DTNB report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0099536Biological processsynaptic signaling
GO_0030182Biological processneuron differentiation
GO_0014069Cellular componentpostsynaptic density
GO_0009925Cellular componentbasal plasma membrane
GO_0060077Cellular componentinhibitory synapse
GO_0030425Cellular componentdendrite
GO_0045202Cellular componentsynapse
GO_0005886Cellular componentplasma membrane
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding
GO_0008270Molecular functionzinc ion binding

IV. Literature review

[source]
Gene nameDTNB
Protein nameDystrobrevin
Uncharacterized protein DTNB
Dystrobrevin beta (DTN-B) (Beta-dystrobrevin)
Dystrobrevin beta
Synonyms
DescriptionFUNCTION: Scaffolding protein that assembles DMD and SNTA1 molecules to the basal membrane of kidney cells and liver sinusoids (By similarity). May function as a repressor of the SYN1 promoter through the binding of repressor element-1 (RE-1), in turn regulates SYN1 expression and may be involved in cell proliferation regulation during the early phase of neural differentiation . May be required for proper maturation and function of a subset of inhibitory synapses (By similarity). .

AccessionsENST00000404103.7 [O60941-4]
Q53SF9
E9PE76
F8WD22
O60941
Q53T51
ENST00000288642.12
E7EVB6
E9PEY4
ENST00000398951.6
Q53TC8
ENST00000405222.5 [O60941-5]
E7ES64
ENST00000407661.7 [O60941-7]
ENST00000407038.7 [O60941-2]
ENST00000406818.8 [O60941-1]
Q53QV1
ENST00000349996.6
ENST00000356599.9
ENST00000303659.8
Q1I0L3
F8W9U0
ENST00000407186.5