HES7 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of HES7 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of HES7 at tissue level.

III. Associated gene sets

GO_0001501Biological processskeletal system development
GO_0007498Biological processmesoderm development
GO_0050767Biological processregulation of neurogenesis
GO_0036342Biological processpost-anal tail morphogenesis
GO_0009952Biological processanterior/posterior pattern specification
GO_0007219Biological processNotch signaling pathway
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0048511Biological processrhythmic process
GO_0001756Biological processsomitogenesis
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0046983Molecular functionprotein dimerization activity
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene nameHES7
Protein nameHes family bHLH transcription factor 7
Transcription factor HES-7 (hHes7) (Class B basic helix-loop-helix protein 37) (bHLHb37) (Hairy and enhancer of split 7) (bHLH factor Hes7)
SynonymsBHLHB37
DescriptionFUNCTION: Transcriptional repressor. Represses transcription from both N box- and E box-containing promoters. May with HES1, cooperatively regulate somite formation in the presomitic mesoderm (PSM). May function as a segmentation clock, which is essential for coordinated somite segmentation (By similarity). .

AccessionsJ3KSH6
Q9BYE0
ENST00000317814.8 [Q9BYE0-1]
ENST00000577735.1
ENST00000541682.7 [Q9BYE0-2]