Name | Number of supported studies | Average coverage | |
---|---|---|---|
fibroblast | 34 studies | 37% ± 19% | |
endothelial cell of lymphatic vessel | 27 studies | 51% ± 16% | |
astrocyte | 15 studies | 40% ± 20% | |
mesothelial cell | 13 studies | 53% ± 19% | |
basal cell | 12 studies | 31% ± 13% | |
connective tissue cell | 12 studies | 33% ± 11% | |
type I pneumocyte | 11 studies | 44% ± 18% | |
ciliated cell | 10 studies | 26% ± 9% | |
epithelial cell | 8 studies | 27% ± 6% | |
pericyte | 7 studies | 43% ± 22% | |
adipocyte | 6 studies | 31% ± 12% | |
endothelial cell | 5 studies | 26% ± 8% | |
club cell | 5 studies | 25% ± 11% | |
retinal pigment epithelial cell | 5 studies | 52% ± 12% | |
adventitial cell | 5 studies | 67% ± 16% | |
Mueller cell | 5 studies | 29% ± 12% | |
placental villous trophoblast | 3 studies | 77% ± 21% | |
type II pneumocyte | 3 studies | 28% ± 12% | |
smooth muscle cell | 3 studies | 20% ± 3% | |
myoepithelial cell | 3 studies | 44% ± 9% | |
myofibroblast cell | 3 studies | 34% ± 15% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 100% | 18143.46 | 577 / 578 | 88% | 88.88 | 1019 / 1155 |
breast | 98% | 14519.71 | 452 / 459 | 86% | 96.46 | 967 / 1118 |
thymus | 99% | 21277.96 | 649 / 653 | 80% | 61.07 | 484 / 605 |
prostate | 76% | 6825.36 | 186 / 245 | 79% | 37.86 | 395 / 502 |
uterus | 92% | 10784.82 | 157 / 170 | 60% | 77.17 | 277 / 459 |
brain | 50% | 4400.97 | 1326 / 2642 | 97% | 195.10 | 681 / 705 |
ovary | 100% | 19190.69 | 180 / 180 | 47% | 22.67 | 201 / 430 |
bladder | 95% | 15959.71 | 20 / 21 | 51% | 48.55 | 255 / 504 |
kidney | 61% | 5015.17 | 54 / 89 | 62% | 72.18 | 557 / 901 |
skin | 82% | 16883.92 | 1483 / 1809 | 35% | 15.15 | 166 / 472 |
adrenal gland | 70% | 5694.32 | 180 / 258 | 46% | 28.78 | 106 / 230 |
esophagus | 55% | 5363.31 | 798 / 1445 | 59% | 49.24 | 108 / 183 |
stomach | 46% | 3558.93 | 164 / 359 | 62% | 44.30 | 178 / 286 |
intestine | 55% | 5213.81 | 534 / 966 | 51% | 30.45 | 267 / 527 |
blood vessel | 100% | 75005.12 | 1335 / 1335 | 0% | 0 | 0 / 0 |
adipose | 100% | 25911.02 | 1202 / 1204 | 0% | 0 | 0 / 0 |
pancreas | 11% | 574.75 | 37 / 328 | 87% | 92.99 | 155 / 178 |
tonsil | 0% | 0 | 0 / 0 | 82% | 39.13 | 37 / 45 |
heart | 64% | 10077.64 | 547 / 861 | 0% | 0 | 0 / 0 |
spleen | 54% | 3363.88 | 131 / 241 | 0% | 0 | 0 / 0 |
liver | 5% | 363.41 | 12 / 226 | 40% | 24.96 | 161 / 406 |
lymph node | 0% | 0 | 0 / 0 | 38% | 13.31 | 11 / 29 |
eye | 0% | 0 | 0 / 0 | 24% | 8.90 | 19 / 80 |
muscle | 4% | 280.42 | 33 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 1% | 28.12 | 5 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007601 | Biological process | visual perception |
GO_0032331 | Biological process | negative regulation of chondrocyte differentiation |
GO_0018108 | Biological process | peptidyl-tyrosine phosphorylation |
GO_0048050 | Biological process | post-embryonic eye morphogenesis |
GO_0006355 | Biological process | regulation of DNA-templated transcription |
GO_0007173 | Biological process | epidermal growth factor receptor signaling pathway |
GO_0043010 | Biological process | camera-type eye development |
GO_0048048 | Biological process | embryonic eye morphogenesis |
GO_0005615 | Cellular component | extracellular space |
GO_0005576 | Cellular component | extracellular region |
GO_0070062 | Cellular component | extracellular exosome |
GO_0062023 | Cellular component | collagen-containing extracellular matrix |
GO_0031012 | Cellular component | extracellular matrix |
GO_0005006 | Molecular function | epidermal growth factor receptor activity |
GO_0005201 | Molecular function | extracellular matrix structural constituent |
GO_0005154 | Molecular function | epidermal growth factor receptor binding |
GO_0008083 | Molecular function | growth factor activity |
GO_0005509 | Molecular function | calcium ion binding |
GO_0005515 | Molecular function | protein binding |
Gene name | EFEMP1 |
Protein name | EGF containing fibulin-like extracellular matrix protein 1 isoform 2 (HCG16977, isoform CRA_b) EGF containing fibulin extracellular matrix protein 1 EGF containing fibulin-like extracellular matrix protein 1 isoform 1 EGF-containing fibulin-like extracellular matrix protein 1 (Extracellular protein S1-5) (Fibrillin-like protein) (Fibulin-3) (FIBL-3) Uncharacterized protein EFEMP1 |
Synonyms | hCG_16977 FBNL FBLN3 |
Description | FUNCTION: Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth. . |
Accessions | C9JQX7 ENST00000355426.8 [Q12805-1] ENST00000424207.5 ENST00000429909.5 ENST00000421664.1 ENST00000452337.5 C9J4J8 Q580Q6 ENST00000394555.6 [Q12805-1] ENST00000440439.5 C9JUM4 A0A0S2Z3V1 ENST00000634374.1 C9JPZ9 C9J4H7 Q53TA7 A0A0S2Z4F1 C9J8S9 ENST00000635671.1 ENST00000438672.5 Q12805 A0A0U1RRL0 ENST00000439193.5 A0A0U1RQV3 |