Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 17 studies | 35% ± 15% | |
| astrocyte | 16 studies | 37% ± 16% | |
| oligodendrocyte precursor cell | 14 studies | 39% ± 16% | |
| glutamatergic neuron | 13 studies | 60% ± 23% | |
| oligodendrocyte | 13 studies | 36% ± 13% | |
| GABAergic neuron | 11 studies | 56% ± 25% | |
| macrophage | 10 studies | 31% ± 14% | |
| microglial cell | 10 studies | 28% ± 12% | |
| fibroblast | 10 studies | 29% ± 11% | |
| epithelial cell | 9 studies | 35% ± 19% | |
| pericyte | 9 studies | 32% ± 16% | |
| adipocyte | 9 studies | 33% ± 9% | |
| ciliated cell | 7 studies | 28% ± 10% | |
| neuron | 7 studies | 49% ± 19% | |
| retinal ganglion cell | 7 studies | 45% ± 18% | |
| interneuron | 6 studies | 67% ± 18% | |
| amacrine cell | 6 studies | 35% ± 13% | |
| retina horizontal cell | 6 studies | 38% ± 17% | |
| endothelial cell of lymphatic vessel | 6 studies | 29% ± 9% | |
| smooth muscle cell | 6 studies | 30% ± 7% | |
| dendritic cell | 5 studies | 19% ± 3% | |
| club cell | 5 studies | 28% ± 10% | |
| type I pneumocyte | 5 studies | 34% ± 8% | |
| type II pneumocyte | 5 studies | 28% ± 7% | |
| granule cell | 4 studies | 58% ± 10% | |
| cardiac muscle cell | 4 studies | 32% ± 4% | |
| ON-bipolar cell | 4 studies | 36% ± 12% | |
| retinal cone cell | 4 studies | 49% ± 9% | |
| retinal rod cell | 4 studies | 35% ± 5% | |
| basal cell | 4 studies | 34% ± 21% | |
| respiratory goblet cell | 4 studies | 30% ± 13% | |
| myeloid cell | 4 studies | 29% ± 3% | |
| monocyte | 4 studies | 27% ± 3% | |
| B cell | 4 studies | 27% ± 7% | |
| T cell | 4 studies | 20% ± 3% | |
| erythrocyte | 4 studies | 48% ± 29% | |
| GABAergic interneuron | 3 studies | 64% ± 4% | |
| progenitor cell | 3 studies | 42% ± 8% | |
| plasma cell | 3 studies | 25% ± 5% | |
| GABAergic amacrine cell | 3 studies | 48% ± 8% | |
| Mueller cell | 3 studies | 32% ± 6% | |
| OFF-bipolar cell | 3 studies | 40% ± 3% | |
| glycinergic amacrine cell | 3 studies | 40% ± 3% | |
| rod bipolar cell | 3 studies | 27% ± 11% | |
| hepatocyte | 3 studies | 44% ± 15% | |
| retinal pigment epithelial cell | 3 studies | 33% ± 21% | |
| abnormal cell | 3 studies | 32% ± 17% | |
| ependymal cell | 3 studies | 38% ± 15% | |
| alveolar macrophage | 3 studies | 28% ± 6% | |
| lymphocyte | 3 studies | 30% ± 6% | |
| goblet cell | 3 studies | 44% ± 28% | |
| mucus secreting cell | 3 studies | 30% ± 8% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 7132.79 | 1445 / 1445 | 100% | 15.09 | 183 / 183 |
| prostate | 100% | 8464.69 | 245 / 245 | 100% | 23.19 | 501 / 502 |
| brain | 99% | 11044.16 | 2623 / 2642 | 98% | 18.51 | 693 / 705 |
| stomach | 100% | 6100.22 | 359 / 359 | 98% | 10.52 | 279 / 286 |
| breast | 100% | 5556.78 | 459 / 459 | 97% | 13.60 | 1085 / 1118 |
| thymus | 100% | 11424.76 | 653 / 653 | 97% | 10.63 | 586 / 605 |
| intestine | 100% | 7351.77 | 966 / 966 | 96% | 8.93 | 504 / 527 |
| pancreas | 100% | 3744.14 | 327 / 328 | 96% | 8.67 | 170 / 178 |
| skin | 100% | 6404.57 | 1809 / 1809 | 94% | 7.52 | 443 / 472 |
| lung | 100% | 5537.93 | 578 / 578 | 94% | 9.33 | 1082 / 1155 |
| bladder | 100% | 6705.10 | 21 / 21 | 93% | 7.51 | 467 / 504 |
| kidney | 100% | 5020.57 | 89 / 89 | 93% | 8.46 | 834 / 901 |
| adrenal gland | 100% | 4650.97 | 258 / 258 | 91% | 10.16 | 210 / 230 |
| uterus | 100% | 7944.84 | 170 / 170 | 90% | 7.51 | 414 / 459 |
| ovary | 100% | 6252.72 | 180 / 180 | 90% | 8.98 | 386 / 430 |
| liver | 100% | 2821.78 | 226 / 226 | 57% | 3.29 | 233 / 406 |
| adipose | 100% | 4802.40 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 100% | 5589.63 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 3.99 | 1 / 1 |
| blood vessel | 100% | 5932.12 | 1332 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 99% | 3579.48 | 797 / 803 | 0% | 0 | 0 / 0 |
| heart | 95% | 3330.43 | 822 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 87% | 7.81 | 39 / 45 |
| eye | 0% | 0 | 0 / 0 | 83% | 5.61 | 66 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 79% | 7.08 | 23 / 29 |
| peripheral blood | 69% | 2471.45 | 639 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0016567 | Biological process | protein ubiquitination |
| GO_0006006 | Biological process | glucose metabolic process |
| GO_0042593 | Biological process | glucose homeostasis |
| GO_0016020 | Cellular component | membrane |
| GO_0004842 | Molecular function | ubiquitin-protein transferase activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | HECTD4 |
| Protein name | HEEL protein ( C12orf51protein, HECTD4 protein ) HEEL protein ( C12ord51protein, HECTD4 protein ) Probable E3 ubiquitin-protein ligase HECTD4 (EC 2.3.2.26) (HECT domain-containing protein 4) (HECT-type E3 ubiquitin transferase HECTD4) HECT domain E3 ubiquitin protein ligase 4 |
| Synonyms | HEEL C12ord51 C12orf51 KIAA0614 |
| Description | FUNCTION: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. . |
| Accessions | A0A494C150 ENST00000682272.1 ENST00000550724.2 ENST00000550722.5 A0A286P060 V9GYT9 A0A286P059 F8VWT9 ENST00000377560.9 Q9Y4D8 F8VU57 J3KPF0 A0A804HJX8 ENST00000651701.1 ENST00000548588.2 |