Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| fibroblast | 34 studies | 39% ± 16% | |
| smooth muscle cell | 14 studies | 33% ± 14% | |
| myofibroblast cell | 12 studies | 38% ± 17% | |
| connective tissue cell | 11 studies | 44% ± 21% | |
| pericyte | 9 studies | 25% ± 8% | |
| adventitial cell | 4 studies | 24% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 99% | 12829.30 | 243 / 245 | 95% | 89.57 | 477 / 502 |
| lung | 100% | 15613.27 | 576 / 578 | 90% | 82.66 | 1044 / 1155 |
| breast | 99% | 6527.62 | 453 / 459 | 89% | 80.81 | 993 / 1118 |
| intestine | 96% | 20788.37 | 931 / 966 | 90% | 76.80 | 474 / 527 |
| stomach | 85% | 10950.93 | 304 / 359 | 90% | 99.54 | 256 / 286 |
| bladder | 100% | 20081.48 | 21 / 21 | 73% | 69.84 | 369 / 504 |
| ovary | 100% | 25270.59 | 180 / 180 | 73% | 54.18 | 314 / 430 |
| adrenal gland | 95% | 6630.48 | 246 / 258 | 71% | 76.50 | 164 / 230 |
| uterus | 99% | 28631.39 | 169 / 170 | 60% | 129.63 | 276 / 459 |
| esophagus | 82% | 11424.13 | 1178 / 1445 | 78% | 58.37 | 142 / 183 |
| skin | 56% | 6659.57 | 1014 / 1809 | 90% | 207.17 | 425 / 472 |
| thymus | 85% | 4531.39 | 558 / 653 | 39% | 17.67 | 238 / 605 |
| kidney | 79% | 6164.75 | 70 / 89 | 45% | 25.34 | 404 / 901 |
| pancreas | 19% | 690.16 | 63 / 328 | 93% | 160.53 | 165 / 178 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 98.35 | 29 / 29 |
| spleen | 100% | 15045.85 | 241 / 241 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 20681.15 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 97% | 7367.70 | 1171 / 1204 | 0% | 0 | 0 / 0 |
| liver | 53% | 2129.48 | 119 / 226 | 44% | 24.72 | 177 / 406 |
| heart | 80% | 5193.06 | 689 / 861 | 0% | 0 | 0 / 0 |
| brain | 2% | 55.75 | 45 / 2642 | 71% | 43.26 | 498 / 705 |
| eye | 0% | 0 | 0 / 0 | 70% | 55.10 | 56 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 58% | 32.06 | 26 / 45 |
| muscle | 4% | 137.79 | 33 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 2% | 68.65 | 15 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0033627 | Biological process | cell adhesion mediated by integrin |
| GO_1904027 | Biological process | negative regulation of collagen fibril organization |
| GO_0060392 | Biological process | negative regulation of SMAD protein signal transduction |
| GO_0010629 | Biological process | negative regulation of gene expression |
| GO_0045766 | Biological process | positive regulation of angiogenesis |
| GO_0007160 | Biological process | cell-matrix adhesion |
| GO_0010811 | Biological process | positive regulation of cell-substrate adhesion |
| GO_0008217 | Biological process | regulation of blood pressure |
| GO_0010628 | Biological process | positive regulation of gene expression |
| GO_0032966 | Biological process | negative regulation of collagen biosynthetic process |
| GO_0070373 | Biological process | negative regulation of ERK1 and ERK2 cascade |
| GO_0003180 | Biological process | aortic valve morphogenesis |
| GO_0030948 | Biological process | negative regulation of vascular endothelial growth factor receptor signaling pathway |
| GO_0007155 | Biological process | cell adhesion |
| GO_0016525 | Biological process | negative regulation of angiogenesis |
| GO_1901203 | Biological process | positive regulation of extracellular matrix assembly |
| GO_0050866 | Biological process | negative regulation of cell activation |
| GO_1905522 | Biological process | negative regulation of macrophage migration |
| GO_1901731 | Biological process | positive regulation of platelet aggregation |
| GO_0030194 | Biological process | positive regulation of blood coagulation |
| GO_1900747 | Biological process | negative regulation of vascular endothelial growth factor signaling pathway |
| GO_0030336 | Biological process | negative regulation of cell migration |
| GO_0048251 | Biological process | elastic fiber assembly |
| GO_0043065 | Biological process | positive regulation of apoptotic process |
| GO_0016477 | Biological process | cell migration |
| GO_0042127 | Biological process | regulation of cell population proliferation |
| GO_1900426 | Biological process | positive regulation of defense response to bacterium |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005576 | Cellular component | extracellular region |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005581 | Cellular component | collagen trimer |
| GO_0062023 | Cellular component | collagen-containing extracellular matrix |
| GO_1990971 | Cellular component | EMILIN complex |
| GO_0034668 | Cellular component | integrin alpha4-beta1 complex |
| GO_0030023 | Molecular function | extracellular matrix constituent conferring elasticity |
| GO_0060090 | Molecular function | molecular adaptor activity |
| GO_0005201 | Molecular function | extracellular matrix structural constituent |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0098640 | Molecular function | integrin binding involved in cell-matrix adhesion |
| GO_0005515 | Molecular function | protein binding |
| Gene name | EMILIN1 |
| Protein name | EMILIN-1 (Elastin microfibril interface-located protein 1) (Elastin microfibril interfacer 1) Elastin microfibril interfacer 1 |
| Synonyms | EMI |
| Description | FUNCTION: May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity. |
| Accessions | A0A0A0MT20 ENST00000433140.1 ENST00000380320.9 [Q9Y6C2-1] Q9Y6C2 |
