Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| astrocyte | 10 studies | 28% ± 11% | |
| oligodendrocyte precursor cell | 7 studies | 25% ± 9% | |
| interneuron | 6 studies | 38% ± 21% | |
| GABAergic neuron | 6 studies | 37% ± 14% | |
| epithelial cell | 5 studies | 35% ± 13% | |
| adipocyte | 5 studies | 20% ± 2% | |
| cardiac muscle cell | 5 studies | 36% ± 10% | |
| type I pneumocyte | 5 studies | 32% ± 8% | |
| endothelial cell | 4 studies | 42% ± 21% | |
| glutamatergic neuron | 4 studies | 37% ± 12% | |
| neuron | 4 studies | 38% ± 18% | |
| retina horizontal cell | 4 studies | 23% ± 4% | |
| retinal cone cell | 4 studies | 26% ± 7% | |
| retinal rod cell | 4 studies | 42% ± 8% | |
| type II pneumocyte | 4 studies | 18% ± 3% | |
| basal cell | 4 studies | 24% ± 8% | |
| oligodendrocyte | 4 studies | 21% ± 5% | |
| GABAergic interneuron | 3 studies | 29% ± 12% | |
| granule cell | 3 studies | 20% ± 4% | |
| amacrine cell | 3 studies | 27% ± 7% | |
| glycinergic amacrine cell | 3 studies | 21% ± 5% | |
| retinal pigment epithelial cell | 3 studies | 49% ± 20% | |
| ciliated cell | 3 studies | 27% ± 6% | |
| club cell | 3 studies | 18% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| ovary | 100% | 1798.61 | 180 / 180 | 100% | 27.54 | 429 / 430 |
| uterus | 100% | 2124.88 | 170 / 170 | 100% | 30.89 | 457 / 459 |
| esophagus | 100% | 3013.42 | 1445 / 1445 | 99% | 34.22 | 182 / 183 |
| prostate | 100% | 2640.12 | 245 / 245 | 99% | 16.12 | 497 / 502 |
| bladder | 100% | 2519.81 | 21 / 21 | 99% | 28.99 | 497 / 504 |
| stomach | 100% | 1859.37 | 359 / 359 | 99% | 32.37 | 282 / 286 |
| lung | 99% | 2096.30 | 575 / 578 | 99% | 21.36 | 1138 / 1155 |
| thymus | 100% | 3317.69 | 653 / 653 | 98% | 34.03 | 592 / 605 |
| breast | 99% | 1238.95 | 454 / 459 | 99% | 22.64 | 1106 / 1118 |
| intestine | 99% | 1858.14 | 955 / 966 | 99% | 35.41 | 521 / 527 |
| adrenal gland | 100% | 2057.79 | 258 / 258 | 97% | 16.82 | 224 / 230 |
| skin | 100% | 2753.80 | 1809 / 1809 | 96% | 16.90 | 451 / 472 |
| kidney | 100% | 2478.30 | 89 / 89 | 95% | 14.89 | 858 / 901 |
| brain | 95% | 985.25 | 2500 / 2642 | 100% | 18.63 | 702 / 705 |
| pancreas | 91% | 829.40 | 297 / 328 | 98% | 21.53 | 174 / 178 |
| liver | 45% | 302.04 | 102 / 226 | 57% | 6.06 | 231 / 406 |
| eye | 0% | 0 | 0 / 0 | 100% | 18.39 | 80 / 80 |
| muscle | 100% | 6394.05 | 803 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 26.05 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 30.11 | 1 / 1 |
| blood vessel | 98% | 1116.30 | 1311 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 98% | 973.59 | 1182 / 1204 | 0% | 0 | 0 / 0 |
| heart | 92% | 1232.91 | 790 / 861 | 0% | 0 | 0 / 0 |
| spleen | 30% | 167.53 | 73 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 13% | 125.10 | 120 / 929 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 0.19 | 1 / 29 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0014886 | Biological process | transition between slow and fast fiber |
| GO_0006366 | Biological process | transcription by RNA polymerase II |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0006355 | Biological process | regulation of DNA-templated transcription |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0005634 | Cellular component | nucleus |
| GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO_0003700 | Molecular function | DNA-binding transcription factor activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO_0001227 | Molecular function | DNA-binding transcription repressor activity, RNA polymerase II-specific |
| Gene name | GTF2IRD1 |
| Protein name | Uncharacterized protein GTF2IRD1 General transcription factor II-I repeat domain-containing protein 1 (GTF2I repeat domain-containing protein 1) (General transcription factor III) (MusTRD1/BEN) (Muscle TFII-I repeat domain-containing protein 1) (Slow-muscle-fiber enhancer-binding protein) (USE B1-binding protein) (Williams-Beuren syndrome chromosomal region 11 protein) (Williams-Beuren syndrome chromosomal region 12 protein) GTF2I repeat domain containing 1 |
| Synonyms | WBSCR12 WBSCR11 RBAP2 CREAM1 MUSTRD1 GTF3 |
| Description | FUNCTION: May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer (USE B1). Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8 (By similarity). . |
| Accessions | ENST00000470715.1 ENST00000476977.5 H7C4Q8 Q75MX6 ENST00000455841.6 [Q9UHL9-3] ENST00000424337.7 [Q9UHL9-2] ENST00000265755.7 [Q9UHL9-1] Q9UHL9 E9PFE2 |