FANCC report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006289Biological processnucleotide-excision repair
GO_0048854Biological processbrain morphogenesis
GO_0002262Biological processmyeloid cell homeostasis
GO_0034599Biological processcellular response to oxidative stress
GO_0006281Biological processDNA repair
GO_0019430Biological processremoval of superoxide radicals
GO_0097150Biological processneuronal stem cell population maintenance
GO_0007281Biological processgerm cell development
GO_0036297Biological processinterstrand cross-link repair
GO_0065003Biological processprotein-containing complex assembly
GO_0043240Cellular componentFanconi anaemia nuclear complex
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0000785Cellular componentchromatin
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameFANCC
Protein nameFA complementation group C (Fanconi anemia complementation group C isoform 2)
Fanconi anemia group C protein (Protein FACC)
Fanconi anemia complementation group C isoform 1
FA complementation group C (cDNA FLJ61092, highly similar to Fanconi anemia group C protein)
FA complementation group C
SynonymsFAC
FACC
DescriptionFUNCTION: DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. .

FUNCTION: DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. .

AccessionsENST00000474949.1
Q00597
A0A024R9N2
ENST00000696262.1
ENST00000490972.7
B1ALR7
ENST00000433829.1
ENST00000649611.1
ENST00000649519.1
ENST00000375305.6
ENST00000647778.1
A0A8Q3WM43
A0A3B3ITN9
A0A3B3IU87
A0A3B3IS92
A0A087WW44
ENST00000647882.1
ENST00000649334.1
ENST00000289081.8
ENST00000649872.1
B4E3W2
A0A3B3IS26
A0A0S2Z3N5