Name | Number of supported studies | Average coverage | |
---|---|---|---|
macrophage | 28 studies | 28% ± 10% | |
conventional dendritic cell | 9 studies | 24% ± 5% | |
monocyte | 7 studies | 27% ± 10% | |
myeloid cell | 6 studies | 30% ± 8% | |
dendritic cell | 5 studies | 28% ± 8% | |
mononuclear phagocyte | 4 studies | 30% ± 8% | |
tissue-resident macrophage | 3 studies | 28% ± 3% |
Insufficient scRNA-seq data for expression of FPR3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 98% | 1182.15 | 566 / 578 | 91% | 36.67 | 1051 / 1155 |
breast | 91% | 368.86 | 418 / 459 | 94% | 40.98 | 1053 / 1118 |
intestine | 96% | 396.43 | 926 / 966 | 73% | 18.90 | 387 / 527 |
esophagus | 80% | 207.09 | 1161 / 1445 | 74% | 16.06 | 136 / 183 |
bladder | 86% | 240.67 | 18 / 21 | 68% | 20.21 | 344 / 504 |
stomach | 69% | 146.57 | 247 / 359 | 79% | 24.63 | 226 / 286 |
adrenal gland | 97% | 688.97 | 251 / 258 | 39% | 5.12 | 90 / 230 |
pancreas | 51% | 110.85 | 168 / 328 | 83% | 24.47 | 148 / 178 |
thymus | 71% | 174.97 | 465 / 653 | 62% | 10.58 | 376 / 605 |
kidney | 54% | 167.00 | 48 / 89 | 77% | 32.61 | 692 / 901 |
uterus | 61% | 123.15 | 104 / 170 | 69% | 14.35 | 318 / 459 |
skin | 49% | 85.76 | 885 / 1809 | 77% | 23.06 | 365 / 472 |
ovary | 47% | 98.59 | 85 / 180 | 78% | 20.92 | 336 / 430 |
prostate | 75% | 142.75 | 183 / 245 | 47% | 5.83 | 237 / 502 |
adipose | 98% | 871.61 | 1179 / 1204 | 0% | 0 | 0 / 0 |
spleen | 98% | 716.67 | 235 / 241 | 0% | 0 | 0 / 0 |
liver | 51% | 111.85 | 115 / 226 | 46% | 7.39 | 188 / 406 |
lymph node | 0% | 0 | 0 / 0 | 93% | 29.25 | 27 / 29 |
tonsil | 0% | 0 | 0 / 0 | 91% | 27.73 | 41 / 45 |
blood vessel | 89% | 547.83 | 1193 / 1335 | 0% | 0 | 0 / 0 |
heart | 66% | 177.13 | 569 / 861 | 0% | 0 | 0 / 0 |
brain | 12% | 24.78 | 330 / 2642 | 45% | 9.05 | 316 / 705 |
peripheral blood | 45% | 114.73 | 414 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 25% | 3.42 | 20 / 80 |
muscle | 14% | 18.35 | 112 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007165 | Biological process | signal transduction |
GO_0007204 | Biological process | positive regulation of cytosolic calcium ion concentration |
GO_0006954 | Biological process | inflammatory response |
GO_0006935 | Biological process | chemotaxis |
GO_0007200 | Biological process | phospholipase C-activating G protein-coupled receptor signaling pathway |
GO_0002430 | Biological process | complement receptor mediated signaling pathway |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0004982 | Molecular function | N-formyl peptide receptor activity |
GO_0004875 | Molecular function | complement receptor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | FPR3 |
Protein name | N-formyl peptide receptor 3 (FMLP-related receptor II) (FMLP-R-II) (Formyl peptide receptor-like 2) |
Synonyms | FPRH1 FPRL2 |
Description | FUNCTION: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Acts as a receptor for humanin . . |
Accessions | P25089 ENST00000595991.1 ENST00000339223.5 |