H1-5 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of H1-5 at tissue level.

III. Associated gene sets

GO_0006325Biological processchromatin organization
GO_0071169Biological processestablishment of protein localization to chromatin
GO_0030261Biological processchromosome condensation
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0006334Biological processnucleosome assembly
GO_0050821Biological processprotein stabilization
GO_0007517Biological processmuscle organ development
GO_0045910Biological processnegative regulation of DNA recombination
GO_0005730Cellular componentnucleolus
GO_0000786Cellular componentnucleosome
GO_0000792Cellular componentheterochromatin
GO_0000791Cellular componenteuchromatin
GO_0005654Cellular componentnucleoplasm
GO_0005694Cellular componentchromosome
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0003690Molecular functiondouble-stranded DNA binding
GO_0031492Molecular functionnucleosomal DNA binding
GO_0030527Molecular functionstructural constituent of chromatin
GO_0042826Molecular functionhistone deacetylase binding
GO_0003723Molecular functionRNA binding
GO_0031490Molecular functionchromatin DNA binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameH1-5
Protein nameHistone H1.5 (Histone H1a) (Histone H1b) (Histone H1s-3)
SynonymsHIST1H1B
H1F5
DescriptionFUNCTION: Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity). .

AccessionsENST00000331442.5
P16401