Name | Number of supported studies | Average coverage | |
---|---|---|---|
plasmablast | 5 studies | 36% ± 15% | |
effector CD8-positive, alpha-beta T cell | 4 studies | 26% ± 10% | |
CD4-positive, alpha-beta T cell | 4 studies | 29% ± 2% | |
hematopoietic precursor cell | 3 studies | 21% ± 3% | |
plasma cell | 3 studies | 25% ± 3% | |
erythrocyte | 3 studies | 34% ± 11% | |
natural killer cell | 3 studies | 25% ± 11% | |
CD8-positive, alpha-beta T cell | 3 studies | 26% ± 2% |
Insufficient scRNA-seq data for expression of H1-5 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
intestine | 53% | 9.51 | 511 / 966 | 41% | 11.45 | 218 / 527 |
stomach | 42% | 3.52 | 150 / 359 | 50% | 9.81 | 144 / 286 |
esophagus | 33% | 1.61 | 484 / 1445 | 57% | 1.67 | 105 / 183 |
ovary | 16% | 0.51 | 28 / 180 | 73% | 4.92 | 314 / 430 |
lung | 55% | 4.35 | 320 / 578 | 31% | 5.86 | 359 / 1155 |
peripheral blood | 77% | 18.10 | 716 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 72% | 4.79 | 21 / 29 |
spleen | 72% | 11.98 | 174 / 241 | 0% | 0 | 0 / 0 |
breast | 51% | 3.22 | 234 / 459 | 19% | 4.64 | 217 / 1118 |
uterus | 17% | 0.40 | 29 / 170 | 49% | 2.42 | 224 / 459 |
skin | 54% | 4.03 | 971 / 1809 | 12% | 0.21 | 57 / 472 |
bladder | 19% | 0.90 | 4 / 21 | 34% | 30.33 | 171 / 504 |
adipose | 46% | 2.75 | 551 / 1204 | 0% | 0 | 0 / 0 |
thymus | 34% | 1.67 | 222 / 653 | 11% | 0.84 | 67 / 605 |
tonsil | 0% | 0 | 0 / 0 | 44% | 1.14 | 20 / 45 |
brain | 21% | 0.84 | 548 / 2642 | 10% | 0.92 | 69 / 705 |
blood vessel | 28% | 1.13 | 368 / 1335 | 0% | 0 | 0 / 0 |
liver | 21% | 0.69 | 47 / 226 | 5% | 0.13 | 22 / 406 |
adrenal gland | 22% | 0.81 | 58 / 258 | 3% | 0.08 | 8 / 230 |
pancreas | 13% | 0.38 | 43 / 328 | 12% | 1.42 | 22 / 178 |
prostate | 18% | 0.56 | 43 / 245 | 5% | 0.13 | 26 / 502 |
heart | 23% | 0.72 | 195 / 861 | 0% | 0 | 0 / 0 |
muscle | 16% | 0.44 | 128 / 803 | 0% | 0 | 0 / 0 |
kidney | 12% | 0.47 | 11 / 89 | 1% | 0.47 | 12 / 901 |
eye | 0% | 0 | 0 / 0 | 1% | 0.01 | 1 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006325 | Biological process | chromatin organization |
GO_0071169 | Biological process | establishment of protein localization to chromatin |
GO_0030261 | Biological process | chromosome condensation |
GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
GO_0006334 | Biological process | nucleosome assembly |
GO_0050821 | Biological process | protein stabilization |
GO_0007517 | Biological process | muscle organ development |
GO_0045910 | Biological process | negative regulation of DNA recombination |
GO_0005730 | Cellular component | nucleolus |
GO_0000786 | Cellular component | nucleosome |
GO_0000792 | Cellular component | heterochromatin |
GO_0000791 | Cellular component | euchromatin |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005694 | Cellular component | chromosome |
GO_0000785 | Cellular component | chromatin |
GO_0005634 | Cellular component | nucleus |
GO_0003690 | Molecular function | double-stranded DNA binding |
GO_0031492 | Molecular function | nucleosomal DNA binding |
GO_0030527 | Molecular function | structural constituent of chromatin |
GO_0042826 | Molecular function | histone deacetylase binding |
GO_0003723 | Molecular function | RNA binding |
GO_0031490 | Molecular function | chromatin DNA binding |
GO_0005515 | Molecular function | protein binding |
Gene name | H1-5 |
Protein name | Histone H1.5 (Histone H1a) (Histone H1b) (Histone H1s-3) |
Synonyms | HIST1H1B H1F5 |
Description | FUNCTION: Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity). . |
Accessions | ENST00000331442.5 P16401 |