Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 13 studies | 27% ± 13% | |
glutamatergic neuron | 7 studies | 40% ± 26% | |
microglial cell | 7 studies | 27% ± 9% | |
plasmacytoid dendritic cell | 7 studies | 20% ± 6% | |
fibroblast | 7 studies | 22% ± 9% | |
adipocyte | 7 studies | 23% ± 4% | |
GABAergic neuron | 7 studies | 35% ± 20% | |
astrocyte | 7 studies | 30% ± 11% | |
oligodendrocyte | 7 studies | 24% ± 7% | |
macrophage | 7 studies | 25% ± 6% | |
natural killer cell | 6 studies | 19% ± 5% | |
epithelial cell | 6 studies | 33% ± 11% | |
B cell | 5 studies | 23% ± 6% | |
dendritic cell | 5 studies | 29% ± 17% | |
basal cell | 5 studies | 26% ± 11% | |
interneuron | 5 studies | 36% ± 23% | |
CD16-positive, CD56-dim natural killer cell, human | 4 studies | 20% ± 4% | |
neuron | 4 studies | 31% ± 8% | |
myeloid cell | 4 studies | 22% ± 3% | |
oligodendrocyte precursor cell | 4 studies | 33% ± 9% | |
monocyte | 4 studies | 21% ± 3% | |
CD4-positive, alpha-beta T cell | 3 studies | 22% ± 5% | |
CD8-positive, alpha-beta T cell | 3 studies | 21% ± 5% | |
classical monocyte | 3 studies | 27% ± 6% | |
hematopoietic precursor cell | 3 studies | 31% ± 14% | |
non-classical monocyte | 3 studies | 29% ± 12% | |
GABAergic interneuron | 3 studies | 17% ± 1% | |
retina horizontal cell | 3 studies | 25% ± 1% | |
ciliated cell | 3 studies | 25% ± 3% | |
lymphocyte | 3 studies | 20% ± 3% | |
club cell | 3 studies | 20% ± 4% | |
alveolar macrophage | 3 studies | 22% ± 8% | |
endothelial cell of lymphatic vessel | 3 studies | 22% ± 3% | |
goblet cell | 3 studies | 29% ± 14% | |
transit amplifying cell | 3 studies | 28% ± 16% | |
mast cell | 3 studies | 20% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 2902.91 | 1445 / 1445 | 100% | 23.70 | 183 / 183 |
lung | 100% | 3204.89 | 577 / 578 | 100% | 19.50 | 1154 / 1155 |
breast | 100% | 3739.86 | 459 / 459 | 100% | 22.26 | 1115 / 1118 |
prostate | 100% | 3264.70 | 245 / 245 | 100% | 19.51 | 500 / 502 |
ovary | 100% | 4049.08 | 180 / 180 | 100% | 12.95 | 428 / 430 |
bladder | 100% | 3325.67 | 21 / 21 | 99% | 15.19 | 501 / 504 |
thymus | 100% | 3776.24 | 653 / 653 | 99% | 19.12 | 600 / 605 |
stomach | 100% | 2466.76 | 359 / 359 | 99% | 17.34 | 282 / 286 |
intestine | 100% | 3412.40 | 966 / 966 | 98% | 16.58 | 519 / 527 |
uterus | 100% | 3960.55 | 170 / 170 | 98% | 16.95 | 452 / 459 |
brain | 98% | 1929.58 | 2601 / 2642 | 100% | 17.57 | 705 / 705 |
kidney | 100% | 2287.79 | 89 / 89 | 98% | 17.77 | 887 / 901 |
pancreas | 99% | 1807.12 | 326 / 328 | 99% | 14.27 | 176 / 178 |
adrenal gland | 100% | 7801.55 | 258 / 258 | 96% | 12.00 | 221 / 230 |
skin | 100% | 3994.87 | 1809 / 1809 | 95% | 18.59 | 449 / 472 |
liver | 100% | 1971.93 | 226 / 226 | 95% | 9.99 | 385 / 406 |
adipose | 100% | 3686.80 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 2702.58 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 15.22 | 29 / 29 |
muscle | 100% | 3295.37 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 3782.37 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 6.94 | 1 / 1 |
tonsil | 0% | 0 | 0 / 0 | 98% | 16.70 | 44 / 45 |
heart | 96% | 1707.19 | 828 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 81% | 2255.09 | 757 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 70% | 6.49 | 56 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006101 | Biological process | citrate metabolic process |
GO_0009791 | Biological process | post-embryonic development |
GO_0030316 | Biological process | osteoclast differentiation |
GO_0060586 | Biological process | multicellular organismal-level iron ion homeostasis |
GO_0048255 | Biological process | mRNA stabilization |
GO_0051649 | Biological process | establishment of localization in cell |
GO_0006417 | Biological process | regulation of translation |
GO_0034101 | Biological process | erythrocyte homeostasis |
GO_0006879 | Biological process | intracellular iron ion homeostasis |
GO_0050892 | Biological process | intestinal absorption |
GO_0006099 | Biological process | tricarboxylic acid cycle |
GO_0006782 | Biological process | protoporphyrinogen IX biosynthetic process |
GO_0005739 | Cellular component | mitochondrion |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0003994 | Molecular function | aconitate hydratase activity |
GO_0046872 | Molecular function | metal ion binding |
GO_0003723 | Molecular function | RNA binding |
GO_0030350 | Molecular function | iron-responsive element binding |
GO_0005515 | Molecular function | protein binding |
GO_0051539 | Molecular function | 4 iron, 4 sulfur cluster binding |
Gene name | IREB2 |
Protein name | Iron responsive element binding protein 2 Iron-responsive element-binding protein 2 (IRE-BP 2) (Iron regulatory protein 2) (IRP2) |
Synonyms | |
Description | FUNCTION: RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA. . |
Accessions | ENST00000560440.5 [P48200-2] ENST00000559091.1 ENST00000560840.5 H0YLE0 H0YMA8 ENST00000558570.5 ENST00000559215.5 H0YL48 H0YN46 H0YNL8 ENST00000258886.13 [P48200-1] P48200 ENST00000558525.5 |