Name | Number of supported studies | Average coverage | |
---|---|---|---|
macrophage | 13 studies | 44% ± 21% | |
non-classical monocyte | 12 studies | 28% ± 13% | |
glutamatergic neuron | 12 studies | 46% ± 25% | |
B cell | 10 studies | 31% ± 12% | |
GABAergic neuron | 10 studies | 57% ± 28% | |
adipocyte | 10 studies | 53% ± 12% | |
dendritic cell | 10 studies | 41% ± 18% | |
astrocyte | 10 studies | 38% ± 15% | |
classical monocyte | 9 studies | 21% ± 9% | |
myeloid cell | 9 studies | 38% ± 15% | |
microglial cell | 9 studies | 47% ± 14% | |
monocyte | 8 studies | 43% ± 19% | |
neuron | 6 studies | 33% ± 11% | |
retina horizontal cell | 6 studies | 34% ± 16% | |
endothelial cell | 5 studies | 26% ± 7% | |
ciliated cell | 5 studies | 26% ± 11% | |
oligodendrocyte precursor cell | 5 studies | 28% ± 6% | |
pericyte | 5 studies | 32% ± 12% | |
interneuron | 5 studies | 64% ± 22% | |
conventional dendritic cell | 4 studies | 23% ± 13% | |
mononuclear phagocyte | 4 studies | 28% ± 9% | |
oligodendrocyte | 4 studies | 24% ± 12% | |
mast cell | 4 studies | 23% ± 8% | |
hematopoietic precursor cell | 3 studies | 23% ± 10% | |
retinal ganglion cell | 3 studies | 20% ± 1% | |
GABAergic amacrine cell | 3 studies | 25% ± 9% | |
smooth muscle cell | 3 studies | 25% ± 10% | |
alveolar macrophage | 3 studies | 63% ± 11% | |
club cell | 3 studies | 22% ± 2% | |
type II pneumocyte | 3 studies | 26% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 3889.07 | 459 / 459 | 99% | 12.45 | 1109 / 1118 |
thymus | 100% | 1478.46 | 651 / 653 | 99% | 8.49 | 597 / 605 |
brain | 99% | 2572.04 | 2604 / 2642 | 99% | 12.83 | 698 / 705 |
prostate | 98% | 2007.38 | 239 / 245 | 100% | 17.52 | 502 / 502 |
pancreas | 98% | 1270.37 | 323 / 328 | 98% | 9.19 | 175 / 178 |
lung | 100% | 2633.87 | 577 / 578 | 97% | 11.77 | 1116 / 1155 |
ovary | 100% | 1160.57 | 180 / 180 | 95% | 6.93 | 407 / 430 |
bladder | 95% | 898.76 | 20 / 21 | 91% | 7.60 | 460 / 504 |
intestine | 96% | 1433.45 | 925 / 966 | 86% | 5.83 | 454 / 527 |
uterus | 98% | 1437.75 | 166 / 170 | 84% | 5.93 | 386 / 459 |
kidney | 91% | 731.60 | 81 / 89 | 89% | 5.57 | 801 / 901 |
adrenal gland | 98% | 1266.50 | 253 / 258 | 80% | 10.70 | 183 / 230 |
esophagus | 84% | 629.50 | 1209 / 1445 | 91% | 7.39 | 166 / 183 |
stomach | 84% | 697.02 | 303 / 359 | 89% | 6.26 | 255 / 286 |
skin | 82% | 942.69 | 1477 / 1809 | 91% | 14.49 | 430 / 472 |
adipose | 100% | 4573.21 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 20.59 | 29 / 29 |
spleen | 100% | 5457.66 | 241 / 241 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 96% | 18.77 | 77 / 80 |
tonsil | 0% | 0 | 0 / 0 | 96% | 8.33 | 43 / 45 |
peripheral blood | 91% | 2481.87 | 850 / 929 | 0% | 0 | 0 / 0 |
liver | 29% | 197.63 | 65 / 226 | 59% | 4.79 | 238 / 406 |
heart | 78% | 757.01 | 674 / 861 | 0% | 0 | 0 / 0 |
blood vessel | 78% | 655.20 | 1035 / 1335 | 0% | 0 | 0 / 0 |
muscle | 8% | 47.07 | 67 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007165 | Biological process | signal transduction |
GO_0031623 | Biological process | receptor internalization |
GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
GO_0006468 | Biological process | protein phosphorylation |
GO_0002029 | Biological process | desensitization of G protein-coupled receptor signaling pathway |
GO_0042995 | Cellular component | cell projection |
GO_0098793 | Cellular component | presynapse |
GO_0005829 | Cellular component | cytosol |
GO_0098794 | Cellular component | postsynapse |
GO_0005886 | Cellular component | plasma membrane |
GO_0004703 | Molecular function | G protein-coupled receptor kinase activity |
GO_0047696 | Molecular function | beta-adrenergic receptor kinase activity |
GO_0005515 | Molecular function | protein binding |
GO_0004672 | Molecular function | protein kinase activity |
GO_0005524 | Molecular function | ATP binding |
GO_0001664 | Molecular function | G protein-coupled receptor binding |
Gene name | GRK3 |
Protein name | Alternative protein ADRBK2 G protein-coupled receptor kinase 3 G protein-coupled receptor kinase 3 (EC 2.7.11.15) (Beta-adrenergic receptor kinase 2) (Beta-ARK-2) |
Synonyms | BARK2 ADRBK2 |
Description | FUNCTION: Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors. . |
Accessions | L0R4T6 ENST00000324198.11 H7C099 L8EAE0 P35626 ENST00000455558.2 |