Name | Number of supported studies | Average coverage | |
---|---|---|---|
lung | 4 studies | 24% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
pancreas | 99% | 3437.64 | 326 / 328 | 93% | 37.11 | 166 / 178 |
breast | 99% | 6447.85 | 453 / 459 | 85% | 102.92 | 954 / 1118 |
skin | 84% | 1125.71 | 1521 / 1809 | 99% | 187.70 | 466 / 472 |
adrenal gland | 100% | 1308.74 | 258 / 258 | 60% | 23.52 | 137 / 230 |
lung | 99% | 1497.63 | 572 / 578 | 54% | 29.10 | 627 / 1155 |
stomach | 83% | 6211.10 | 299 / 359 | 63% | 30.57 | 179 / 286 |
bladder | 67% | 2064.81 | 14 / 21 | 61% | 26.48 | 305 / 504 |
prostate | 87% | 1300.78 | 212 / 245 | 39% | 10.50 | 197 / 502 |
thymus | 45% | 245.21 | 294 / 653 | 72% | 20.22 | 438 / 605 |
adipose | 98% | 3891.34 | 1185 / 1204 | 0% | 0 | 0 / 0 |
intestine | 34% | 224.96 | 333 / 966 | 59% | 27.41 | 309 / 527 |
eye | 0% | 0 | 0 / 0 | 91% | 41.73 | 73 / 80 |
brain | 51% | 589.60 | 1343 / 2642 | 30% | 6.41 | 209 / 705 |
esophagus | 27% | 204.82 | 384 / 1445 | 52% | 30.55 | 96 / 183 |
muscle | 62% | 626.36 | 499 / 803 | 0% | 0 | 0 / 0 |
uterus | 21% | 105.24 | 35 / 170 | 40% | 16.89 | 184 / 459 |
lymph node | 0% | 0 | 0 / 0 | 52% | 12.40 | 15 / 29 |
kidney | 24% | 163.76 | 21 / 89 | 23% | 4.48 | 203 / 901 |
tonsil | 0% | 0 | 0 / 0 | 42% | 10.91 | 19 / 45 |
peripheral blood | 36% | 3546.85 | 334 / 929 | 0% | 0 | 0 / 0 |
blood vessel | 32% | 325.83 | 430 / 1335 | 0% | 0 | 0 / 0 |
heart | 28% | 207.71 | 244 / 861 | 0% | 0 | 0 / 0 |
ovary | 4% | 17.79 | 7 / 180 | 17% | 3.66 | 73 / 430 |
spleen | 14% | 76.11 | 34 / 241 | 0% | 0 | 0 / 0 |
liver | 1% | 8.02 | 3 / 226 | 9% | 2.64 | 36 / 406 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0043409 | Biological process | negative regulation of MAPK cascade |
GO_0001706 | Biological process | endoderm formation |
GO_0070373 | Biological process | negative regulation of ERK1 and ERK2 cascade |
GO_0035335 | Biological process | peptidyl-tyrosine dephosphorylation |
GO_0016311 | Biological process | dephosphorylation |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0017017 | Molecular function | MAP kinase tyrosine/serine/threonine phosphatase activity |
GO_0016791 | Molecular function | phosphatase activity |
GO_1990439 | Molecular function | MAP kinase serine/threonine phosphatase activity |
GO_0004725 | Molecular function | protein tyrosine phosphatase activity |
GO_0017018 | Molecular function | myosin phosphatase activity |
GO_0008330 | Molecular function | protein tyrosine/threonine phosphatase activity |
GO_0033550 | Molecular function | MAP kinase tyrosine phosphatase activity |
GO_0005515 | Molecular function | protein binding |
Gene name | DUSP4 |
Protein name | Dual specificity protein phosphatase 4 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase hVH2) (Mitogen-activated protein kinase phosphatase 2) (MAP kinase phosphatase 2) (MKP-2) |
Synonyms | VH2 MKP2 |
Description | FUNCTION: Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2. . |
Accessions | ENST00000240101.2 [Q13115-2] Q13115 ENST00000240100.7 [Q13115-1] |