Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 22 studies | 50% ± 18% | |
astrocyte | 16 studies | 50% ± 21% | |
smooth muscle cell | 12 studies | 44% ± 18% | |
pericyte | 12 studies | 40% ± 14% | |
GABAergic neuron | 11 studies | 68% ± 27% | |
glutamatergic neuron | 11 studies | 86% ± 13% | |
oligodendrocyte precursor cell | 11 studies | 38% ± 15% | |
endothelial cell of lymphatic vessel | 10 studies | 67% ± 22% | |
fibroblast | 8 studies | 29% ± 8% | |
neuron | 7 studies | 54% ± 21% | |
adipocyte | 7 studies | 29% ± 10% | |
oligodendrocyte | 7 studies | 29% ± 18% | |
interneuron | 6 studies | 74% ± 20% | |
microglial cell | 6 studies | 38% ± 19% | |
epithelial cell | 5 studies | 26% ± 7% | |
capillary endothelial cell | 5 studies | 34% ± 21% | |
cardiac muscle cell | 5 studies | 48% ± 15% | |
mesothelial cell | 5 studies | 44% ± 19% | |
vein endothelial cell | 5 studies | 44% ± 17% | |
ciliated cell | 4 studies | 21% ± 8% | |
endothelial cell of sinusoid | 3 studies | 53% ± 5% | |
hepatic stellate cell | 3 studies | 47% ± 15% | |
GABAergic interneuron | 3 studies | 76% ± 1% | |
retinal bipolar neuron | 3 studies | 39% ± 16% | |
GABAergic amacrine cell | 3 studies | 51% ± 20% | |
Mueller cell | 3 studies | 36% ± 13% | |
retinal ganglion cell | 3 studies | 51% ± 28% | |
rod bipolar cell | 3 studies | 63% ± 21% | |
endothelial cell of vascular tree | 3 studies | 47% ± 11% | |
connective tissue cell | 3 studies | 27% ± 5% | |
ependymal cell | 3 studies | 43% ± 8% | |
muscle cell | 3 studies | 47% ± 36% | |
brush cell | 3 studies | 34% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
stomach | 100% | 3137.36 | 359 / 359 | 99% | 6.21 | 282 / 286 |
brain | 85% | 4810.19 | 2257 / 2642 | 99% | 7.76 | 700 / 705 |
liver | 96% | 1550.82 | 218 / 226 | 88% | 2.81 | 358 / 406 |
thymus | 99% | 2222.58 | 647 / 653 | 84% | 2.91 | 511 / 605 |
esophagus | 99% | 2001.36 | 1433 / 1445 | 82% | 3.85 | 150 / 183 |
intestine | 83% | 1657.32 | 804 / 966 | 98% | 5.61 | 514 / 527 |
kidney | 93% | 1518.58 | 83 / 89 | 85% | 3.31 | 767 / 901 |
breast | 100% | 3760.86 | 457 / 459 | 78% | 2.25 | 870 / 1118 |
adrenal gland | 100% | 2610.28 | 258 / 258 | 74% | 2.29 | 171 / 230 |
pancreas | 82% | 1210.41 | 268 / 328 | 92% | 4.62 | 164 / 178 |
prostate | 83% | 1334.78 | 203 / 245 | 84% | 1.96 | 420 / 502 |
lung | 98% | 2092.72 | 566 / 578 | 65% | 1.98 | 751 / 1155 |
ovary | 84% | 1425.65 | 151 / 180 | 76% | 2.61 | 327 / 430 |
uterus | 100% | 4130.11 | 170 / 170 | 59% | 1.83 | 270 / 459 |
bladder | 76% | 1109.43 | 16 / 21 | 62% | 2.63 | 311 / 504 |
skin | 53% | 692.50 | 967 / 1809 | 56% | 2.10 | 264 / 472 |
adipose | 100% | 4003.91 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 10598.48 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 4393.21 | 241 / 241 | 0% | 0 | 0 / 0 |
muscle | 99% | 3048.81 | 797 / 803 | 0% | 0 | 0 / 0 |
heart | 96% | 2555.59 | 824 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 44% | 1.01 | 20 / 45 |
lymph node | 0% | 0 | 0 / 0 | 7% | 0.18 | 2 / 29 |
peripheral blood | 6% | 84.69 | 58 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 4% | 0.05 | 3 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0048013 | Biological process | ephrin receptor signaling pathway |
GO_0007165 | Biological process | signal transduction |
GO_0051056 | Biological process | regulation of small GTPase mediated signal transduction |
GO_0016192 | Biological process | vesicle-mediated transport |
GO_0035556 | Biological process | intracellular signal transduction |
GO_0006468 | Biological process | protein phosphorylation |
GO_0007399 | Biological process | nervous system development |
GO_0007411 | Biological process | axon guidance |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005654 | Cellular component | nucleoplasm |
GO_0019898 | Cellular component | extrinsic component of membrane |
GO_0015629 | Cellular component | actin cytoskeleton |
GO_0005829 | Cellular component | cytosol |
GO_0014069 | Cellular component | postsynaptic density |
GO_0005737 | Cellular component | cytoplasm |
GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
GO_0106310 | Molecular function | protein serine kinase activity |
GO_0004674 | Molecular function | protein serine/threonine kinase activity |
GO_0046872 | Molecular function | metal ion binding |
GO_0005524 | Molecular function | ATP binding |
GO_0005515 | Molecular function | protein binding |
Gene name | KALRN |
Protein name | Kalirin RhoGEF kinase HCG2022551, isoform CRA_f (Kalirin RhoGEF kinase) non-specific serine/threonine protein kinase (EC 2.7.11.1) Kalirin Kalirin (EC 2.7.11.1) (Huntingtin-associated protein-interacting protein) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain) HCG2022551, isoform CRA_j (Kalirin RhoGEF kinase) |
Synonyms | DUET HAPIP DUO TRAD hCG_2022551 |
Description | FUNCTION: Promotes the exchange of GDP by GTP. Activates specific Rho GTPase family members, thereby inducing various signaling mechanisms that regulate neuronal shape, growth, and plasticity, through their effects on the actin cytoskeleton. Induces lamellipodia independent of its GEF activity. . |
Accessions | O60229 ENST00000684360.1 A0A804HIY9 ENST00000360013.7 [O60229-1] A0A804HI91 A0A804HKJ7 A0A804HII1 ENST00000354186.8 ENST00000684382.1 ENST00000683428.1 A0A0D9SGH1 C9J1B4 ENST00000683356.1 ENST00000682540.1 H7BXZ5 A0A804HJ49 A0A1S5UZ29 A0A804HLF3 H7C1X7 ENST00000291478.9 [O60229-4] ENST00000682625.1 A0A804HIN3 ENST00000682363.1 ENST00000682861.1 ENST00000682277.1 A0A804HKU9 A0A804HJ74 A0A804HI42 ENST00000439170.2 ENST00000682890.1 ENST00000683571.1 A0A804HJC5 C9IZQ6 A0A804HIP9 ENST00000684374.1 ENST00000682575.1 A0A804HJZ3 ENST00000682506.1 ENST00000682636.1 ENST00000522553.6 A0A804HLC8 ENST00000684276.1 A0A804HLI0 ENST00000682695.1 ENST00000682290.1 A0A804HIK8 A0A804HI83 ENST00000683280.1 A0A804HJX0 ENST00000682674.1 ENST00000454902.1 ENST00000240874.7 [O60229-2] ENST00000460856.5 A0A804HHT5 A0A804HKT9 ENST00000684186.1 ENST00000683146.1 ENST00000483658.2 |