EAF2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006915Biological processapoptotic process
GO_0060770Biological processnegative regulation of epithelial cell proliferation involved in prostate gland development
GO_0006368Biological processtranscription elongation by RNA polymerase II
GO_0034243Biological processregulation of transcription elongation by RNA polymerase II
GO_0060767Biological processepithelial cell proliferation involved in prostate gland development
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0030308Biological processnegative regulation of cell growth
GO_0032783Cellular componentsuper elongation complex
GO_0016607Cellular componentnuclear speck
GO_0005654Cellular componentnucleoplasm
GO_0008023Cellular componenttranscription elongation factor complex
GO_0005515Molecular functionprotein binding
GO_0003711Molecular functiontranscription elongation factor activity

IV. Literature review

[source]
Gene nameEAF2
Protein nameELL-associated factor 2 (Testosterone-regulated apoptosis inducer and tumor suppressor protein)
ELL associated factor 2
ELL associated factor 2 (cDNA FLJ60185, highly similar to ELL-associated factor 2)
SynonymsTRAITS
BM-040
DescriptionFUNCTION: Acts as a transcriptional transactivator of TCEA1 elongation activity (By similarity). Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. Potent inducer of apoptosis in prostatic and non-prostatic cell lines. Inhibits prostate tumor growth in vivo. .

AccessionsF8WF04
ENST00000490434.5
F8WCI9
ENST00000273668.7 [Q96CJ1-1]
Q96CJ1
ENST00000490477.1
ENST00000451944.2
B4DWJ3