Name | Number of supported studies | Average coverage | |
---|---|---|---|
pericyte | 35 studies | 47% ± 20% | |
endothelial cell | 30 studies | 38% ± 20% | |
fibroblast | 27 studies | 37% ± 20% | |
B cell | 25 studies | 32% ± 18% | |
smooth muscle cell | 22 studies | 41% ± 21% | |
memory B cell | 11 studies | 19% ± 2% | |
adipocyte | 11 studies | 86% ± 15% | |
naive B cell | 7 studies | 21% ± 4% | |
capillary endothelial cell | 7 studies | 27% ± 17% | |
vein endothelial cell | 7 studies | 29% ± 25% | |
retinal ganglion cell | 7 studies | 79% ± 25% | |
connective tissue cell | 6 studies | 32% ± 13% | |
precursor B cell | 6 studies | 41% ± 11% | |
astrocyte | 6 studies | 47% ± 16% | |
endothelial cell of vascular tree | 6 studies | 40% ± 18% | |
endothelial cell of lymphatic vessel | 6 studies | 51% ± 18% | |
GABAergic neuron | 5 studies | 32% ± 14% | |
pro-B cell | 5 studies | 51% ± 11% | |
glutamatergic neuron | 4 studies | 47% ± 26% | |
myofibroblast cell | 4 studies | 33% ± 14% | |
immature B cell | 4 studies | 28% ± 7% | |
progenitor cell | 3 studies | 30% ± 9% | |
endothelial cell of artery | 3 studies | 24% ± 8% | |
granule cell | 3 studies | 43% ± 16% | |
microglial cell | 3 studies | 58% ± 17% | |
oligodendrocyte precursor cell | 3 studies | 28% ± 15% | |
endocardial cell | 3 studies | 58% ± 13% | |
glycinergic amacrine cell | 3 studies | 40% ± 13% | |
adventitial cell | 3 studies | 44% ± 20% | |
mesothelial cell | 3 studies | 64% ± 26% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 5130.92 | 458 / 459 | 89% | 6.68 | 999 / 1118 |
thymus | 98% | 2051.15 | 643 / 653 | 84% | 4.92 | 506 / 605 |
prostate | 87% | 1216.44 | 212 / 245 | 69% | 3.00 | 347 / 502 |
esophagus | 76% | 1331.90 | 1100 / 1445 | 75% | 4.26 | 137 / 183 |
ovary | 94% | 2017.94 | 169 / 180 | 51% | 2.50 | 218 / 430 |
skin | 91% | 1933.81 | 1649 / 1809 | 51% | 2.95 | 243 / 472 |
lung | 88% | 1043.08 | 511 / 578 | 54% | 2.61 | 619 / 1155 |
uterus | 99% | 3039.16 | 169 / 170 | 36% | 4.25 | 166 / 459 |
bladder | 100% | 2565.57 | 21 / 21 | 33% | 1.78 | 165 / 504 |
kidney | 62% | 646.94 | 55 / 89 | 67% | 10.20 | 600 / 901 |
adrenal gland | 36% | 298.90 | 93 / 258 | 90% | 11.65 | 208 / 230 |
brain | 35% | 590.56 | 932 / 2642 | 87% | 5.99 | 616 / 705 |
intestine | 77% | 1185.93 | 743 / 966 | 33% | 2.13 | 175 / 527 |
stomach | 41% | 608.33 | 147 / 359 | 59% | 4.60 | 169 / 286 |
adipose | 100% | 7131.80 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 5070.52 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 97% | 15.33 | 28 / 29 |
spleen | 95% | 1068.55 | 229 / 241 | 0% | 0 | 0 / 0 |
heart | 89% | 1113.99 | 762 / 861 | 0% | 0 | 0 / 0 |
pancreas | 5% | 38.91 | 18 / 328 | 83% | 5.07 | 147 / 178 |
tonsil | 0% | 0 | 0 / 0 | 64% | 3.74 | 29 / 45 |
muscle | 51% | 464.34 | 412 / 803 | 0% | 0 | 0 / 0 |
liver | 0% | 0 | 0 / 226 | 26% | 1.17 | 105 / 406 |
peripheral blood | 19% | 493.14 | 177 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 16% | 0.51 | 13 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0000785 | Cellular component | chromatin |
GO_0005634 | Cellular component | nucleus |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0005515 | Molecular function | protein binding |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
GO_0046872 | Molecular function | metal ion binding |
Gene name | EBF1 |
Protein name | EBF transcription factor 1 Transcription factor COE1 (O/E-1) (OE-1) (Early B-cell factor) |
Synonyms | EBF COE1 |
Description | FUNCTION: Key pioneer transcription factor of B-cell specification and commitment . Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'. Operates in a transcription factor network to activate B-cell-specific genes and repress genes associated with alternative cell fates. For instance, positively regulates many B-cell specific genes including BCR or CD40 while repressing genes that direct cells into alternative lineages, including GATA3 and TCF7 for the T-cell lineage. In addition to its role during lymphopoiesis, controls the thermogenic gene program in adipocytes during development and in response to environmental cold (By similarity). .; FUNCTION: (Microbial infection) Acts as a chromatin anchor for Epstein-Barr virus EBNA2 to mediate the assembly of EBNA2 chromatin complexes in B-cells . In addition, binds to the viral LMP1 proximal promoter and promotes its expression during latency . . |
Accessions | ENST00000313708.11 [Q9UH73-1] ENST00000380654.8 [Q9UH73-2] ENST00000517373.1 Q9UH73 E5RFQ1 |