Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 17 studies | 28% ± 11% | |
| astrocyte | 15 studies | 44% ± 19% | |
| oligodendrocyte precursor cell | 12 studies | 35% ± 15% | |
| glutamatergic neuron | 10 studies | 42% ± 24% | |
| microglial cell | 10 studies | 24% ± 9% | |
| oligodendrocyte | 10 studies | 31% ± 10% | |
| adipocyte | 9 studies | 23% ± 7% | |
| GABAergic neuron | 8 studies | 41% ± 21% | |
| macrophage | 7 studies | 29% ± 7% | |
| epithelial cell | 6 studies | 28% ± 19% | |
| interneuron | 6 studies | 41% ± 22% | |
| retina horizontal cell | 6 studies | 51% ± 22% | |
| Mueller cell | 6 studies | 39% ± 17% | |
| fibroblast | 6 studies | 21% ± 2% | |
| pericyte | 6 studies | 18% ± 2% | |
| amacrine cell | 5 studies | 54% ± 19% | |
| endothelial cell of lymphatic vessel | 5 studies | 20% ± 3% | |
| type I pneumocyte | 5 studies | 29% ± 6% | |
| neuron | 4 studies | 31% ± 12% | |
| granule cell | 4 studies | 44% ± 13% | |
| cardiac muscle cell | 4 studies | 24% ± 1% | |
| retinal ganglion cell | 4 studies | 48% ± 23% | |
| retinal rod cell | 4 studies | 23% ± 6% | |
| dendritic cell | 4 studies | 16% ± 1% | |
| monocyte | 4 studies | 24% ± 4% | |
| smooth muscle cell | 4 studies | 20% ± 3% | |
| GABAergic interneuron | 3 studies | 25% ± 2% | |
| plasma cell | 3 studies | 26% ± 4% | |
| GABAergic amacrine cell | 3 studies | 50% ± 9% | |
| OFF-bipolar cell | 3 studies | 23% ± 3% | |
| glycinergic amacrine cell | 3 studies | 47% ± 5% | |
| retinal cone cell | 3 studies | 23% ± 8% | |
| myeloid cell | 3 studies | 22% ± 6% | |
| hepatocyte | 3 studies | 32% ± 9% | |
| ependymal cell | 3 studies | 36% ± 16% | |
| T cell | 3 studies | 22% ± 2% | |
| alveolar macrophage | 3 studies | 24% ± 7% | |
| type II pneumocyte | 3 studies | 21% ± 3% | |
| lymphocyte | 3 studies | 24% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 878.80 | 2641 / 2642 | 100% | 2.87 | 702 / 705 |
| esophagus | 100% | 675.98 | 1445 / 1445 | 90% | 1.70 | 164 / 183 |
| breast | 100% | 698.79 | 459 / 459 | 89% | 1.62 | 996 / 1118 |
| intestine | 100% | 633.09 | 966 / 966 | 87% | 1.48 | 461 / 527 |
| stomach | 100% | 490.33 | 359 / 359 | 87% | 1.61 | 249 / 286 |
| uterus | 100% | 689.36 | 170 / 170 | 85% | 1.61 | 391 / 459 |
| prostate | 100% | 502.63 | 245 / 245 | 81% | 1.18 | 407 / 502 |
| ovary | 100% | 623.36 | 180 / 180 | 80% | 1.38 | 346 / 430 |
| kidney | 100% | 599.90 | 89 / 89 | 78% | 1.54 | 705 / 901 |
| lung | 100% | 563.26 | 576 / 578 | 73% | 1.21 | 846 / 1155 |
| bladder | 100% | 642.00 | 21 / 21 | 71% | 1.23 | 359 / 504 |
| pancreas | 100% | 511.45 | 327 / 328 | 67% | 0.94 | 120 / 178 |
| skin | 100% | 771.62 | 1808 / 1809 | 62% | 0.92 | 291 / 472 |
| thymus | 100% | 575.53 | 652 / 653 | 55% | 0.85 | 331 / 605 |
| adrenal gland | 100% | 658.23 | 258 / 258 | 50% | 0.71 | 115 / 230 |
| liver | 100% | 378.14 | 226 / 226 | 32% | 0.45 | 128 / 406 |
| adipose | 100% | 680.38 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 729.33 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 100% | 529.19 | 241 / 241 | 0% | 0 | 0 / 0 |
| muscle | 100% | 447.43 | 800 / 803 | 0% | 0 | 0 / 0 |
| heart | 98% | 486.22 | 840 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 1.59 | 28 / 29 |
| peripheral blood | 88% | 423.75 | 814 / 929 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 82% | 1.46 | 37 / 45 |
| eye | 0% | 0 | 0 / 0 | 46% | 0.60 | 37 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0002098 | Biological process | tRNA wobble uridine modification |
| GO_0006368 | Biological process | transcription elongation by RNA polymerase II |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0006417 | Biological process | regulation of translation |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0008023 | Cellular component | transcription elongation factor complex |
| GO_0033588 | Cellular component | elongator holoenzyme complex |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0000993 | Molecular function | RNA polymerase II complex binding |
| GO_0008607 | Molecular function | phosphorylase kinase regulator activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | ELP4 |
| Protein name | Elongator complex protein 4 (hELP4) (PAX6 neighbor gene protein) Elongator acetyltransferase complex subunit 4 Elongator complex protein 4 |
| Synonyms | Z83307.2-003 PAXNEB hCG_27855 C11orf19 |
| Description | FUNCTION: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) . The elongator complex catalyzes the formation of carboxymethyluridine in the wobble base at position 34 in tRNAs . . |
| Accessions | ENST00000638917.1 A0A1W2PRF0 ENST00000350638.10 ENST00000640342.1 ENST00000639097.1 ENST00000639570.1 ENST00000379163.10 [Q96EB1-3] E9PPJ9 ENST00000474374.5 A0A1W2PP49 A0A1W2PQW5 ENST00000638184.1 A0A1W2PR08 A0A1W2PQA7 A0A1X7SBS0 ENST00000638482.1 A0A1W2PQZ6 A0A1W2PRJ0 ENST00000638376.1 ENST00000640961.2 [Q96EB1-1] A0A1W2PRF5 A0A1W2PNY4 A0A1W2PNW2 ENST00000638347.1 A0A1W2PS93 ENST00000638317.1 B1B1I7 ENST00000638764.1 ENST00000640954.1 A0A1W2PPR3 ENST00000638984.1 A0A1W2PNF7 A0A1W2PP47 G5E9D4 ENST00000639878.1 ENST00000640790.1 ENST00000640081.1 A0A1W2PQ05 ENST00000639182.1 A0A1W2PNY5 A0A1W2PS44 A0A1W2PPP6 ENST00000640231.1 Q96EB1 ENST00000640533.1 ENST00000395934.2 |