DYNC2I1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0060271Biological processcilium assembly
GO_0048704Biological processembryonic skeletal system morphogenesis
GO_0035721Biological processintraciliary retrograde transport
GO_0097542Cellular componentciliary tip
GO_0005813Cellular componentcentrosome
GO_0005615Cellular componentextracellular space
GO_0005929Cellular componentcilium
GO_0031021Cellular componentinterphase microtubule organizing center
GO_0000242Cellular componentpericentriolar material
GO_0005868Cellular componentcytoplasmic dynein complex
GO_0000922Cellular componentspindle pole
GO_0005737Cellular componentcytoplasm
GO_0097546Cellular componentciliary base
GO_0045503Molecular functiondynein light chain binding
GO_0005515Molecular functionprotein binding
GO_0045504Molecular functiondynein heavy chain binding

IV. Literature review

[source]
Gene nameDYNC2I1
Protein nameCytoplasmic dynein 2 intermediate chain 1 (Dynein 2 intermediate chain 1) (WD repeat-containing protein 60)
Dynein 2 intermediate chain 1
SynonymsWDR60
DescriptionFUNCTION: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 2 complex (dynein-2 complex), a motor protein complex that drives the movement of cargos along microtubules within cilia and flagella in concert with the intraflagellar transport (IFT) system . DYNC2I1 plays a major role in retrograde ciliary protein trafficking in cilia and flagella . Requires also to maintain a functional transition zone . .

AccessionsH7C022
ENST00000397143.3
ENST00000407559.8
ENST00000454771.1
Q8WVS4
ENST00000444851.5
H7BYQ2
H7C1E8