Name | Number of supported studies | Average coverage | |
---|---|---|---|
fibroblast | 6 studies | 23% ± 11% | |
connective tissue cell | 6 studies | 33% ± 9% | |
cardiac muscle cell | 5 studies | 35% ± 10% | |
smooth muscle cell | 4 studies | 23% ± 7% | |
interstitial cell of Cajal | 3 studies | 44% ± 5% | |
myofibroblast cell | 3 studies | 22% ± 3% | |
astrocyte | 3 studies | 37% ± 20% | |
oligodendrocyte precursor cell | 3 studies | 23% ± 8% | |
placental villous trophoblast | 3 studies | 48% ± 15% | |
Mueller cell | 3 studies | 22% ± 2% | |
GABAergic neuron | 3 studies | 33% ± 10% |
Insufficient scRNA-seq data for expression of FBN2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
uterus | 91% | 613.86 | 154 / 170 | 46% | 17.37 | 212 / 459 |
adrenal gland | 100% | 2269.02 | 258 / 258 | 25% | 3.99 | 57 / 230 |
thymus | 74% | 257.08 | 486 / 653 | 42% | 2.90 | 257 / 605 |
esophagus | 66% | 560.58 | 949 / 1445 | 45% | 7.53 | 82 / 183 |
prostate | 84% | 256.01 | 206 / 245 | 12% | 0.51 | 61 / 502 |
intestine | 70% | 204.21 | 675 / 966 | 24% | 0.97 | 126 / 527 |
ovary | 52% | 199.01 | 94 / 180 | 41% | 4.99 | 176 / 430 |
bladder | 52% | 134.00 | 11 / 21 | 39% | 6.77 | 199 / 504 |
stomach | 54% | 120.19 | 193 / 359 | 30% | 1.72 | 85 / 286 |
heart | 80% | 943.17 | 693 / 861 | 0% | 0 | 0 / 0 |
spleen | 67% | 175.22 | 162 / 241 | 0% | 0 | 0 / 0 |
peripheral blood | 64% | 201.27 | 598 / 929 | 0% | 0 | 0 / 0 |
brain | 12% | 20.64 | 308 / 2642 | 52% | 3.46 | 367 / 705 |
skin | 40% | 15162.56 | 721 / 1809 | 22% | 2.83 | 103 / 472 |
lung | 31% | 61.43 | 180 / 578 | 30% | 10.59 | 352 / 1155 |
breast | 13% | 25.26 | 58 / 459 | 41% | 3.54 | 461 / 1118 |
tonsil | 0% | 0 | 0 / 0 | 44% | 5.07 | 20 / 45 |
blood vessel | 24% | 72.29 | 314 / 1335 | 0% | 0 | 0 / 0 |
kidney | 12% | 24.63 | 11 / 89 | 7% | 0.76 | 66 / 901 |
pancreas | 2% | 5.13 | 7 / 328 | 15% | 0.78 | 26 / 178 |
adipose | 13% | 27.01 | 160 / 1204 | 0% | 0 | 0 / 0 |
liver | 2% | 2.65 | 4 / 226 | 1% | 0.04 | 4 / 406 |
muscle | 1% | 2.84 | 7 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007165 | Biological process | signal transduction |
GO_0060346 | Biological process | bone trabecula formation |
GO_0043010 | Biological process | camera-type eye development |
GO_0035583 | Biological process | sequestering of TGFbeta in extracellular matrix |
GO_0048048 | Biological process | embryonic eye morphogenesis |
GO_0030326 | Biological process | embryonic limb morphogenesis |
GO_0030501 | Biological process | positive regulation of bone mineralization |
GO_0045669 | Biological process | positive regulation of osteoblast differentiation |
GO_0009653 | Biological process | anatomical structure morphogenesis |
GO_0001527 | Cellular component | microfibril |
GO_0005576 | Cellular component | extracellular region |
GO_0062023 | Cellular component | collagen-containing extracellular matrix |
GO_0031012 | Cellular component | extracellular matrix |
GO_0005201 | Molecular function | extracellular matrix structural constituent |
GO_0030023 | Molecular function | extracellular matrix constituent conferring elasticity |
GO_0005509 | Molecular function | calcium ion binding |
GO_0005179 | Molecular function | hormone activity |
GO_0005515 | Molecular function | protein binding |
Gene name | FBN2 |
Protein name | Fibrillin 2 Alternative protein FBN2 Fibrillin-2 Fibrillin-2 [Cleaved into: Placensin] |
Synonyms | |
Description | FUNCTION: [Fibrillin-2]: Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-2-containing microfibrils regulate the early process of elastic fiber assembly. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively. .; FUNCTION: [Placensin]: Hormone secreted by trophoblasts that promotes trophoblast invasiveness . Has glucogenic activity: is able to increase plasma glucose levels (By similarity). . |
Accessions | L8E8V5 D6RJI3 A0A6B9XMH6 A0A6B9XP50 ENST00000262464.9 [P35556-1] ENST00000502468.5 E9PHW4 ENST00000508053.6 P35556 ENST00000508989.5 L8E7B8 A0A9H4AZX0 |