Name | Number of supported studies | Average coverage | |
---|---|---|---|
pericyte | 9 studies | 22% ± 4% | |
fibroblast | 8 studies | 21% ± 3% | |
smooth muscle cell | 8 studies | 23% ± 3% | |
type I pneumocyte | 7 studies | 22% ± 6% | |
endothelial cell | 6 studies | 24% ± 6% | |
adipocyte | 6 studies | 24% ± 7% | |
CD16-negative, CD56-bright natural killer cell, human | 5 studies | 19% ± 2% | |
ciliated cell | 5 studies | 28% ± 9% | |
renal alpha-intercalated cell | 4 studies | 28% ± 3% | |
ionocyte | 3 studies | 25% ± 3% | |
epithelial cell | 3 studies | 30% ± 9% | |
CD16-positive, CD56-dim natural killer cell, human | 3 studies | 17% ± 1% | |
natural killer cell | 3 studies | 17% ± 2% | |
muscle cell | 3 studies | 19% ± 3% | |
GABAergic neuron | 3 studies | 43% ± 9% | |
glutamatergic neuron | 3 studies | 49% ± 11% | |
astrocyte | 3 studies | 27% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
adrenal gland | 100% | 3782.79 | 258 / 258 | 100% | 19.23 | 230 / 230 |
thymus | 100% | 6969.54 | 653 / 653 | 100% | 36.49 | 605 / 605 |
kidney | 100% | 4345.45 | 89 / 89 | 100% | 23.66 | 899 / 901 |
prostate | 100% | 4188.27 | 245 / 245 | 99% | 18.34 | 499 / 502 |
breast | 100% | 4823.11 | 459 / 459 | 99% | 12.27 | 1106 / 1118 |
pancreas | 100% | 5505.60 | 328 / 328 | 99% | 14.06 | 176 / 178 |
ovary | 100% | 4407.05 | 180 / 180 | 99% | 8.90 | 424 / 430 |
skin | 100% | 2992.92 | 1808 / 1809 | 96% | 14.04 | 452 / 472 |
brain | 96% | 2007.70 | 2531 / 2642 | 100% | 19.06 | 704 / 705 |
stomach | 100% | 3579.87 | 359 / 359 | 95% | 9.37 | 273 / 286 |
lung | 100% | 3702.13 | 576 / 578 | 96% | 10.15 | 1104 / 1155 |
uterus | 100% | 3114.56 | 170 / 170 | 95% | 10.19 | 436 / 459 |
intestine | 98% | 2990.14 | 950 / 966 | 92% | 7.69 | 486 / 527 |
esophagus | 98% | 3555.55 | 1410 / 1445 | 93% | 9.75 | 170 / 183 |
bladder | 100% | 4484.76 | 21 / 21 | 90% | 7.46 | 454 / 504 |
liver | 97% | 1332.58 | 219 / 226 | 91% | 7.37 | 371 / 406 |
adipose | 100% | 5018.91 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 5486.64 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 10.58 | 29 / 29 |
spleen | 100% | 2905.51 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 7.50 | 1 / 1 |
muscle | 99% | 1948.13 | 795 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 99% | 11.41 | 79 / 80 |
heart | 97% | 2549.11 | 838 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 93% | 10.18 | 42 / 45 |
peripheral blood | 84% | 1622.81 | 777 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0001558 | Biological process | regulation of cell growth |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0090090 | Biological process | negative regulation of canonical Wnt signaling pathway |
GO_0006338 | Biological process | chromatin remodeling |
GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
GO_0006355 | Biological process | regulation of DNA-templated transcription |
GO_2000278 | Biological process | regulation of DNA biosynthetic process |
GO_0006915 | Biological process | apoptotic process |
GO_2000134 | Biological process | negative regulation of G1/S transition of mitotic cell cycle |
GO_0006275 | Biological process | regulation of DNA replication |
GO_0051726 | Biological process | regulation of cell cycle |
GO_0030308 | Biological process | negative regulation of cell growth |
GO_0005886 | Cellular component | plasma membrane |
GO_0016607 | Cellular component | nuclear speck |
GO_0005813 | Cellular component | centrosome |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005737 | Cellular component | cytoplasm |
GO_0036064 | Cellular component | ciliary basal body |
GO_0000123 | Cellular component | histone acetyltransferase complex |
GO_0005634 | Cellular component | nucleus |
GO_0043997 | Molecular function | histone H4K12 acetyltransferase activity |
GO_0036408 | Molecular function | histone H3K14 acetyltransferase activity |
GO_0046972 | Molecular function | histone H4K16 acetyltransferase activity |
GO_0043996 | Molecular function | histone H4K8 acetyltransferase activity |
GO_0043995 | Molecular function | histone H4K5 acetyltransferase activity |
GO_0046872 | Molecular function | metal ion binding |
GO_0003713 | Molecular function | transcription coactivator activity |
GO_0005515 | Molecular function | protein binding |
Gene name | JADE1 |
Protein name | Jade family PHD finger 1 Protein Jade-1 (Jade family PHD finger protein 1) (PHD finger protein 17) |
Synonyms | PHF17 KIAA1807 |
Description | FUNCTION: Scaffold subunit of some HBO1 complexes, which have a histone H4 acetyltransferase activity . Plays a key role in HBO1 complex by directing KAT7/HBO1 specificity towards histone H4 acetylation (H4K5ac, H4K8ac and H4K12ac), regulating DNA replication initiation, regulating DNA replication initiation . May also promote acetylation of nucleosomal histone H4 by KAT5 . Promotes apoptosis . May act as a renal tumor suppressor . Negatively regulates canonical Wnt signaling; at least in part, cooperates with NPHP4 in this function . . |
Accessions | D6RAS5 ENST00000611140.4 [Q6IE81-1] ENST00000503785.5 ENST00000504089.5 ENST00000507833.5 D6RE74 ENST00000610919.4 [Q6IE81-1] D6RC05 ENST00000511925.5 ENST00000226319.11 [Q6IE81-1] ENST00000511647.5 [Q6IE81-3] ENST00000512960.5 [Q6IE81-1] D6RCS1 ENST00000508997.1 ENST00000452328.6 [Q6IE81-2] ENST00000514740.1 ENST00000413543.6 [Q6IE81-3] D6RGE7 D6RFK0 Q6IE81 ENST00000510308.5 D6RBB3 |