DSCAML1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007409Biological processaxonogenesis
GO_0007420Biological processbrain development
GO_0048704Biological processembryonic skeletal system morphogenesis
GO_0007156Biological processhomophilic cell adhesion via plasma membrane adhesion molecules
GO_0001709Biological processcell fate determination
GO_0007411Biological processaxon guidance
GO_0070593Biological processdendrite self-avoidance
GO_0009953Biological processdorsal/ventral pattern formation
GO_0007417Biological processcentral nervous system development
GO_0005615Cellular componentextracellular space
GO_0009986Cellular componentcell surface
GO_0030424Cellular componentaxon
GO_0045202Cellular componentsynapse
GO_0005886Cellular componentplasma membrane
GO_0042803Molecular functionprotein homodimerization activity
GO_0098632Molecular functioncell-cell adhesion mediator activity

IV. Literature review

[source]
Gene nameDSCAML1
Protein nameDS cell adhesion molecule like 1 (Down syndrome cell adhesion molecule like 1, isoform CRA_b)
Cell adhesion molecule DSCAML1 (Down syndrome cell adhesion molecule 2) (Down syndrome cell adhesion molecule-like protein 1)
DS cell adhesion molecule like 1
SynonymshCG_1810968
KIAA1132
DSCAM2
DescriptionFUNCTION: Cell adhesion molecule that plays a role in neuronal self-avoidance . Promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Promotes both isoneuronal self-avoidance for creating an orderly neurite arborization in retinal rod bipolar cells and heteroneuronal self-avoidance to maintain mosaic spacing between AII amacrine cells (By similarity). Adhesion molecule that promotes lamina-specific synaptic connections in the retina: expressed in specific subsets of interneurons and retinal ganglion cells (RGCs) and promotes synaptic connectivity via homophilic interactions (By similarity). .

AccessionsENST00000525836.1
A0A384DVL8
E9PP71
ENST00000651296.2 [Q8TD84-1]
Q8TD84
ENST00000651172.1
ENST00000527706.5 [Q8TD84-2]
ENST00000321322.6