IRAG2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006997Biological processnucleus organization
GO_0002376Biological processimmune system process
GO_0006903Biological processvesicle targeting
GO_0006906Biological processvesicle fusion
GO_0007338Biological processsingle fertilization
GO_0005813Cellular componentcentrosome
GO_0035577Cellular componentazurophil granule membrane
GO_0005694Cellular componentchromosome
GO_0005886Cellular componentplasma membrane
GO_0000922Cellular componentspindle pole
GO_0005635Cellular componentnuclear envelope
GO_0016020Cellular componentmembrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0008017Molecular functionmicrotubule binding

IV. Literature review

[source]
Gene nameIRAG2
Protein nameInositol 1,4,5-triphosphate receptor associated 2 (Lymphoid-restricted membrane protein) (Protein Jaw1) [Cleaved into: Processed inositol 1,4,5-triphosphate receptor associated 2]
Inositol 1,4,5-triphosphate receptor-associated 2
Inositol 1,4,5-triphosphate receptor associated 2
SynonymsLRMP
JAW1
DescriptionFUNCTION: Plays a role in the delivery of peptides to major histocompatibility complex (MHC) class I molecules; this occurs in a transporter associated with antigen processing (TAP)-independent manner. May play a role in taste signal transduction via ITPR3. May play a role during fertilization in pronucleus congression and fusion. Plays a role in maintaining nuclear shape, maybe as a component of the LINC complex and through interaction with microtubules. .

AccessionsENST00000555885.1
ENST00000554942.5
ENST00000550945.5
ENST00000536173.5
ENST00000557489
ENST00000556887
ENST00000361433.6
G3V3C2
A0A1B0GU45
ENST00000557489.6 [Q12912-2]
ENST00000555877.5
F5H006
F8VRE4
ENST00000354454.7 [Q12912-2]
G3V513
ENST00000554272.5
H0YJ39
ENST00000547044.5 [Q12912-2]
H0YJC6
ENST00000556887.6 [Q12912-2]
G3V2F6
Q12912
ENST00000636465.1
ENST00000548766.5 [Q12912-2]
A0A0G2JL87
F8W9L6