Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 15 studies | 27% ± 13% | |
| fibroblast | 10 studies | 24% ± 8% | |
| macrophage | 9 studies | 30% ± 10% | |
| adipocyte | 9 studies | 31% ± 11% | |
| astrocyte | 9 studies | 30% ± 13% | |
| epithelial cell | 8 studies | 38% ± 22% | |
| oligodendrocyte | 8 studies | 38% ± 11% | |
| glutamatergic neuron | 7 studies | 43% ± 23% | |
| GABAergic neuron | 6 studies | 40% ± 22% | |
| microglial cell | 6 studies | 31% ± 9% | |
| oligodendrocyte precursor cell | 6 studies | 31% ± 15% | |
| type I pneumocyte | 6 studies | 22% ± 7% | |
| type II pneumocyte | 6 studies | 23% ± 5% | |
| neuron | 5 studies | 30% ± 15% | |
| interneuron | 5 studies | 48% ± 26% | |
| retina horizontal cell | 5 studies | 24% ± 5% | |
| cardiac muscle cell | 5 studies | 31% ± 7% | |
| dendritic cell | 5 studies | 23% ± 8% | |
| ciliated cell | 5 studies | 26% ± 8% | |
| goblet cell | 5 studies | 34% ± 27% | |
| smooth muscle cell | 5 studies | 19% ± 2% | |
| plasma cell | 4 studies | 29% ± 10% | |
| respiratory goblet cell | 4 studies | 22% ± 3% | |
| granule cell | 4 studies | 20% ± 5% | |
| retinal ganglion cell | 4 studies | 30% ± 10% | |
| myeloid cell | 4 studies | 26% ± 5% | |
| amacrine cell | 4 studies | 22% ± 5% | |
| retinal rod cell | 4 studies | 18% ± 1% | |
| hepatocyte | 4 studies | 52% ± 20% | |
| connective tissue cell | 4 studies | 18% ± 4% | |
| endothelial cell of lymphatic vessel | 4 studies | 24% ± 4% | |
| pericyte | 4 studies | 22% ± 5% | |
| type B pancreatic cell | 3 studies | 36% ± 17% | |
| plasmablast | 3 studies | 34% ± 14% | |
| retinal bipolar neuron | 3 studies | 20% ± 3% | |
| retinal cone cell | 3 studies | 22% ± 3% | |
| retinal pigment epithelial cell | 3 studies | 36% ± 25% | |
| mesothelial cell | 3 studies | 23% ± 5% | |
| lymphocyte | 3 studies | 21% ± 6% | |
| Mueller cell | 3 studies | 22% ± 4% | |
| glycinergic amacrine cell | 3 studies | 21% ± 4% | |
| rod bipolar cell | 3 studies | 22% ± 5% | |
| alveolar macrophage | 3 studies | 30% ± 9% | |
| club cell | 3 studies | 25% ± 9% | |
| monocyte | 3 studies | 25% ± 5% | |
| basal cell | 3 studies | 42% ± 28% | |
| plasmacytoid dendritic cell | 3 studies | 20% ± 2% | |
| regulatory T cell | 3 studies | 16% ± 0% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 3274.01 | 1445 / 1445 | 100% | 34.59 | 183 / 183 |
| lung | 100% | 3004.38 | 578 / 578 | 100% | 24.37 | 1154 / 1155 |
| breast | 100% | 3096.59 | 459 / 459 | 100% | 34.03 | 1116 / 1118 |
| prostate | 100% | 2896.34 | 245 / 245 | 100% | 27.61 | 500 / 502 |
| brain | 100% | 2562.76 | 2633 / 2642 | 100% | 20.44 | 704 / 705 |
| pancreas | 100% | 3139.94 | 328 / 328 | 99% | 22.56 | 177 / 178 |
| liver | 100% | 4622.61 | 226 / 226 | 99% | 23.23 | 403 / 406 |
| adrenal gland | 100% | 6180.18 | 258 / 258 | 99% | 21.46 | 228 / 230 |
| uterus | 100% | 3177.60 | 170 / 170 | 99% | 18.25 | 455 / 459 |
| thymus | 100% | 2791.45 | 653 / 653 | 99% | 23.18 | 599 / 605 |
| bladder | 100% | 3203.57 | 21 / 21 | 98% | 19.70 | 496 / 504 |
| kidney | 100% | 2595.27 | 89 / 89 | 98% | 24.26 | 884 / 901 |
| intestine | 100% | 2915.63 | 966 / 966 | 98% | 26.66 | 517 / 527 |
| stomach | 100% | 3001.82 | 359 / 359 | 98% | 27.73 | 280 / 286 |
| ovary | 100% | 3409.91 | 180 / 180 | 93% | 12.14 | 400 / 430 |
| skin | 100% | 3222.93 | 1805 / 1809 | 89% | 19.03 | 422 / 472 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 14.73 | 29 / 29 |
| muscle | 100% | 4010.43 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 2598.96 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 26.99 | 1 / 1 |
| blood vessel | 100% | 2951.72 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 100% | 3149.86 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| heart | 98% | 2622.27 | 845 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 15.44 | 43 / 45 |
| eye | 0% | 0 | 0 / 0 | 57% | 7.66 | 46 / 80 |
| peripheral blood | 43% | 1583.94 | 403 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0001933 | Biological process | negative regulation of protein phosphorylation |
| GO_0051209 | Biological process | release of sequestered calcium ion into cytosol |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0016020 | Cellular component | membrane |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0019901 | Molecular function | protein kinase binding |
| GO_0030292 | Molecular function | protein tyrosine kinase inhibitor activity |
| Gene name | IBTK |
| Protein name | Inhibitor of Bruton tyrosine kinase IBTK protein Inhibitor of Bruton tyrosine kinase (IBtk) |
| Synonyms | BTKI KIAA1417 |
| Description | FUNCTION: Acts as an inhibitor of BTK tyrosine kinase activity, thereby playing a role in B-cell development. Down-regulates BTK kinase activity, leading to interference with BTK-mediated calcium mobilization and NF-kappa-B-driven transcription. . |
| Accessions | ENST00000634585 ENST00000635384 ENST00000503631.5 B7ZLD4 Q9P2D0 ENST00000634695 D6R9F4 ENST00000306270.12 [Q9P2D0-1] H0Y9N7 B7ZLE0 ENST00000635454.2 [Q9P2D0-1] ENST00000471036.1 E9PDR5 ENST00000503400.5 ENST00000635314 ENST00000634571 ENST00000610980.4 ENST00000510291.5 E7EPI0 |