606 / 803 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 48% | 3.29 | 14 / 29 |
eye | 0% | 0 | 0 / 0 | 44% | 2.27 | 35 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007409 | Biological process | axonogenesis |
GO_0061179 | Biological process | negative regulation of insulin secretion involved in cellular response to glucose stimulus |
GO_1904178 | Biological process | negative regulation of adipose tissue development |
GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
GO_0045604 | Biological process | regulation of epidermal cell differentiation |
GO_0048813 | Biological process | dendrite morphogenesis |
GO_0042593 | Biological process | glucose homeostasis |
GO_0007411 | Biological process | axon guidance |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0000785 | Cellular component | chromatin |
GO_0005634 | Cellular component | nucleus |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
GO_0008270 | Molecular function | zinc ion binding |
Gene name | KLF7 |
Protein name | Kruppel like factor 7 Uncharacterized protein KLF7 Krueppel-like factor 7 (Ubiquitous krueppel-like factor) KLF transcription factor 7 Alternative protein KLF7 |
Synonyms | UKLF |
Description | FUNCTION: Transcriptional factor . Plays a critical role in neuronal morphogenesis and survival of sensory neurons (By similarity). Represses the corneal epithelium differentiation . Acts also as a metabolic regulator, by modulating insulin sensitivity in pancreatic beta cells and skeletal muscle cells . Inhibits transcriptional inducers of adipogenesis and has a repressive role in the expression of several adipokines, including leptin . . |
Accessions | ENST00000426163.5 A0A994J401 ENST00000457962.5 A0A994J3U4 A0A994J6Y4 O75840 L8E9A5 ENST00000703736.1 ENST00000703735.1 Q4ZG79 ENST00000458272.2 [O75840-5] ENST00000435602.2 C9JX20 E9PHC9 Q53TP3 ENST00000309446.11 [O75840-1] ENST00000703734.1 [O75840-3] E7EUU0 E7EQY2 ENST00000451244.1 ENST00000435602.2 [O75840-4] ENST00000423015.5 [O75840-3] ENST00000421199.5 [O75840-2] ENST00000703689.1 |