FPR3 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of FPR3 at tissue level.

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0007204Biological processpositive regulation of cytosolic calcium ion concentration
GO_0006954Biological processinflammatory response
GO_0006935Biological processchemotaxis
GO_0007200Biological processphospholipase C-activating G protein-coupled receptor signaling pathway
GO_0002430Biological processcomplement receptor mediated signaling pathway
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0004982Molecular functionN-formyl peptide receptor activity
GO_0004875Molecular functioncomplement receptor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameFPR3
Protein nameN-formyl peptide receptor 3 (FMLP-related receptor II) (FMLP-R-II) (Formyl peptide receptor-like 2)
SynonymsFPRH1
FPRL2
DescriptionFUNCTION: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Acts as a receptor for humanin . .

AccessionsP25089
ENST00000595991.1
ENST00000339223.5