Name | Number of supported studies | Average coverage | |
---|---|---|---|
basal cell | 20 studies | 65% ± 20% | |
ciliated cell | 19 studies | 73% ± 17% | |
epithelial cell | 19 studies | 67% ± 20% | |
goblet cell | 12 studies | 66% ± 24% | |
type I pneumocyte | 10 studies | 64% ± 22% | |
secretory cell | 10 studies | 67% ± 24% | |
club cell | 9 studies | 61% ± 27% | |
type II pneumocyte | 8 studies | 49% ± 16% | |
enterocyte | 8 studies | 54% ± 25% | |
respiratory goblet cell | 6 studies | 65% ± 15% | |
enteroendocrine cell | 6 studies | 52% ± 27% | |
ionocyte | 5 studies | 35% ± 13% | |
progenitor cell | 5 studies | 53% ± 33% | |
transit amplifying cell | 5 studies | 56% ± 23% | |
mucus secreting cell | 5 studies | 63% ± 33% | |
keratinocyte | 5 studies | 62% ± 24% | |
deuterosomal cell | 4 studies | 47% ± 11% | |
duct epithelial cell | 4 studies | 85% ± 2% | |
squamous epithelial cell | 4 studies | 48% ± 25% | |
pancreatic A cell | 4 studies | 47% ± 9% | |
intestinal crypt stem cell | 4 studies | 48% ± 18% | |
brush cell | 4 studies | 39% ± 20% | |
neuroendocrine cell | 4 studies | 87% ± 5% | |
Mueller cell | 4 studies | 39% ± 18% | |
luminal hormone-sensing cell of mammary gland | 4 studies | 69% ± 12% | |
luminal cell of prostate epithelium | 4 studies | 78% ± 18% | |
hillock cell | 3 studies | 65% ± 32% | |
placental villous trophoblast | 3 studies | 81% ± 19% | |
serous secreting cell | 3 studies | 80% ± 7% | |
progenitor cell of mammary luminal epithelium | 3 studies | 53% ± 19% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 94% | 12725.20 | 231 / 245 | 90% | 3.31 | 450 / 502 |
stomach | 75% | 6125.78 | 271 / 359 | 84% | 4.75 | 241 / 286 |
lung | 87% | 3063.74 | 503 / 578 | 65% | 4.18 | 749 / 1155 |
intestine | 56% | 19106.50 | 542 / 966 | 90% | 6.22 | 474 / 527 |
skin | 72% | 9340.90 | 1305 / 1809 | 67% | 10.29 | 315 / 472 |
bladder | 52% | 5668.62 | 11 / 21 | 86% | 8.20 | 433 / 504 |
esophagus | 40% | 5473.56 | 574 / 1445 | 92% | 6.36 | 168 / 183 |
breast | 54% | 2239.15 | 248 / 459 | 72% | 2.07 | 801 / 1118 |
pancreas | 24% | 411.10 | 78 / 328 | 83% | 4.60 | 148 / 178 |
ureter | 0% | 0 | 0 / 0 | 100% | 5.50 | 1 / 1 |
tonsil | 0% | 0 | 0 / 0 | 93% | 5.59 | 42 / 45 |
uterus | 4% | 219.31 | 7 / 170 | 72% | 5.08 | 331 / 459 |
ovary | 0% | 0 | 0 / 180 | 27% | 0.56 | 115 / 430 |
kidney | 3% | 106.04 | 3 / 89 | 3% | 0.31 | 27 / 901 |
liver | 0% | 0 | 0 / 226 | 5% | 0.14 | 22 / 406 |
eye | 0% | 0 | 0 / 0 | 4% | 0.06 | 3 / 80 |
brain | 0% | 4.76 | 6 / 2642 | 2% | 0.02 | 11 / 705 |
adipose | 2% | 49.91 | 20 / 1204 | 0% | 0 | 0 / 0 |
thymus | 0% | 0 | 0 / 653 | 1% | 0.07 | 9 / 605 |
adrenal gland | 0% | 0 | 0 / 258 | 0% | 0.01 | 1 / 230 |
blood vessel | 0% | 8.14 | 4 / 1335 | 0% | 0 | 0 / 0 |
muscle | 0% | 3.51 | 2 / 803 | 0% | 0 | 0 / 0 |
heart | 0% | 1.67 | 1 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 8.93 | 1 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
GO_0043269 | Biological process | regulation of monoatomic ion transport |
GO_2000649 | Biological process | regulation of sodium ion transmembrane transporter activity |
GO_0006813 | Biological process | potassium ion transport |
GO_1902476 | Biological process | chloride transmembrane transport |
GO_0006814 | Biological process | sodium ion transport |
GO_0006821 | Biological process | chloride transport |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005886 | Cellular component | plasma membrane |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0051117 | Molecular function | ATPase binding |
GO_0017080 | Molecular function | sodium channel regulator activity |
GO_0005254 | Molecular function | chloride channel activity |
Gene name | FXYD3 |
Protein name | FXYD domain-containing ion transport regulator FXYD domain-containing ion transport regulator 3 (Chloride conductance inducer protein Mat-8) (Mammary tumor 8 kDa protein) (Phospholemman-like) (Sodium/potassium-transporting ATPase subunit FXYD3) |
Synonyms | MAT8 PLML |
Description | FUNCTION: Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell . Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1 . Induces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes . .; FUNCTION: [Isoform 1]: Decreases the apparent K+ and Na+ affinity of the sodium/potassium-transporting ATPase over a large range of membrane potentials. .; FUNCTION: [Isoform 2]: Decreases the apparent K+ affinity of the sodium/potassium-transporting ATPase only at slightly negative and positive membrane potentials and increases the apparent Na+ affinity over a large range of membrane potentials. . |
Accessions | ENST00000603181.5 [Q14802-1] S4R445 ENST00000605550.5 Q14802 ENST00000603449.5 [Q14802-5] ENST00000604404.6 [Q14802-1] ENST00000604621.5 [Q14802-1] A0A1S5UZ23 ENST00000603524.5 S4R3M2 ENST00000605677.1 [Q14802-4] ENST00000346446.9 [Q14802-2] ENST00000604804.5 ENST00000604255.5 [Q14802-3] ENST00000435734.6 [Q14802-2] ENST00000605552.5 [Q14802-5] ENST00000344013.10 [Q14802-2] |