GTF2IRD1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0014886Biological processtransition between slow and fast fiber
GO_0006366Biological processtranscription by RNA polymerase II
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0006355Biological processregulation of DNA-templated transcription
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005634Cellular componentnucleus
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0001227Molecular functionDNA-binding transcription repressor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene nameGTF2IRD1
Protein nameUncharacterized protein GTF2IRD1
General transcription factor II-I repeat domain-containing protein 1 (GTF2I repeat domain-containing protein 1) (General transcription factor III) (MusTRD1/BEN) (Muscle TFII-I repeat domain-containing protein 1) (Slow-muscle-fiber enhancer-binding protein) (USE B1-binding protein) (Williams-Beuren syndrome chromosomal region 11 protein) (Williams-Beuren syndrome chromosomal region 12 protein)
GTF2I repeat domain containing 1
SynonymsWBSCR12
WBSCR11
RBAP2
CREAM1
MUSTRD1
GTF3
DescriptionFUNCTION: May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer (USE B1). Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8 (By similarity). .

AccessionsENST00000470715.1
ENST00000476977.5
H7C4Q8
Q75MX6
ENST00000455841.6 [Q9UHL9-3]
ENST00000424337.7 [Q9UHL9-2]
ENST00000265755.7 [Q9UHL9-1]
Q9UHL9
E9PFE2