FBXO32 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0014894Biological processresponse to denervation involved in regulation of muscle adaptation
GO_0016567Biological processprotein ubiquitination
GO_0071549Biological processcellular response to dexamethasone stimulus
GO_0019005Cellular componentSCF ubiquitin ligase complex
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0030018Cellular componentZ disc
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameFBXO32
Protein nameF-box only protein 32 (Atrogin-1) (Muscle atrophy F-box protein) (MAFbx)
F-box only protein 32
Synonyms
DescriptionFUNCTION: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1. .

FUNCTION: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1. .

FUNCTION: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1. .

FUNCTION: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1. .

AccessionsENST00000517956.5 [Q969P5-1]
ENST00000443022.2 [Q969P5-2]
I6L984
Q0VAQ6
Q498Y9
Q969P5