IBTK report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0001933Biological processnegative regulation of protein phosphorylation
GO_0051209Biological processrelease of sequestered calcium ion into cytosol
GO_0005654Cellular componentnucleoplasm
GO_0016020Cellular componentmembrane
GO_0005737Cellular componentcytoplasm
GO_0019901Molecular functionprotein kinase binding
GO_0030292Molecular functionprotein tyrosine kinase inhibitor activity

IV. Literature review

[source]
Gene nameIBTK
Protein nameInhibitor of Bruton tyrosine kinase
IBTK protein
Inhibitor of Bruton tyrosine kinase (IBtk)
SynonymsBTKI
KIAA1417
DescriptionFUNCTION: Acts as an inhibitor of BTK tyrosine kinase activity, thereby playing a role in B-cell development. Down-regulates BTK kinase activity, leading to interference with BTK-mediated calcium mobilization and NF-kappa-B-driven transcription. .

AccessionsENST00000634585
ENST00000635384
ENST00000503631.5
B7ZLD4
Q9P2D0
ENST00000634695
D6R9F4
ENST00000306270.12 [Q9P2D0-1]
H0Y9N7
B7ZLE0
ENST00000635454.2 [Q9P2D0-1]
ENST00000471036.1
E9PDR5
ENST00000503400.5
ENST00000635314
ENST00000634571
ENST00000610980.4
ENST00000510291.5
E7EPI0