Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| fibroblast | 12 studies | 20% ± 5% | |
| endothelial cell | 11 studies | 26% ± 9% | |
| oligodendrocyte precursor cell | 9 studies | 28% ± 13% | |
| oligodendrocyte | 8 studies | 25% ± 7% | |
| natural killer cell | 7 studies | 18% ± 3% | |
| epithelial cell | 7 studies | 31% ± 12% | |
| astrocyte | 7 studies | 29% ± 12% | |
| glutamatergic neuron | 7 studies | 39% ± 22% | |
| microglial cell | 6 studies | 21% ± 5% | |
| connective tissue cell | 6 studies | 24% ± 4% | |
| endothelial cell of lymphatic vessel | 6 studies | 20% ± 2% | |
| interneuron | 6 studies | 33% ± 19% | |
| CD16-negative, CD56-bright natural killer cell, human | 5 studies | 19% ± 3% | |
| pericyte | 5 studies | 20% ± 3% | |
| basal cell | 5 studies | 27% ± 7% | |
| smooth muscle cell | 5 studies | 18% ± 3% | |
| GABAergic neuron | 5 studies | 42% ± 12% | |
| ciliated cell | 4 studies | 26% ± 9% | |
| myofibroblast cell | 4 studies | 21% ± 4% | |
| goblet cell | 4 studies | 26% ± 5% | |
| macrophage | 4 studies | 22% ± 5% | |
| mature NK T cell | 3 studies | 16% ± 0% | |
| progenitor cell | 3 studies | 20% ± 3% | |
| amacrine cell | 3 studies | 25% ± 7% | |
| retina horizontal cell | 3 studies | 23% ± 3% | |
| lymphocyte | 3 studies | 21% ± 7% | |
| abnormal cell | 3 studies | 25% ± 5% | |
| regulatory T cell | 3 studies | 19% ± 2% | |
| intestinal crypt stem cell | 3 studies | 15% ± 0% | |
| neuron | 3 studies | 37% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 100% | 3127.02 | 459 / 459 | 100% | 35.98 | 1118 / 1118 |
| esophagus | 100% | 2724.85 | 1445 / 1445 | 100% | 33.72 | 183 / 183 |
| ovary | 100% | 3797.71 | 180 / 180 | 100% | 19.83 | 430 / 430 |
| brain | 100% | 2564.49 | 2636 / 2642 | 100% | 35.81 | 705 / 705 |
| thymus | 100% | 3381.30 | 653 / 653 | 100% | 35.70 | 603 / 605 |
| lung | 100% | 2379.70 | 576 / 578 | 100% | 27.13 | 1155 / 1155 |
| prostate | 100% | 2747.98 | 245 / 245 | 100% | 24.19 | 500 / 502 |
| uterus | 100% | 4149.11 | 170 / 170 | 99% | 30.98 | 456 / 459 |
| bladder | 100% | 3331.43 | 21 / 21 | 99% | 25.36 | 500 / 504 |
| pancreas | 99% | 1552.95 | 326 / 328 | 99% | 26.22 | 177 / 178 |
| stomach | 100% | 2135.49 | 359 / 359 | 99% | 25.77 | 282 / 286 |
| intestine | 100% | 3280.11 | 966 / 966 | 98% | 26.62 | 519 / 527 |
| adrenal gland | 100% | 2201.30 | 258 / 258 | 98% | 23.30 | 226 / 230 |
| kidney | 100% | 1746.28 | 89 / 89 | 98% | 22.21 | 883 / 901 |
| skin | 100% | 4334.12 | 1809 / 1809 | 93% | 22.73 | 440 / 472 |
| liver | 100% | 1424.45 | 226 / 226 | 91% | 12.18 | 370 / 406 |
| adipose | 100% | 3053.21 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 3305.28 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 21.25 | 29 / 29 |
| spleen | 100% | 2643.10 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 24.24 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 6.81 | 1 / 1 |
| muscle | 100% | 1762.87 | 801 / 803 | 0% | 0 | 0 / 0 |
| heart | 98% | 2170.58 | 847 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 79% | 13.24 | 63 / 80 |
| peripheral blood | 44% | 1093.75 | 410 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0045176 | Biological process | apical protein localization |
| GO_0006893 | Biological process | Golgi to plasma membrane transport |
| GO_2000009 | Biological process | negative regulation of protein localization to cell surface |
| GO_0015031 | Biological process | protein transport |
| GO_0006888 | Biological process | endoplasmic reticulum to Golgi vesicle-mediated transport |
| GO_0010360 | Biological process | negative regulation of anion channel activity |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0032991 | Cellular component | protein-containing complex |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0030425 | Cellular component | dendrite |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0014069 | Cellular component | postsynaptic density |
| GO_0030140 | Cellular component | trans-Golgi network transport vesicle |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0030660 | Cellular component | Golgi-associated vesicle membrane |
| GO_0005765 | Cellular component | lysosomal membrane |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0044325 | Molecular function | transmembrane transporter binding |
| GO_0140313 | Molecular function | molecular sequestering activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | GOPC |
| Protein name | Golgi-associated PDZ and coiled-coil motif-containing protein (CFTR-associated ligand) (Fused in glioblastoma) (PDZ protein interacting specifically with TC10) (PIST) Golgi-associated PDZ and coiled-coil motif containing protein transcript variant 4 Golgi associated PDZ and coiled-coil motif containing (Golgi-associated PDZ and coiled-coil motif containing protein transcript variant 3) |
| Synonyms | CAL FIG |
| Description | FUNCTION: Plays a role in intracellular protein trafficking and degradation . May regulate CFTR chloride currents and acid-induced ASIC3 currents by modulating cell surface expression of both channels (By similarity). May also regulate the intracellular trafficking of the ADR1B receptor . May play a role in autophagy (By similarity). Together with MARCHF2 mediates the ubiquitination and lysosomal degradation of CFTR . Overexpression results in CFTR intracellular retention and lysosomaldegradation in the lysosomes . . |
| Accessions | F5H1Y4 ENST00000368498.7 [Q9HD26-1] Q9HD26 ENST00000535237.2 T1WFC1 ENST00000052569.10 [Q9HD26-2] |