Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell of lymphatic vessel | 17 studies | 46% ± 24% | |
oligodendrocyte | 15 studies | 75% ± 15% | |
non-classical monocyte | 12 studies | 25% ± 11% | |
macrophage | 12 studies | 37% ± 17% | |
astrocyte | 11 studies | 38% ± 19% | |
fibroblast | 11 studies | 25% ± 10% | |
mast cell | 11 studies | 31% ± 10% | |
type I pneumocyte | 9 studies | 39% ± 19% | |
monocyte | 8 studies | 36% ± 18% | |
endothelial cell | 8 studies | 32% ± 20% | |
neutrophil | 7 studies | 19% ± 4% | |
myeloid cell | 7 studies | 38% ± 16% | |
epithelial cell | 7 studies | 43% ± 17% | |
dendritic cell | 7 studies | 34% ± 12% | |
smooth muscle cell | 6 studies | 31% ± 16% | |
classical monocyte | 6 studies | 22% ± 8% | |
oligodendrocyte precursor cell | 6 studies | 43% ± 10% | |
ciliated cell | 6 studies | 26% ± 9% | |
microglial cell | 6 studies | 37% ± 16% | |
basal cell | 6 studies | 42% ± 23% | |
club cell | 5 studies | 29% ± 4% | |
type II pneumocyte | 5 studies | 37% ± 5% | |
cholangiocyte | 4 studies | 56% ± 21% | |
hepatocyte | 4 studies | 56% ± 27% | |
cardiac muscle cell | 4 studies | 47% ± 9% | |
glial cell | 4 studies | 39% ± 22% | |
mononuclear phagocyte | 4 studies | 26% ± 8% | |
respiratory goblet cell | 4 studies | 42% ± 11% | |
Schwann cell | 4 studies | 56% ± 22% | |
extravillous trophoblast | 3 studies | 38% ± 20% | |
Mueller cell | 3 studies | 21% ± 3% | |
lymphocyte | 3 studies | 23% ± 4% | |
neuron | 3 studies | 32% ± 23% | |
retinal pigment epithelial cell | 3 studies | 46% ± 12% | |
alveolar macrophage | 3 studies | 31% ± 9% | |
pericyte | 3 studies | 22% ± 4% | |
transit amplifying cell | 3 studies | 42% ± 37% | |
GABAergic neuron | 3 studies | 24% ± 2% | |
mucus secreting cell | 3 studies | 31% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 4238.53 | 244 / 245 | 100% | 9.22 | 501 / 502 |
esophagus | 98% | 2384.46 | 1410 / 1445 | 99% | 14.42 | 181 / 183 |
intestine | 100% | 3973.28 | 964 / 966 | 97% | 9.53 | 509 / 527 |
stomach | 99% | 2636.57 | 355 / 359 | 97% | 11.37 | 278 / 286 |
lung | 100% | 4839.00 | 577 / 578 | 95% | 9.77 | 1093 / 1155 |
thymus | 100% | 8536.75 | 653 / 653 | 91% | 8.18 | 552 / 605 |
kidney | 97% | 1825.19 | 86 / 89 | 93% | 6.47 | 838 / 901 |
breast | 94% | 2169.32 | 432 / 459 | 95% | 8.11 | 1058 / 1118 |
bladder | 95% | 2019.10 | 20 / 21 | 89% | 6.38 | 449 / 504 |
skin | 100% | 3395.71 | 1803 / 1809 | 83% | 6.41 | 391 / 472 |
uterus | 95% | 1837.54 | 162 / 170 | 85% | 6.13 | 390 / 459 |
pancreas | 82% | 1248.87 | 269 / 328 | 96% | 12.12 | 170 / 178 |
liver | 100% | 3874.73 | 226 / 226 | 71% | 4.59 | 289 / 406 |
ovary | 100% | 3381.30 | 180 / 180 | 64% | 3.04 | 274 / 430 |
adrenal gland | 96% | 1614.50 | 247 / 258 | 57% | 3.37 | 132 / 230 |
brain | 80% | 2395.82 | 2101 / 2642 | 68% | 4.41 | 479 / 705 |
spleen | 100% | 9852.02 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 2.67 | 1 / 1 |
blood vessel | 100% | 5123.49 | 1329 / 1335 | 0% | 0 | 0 / 0 |
adipose | 96% | 2111.68 | 1154 / 1204 | 0% | 0 | 0 / 0 |
heart | 90% | 2028.34 | 776 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 89% | 4.72 | 40 / 45 |
peripheral blood | 82% | 6347.09 | 759 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 48% | 1.97 | 38 / 80 |
muscle | 36% | 499.42 | 293 / 803 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 17% | 0.64 | 5 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_1904694 | Biological process | negative regulation of vascular associated smooth muscle contraction |
GO_0071800 | Biological process | podosome assembly |
GO_0046849 | Biological process | bone remodeling |
GO_0016601 | Biological process | Rac protein signal transduction |
GO_1900026 | Biological process | positive regulation of substrate adhesion-dependent cell spreading |
GO_0007520 | Biological process | myoblast fusion |
GO_0016477 | Biological process | cell migration |
GO_0010634 | Biological process | positive regulation of epithelial cell migration |
GO_1904754 | Biological process | positive regulation of vascular associated smooth muscle cell migration |
GO_0005886 | Cellular component | plasma membrane |
GO_0002102 | Cellular component | podosome |
GO_0005829 | Cellular component | cytosol |
GO_0070161 | Cellular component | anchoring junction |
GO_0005737 | Cellular component | cytoplasm |
GO_0042995 | Cellular component | cell projection |
GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
GO_0031267 | Molecular function | small GTPase binding |
GO_0005096 | Molecular function | GTPase activator activity |
GO_0005515 | Molecular function | protein binding |
Gene name | DOCK5 |
Protein name | DOCK5 Dedicator of cytokinesis protein 5 Dedicator of cytokinesis 5 |
Synonyms | |
Description | FUNCTION: Guanine nucleotide exchange factor (GEF) for Rho and Rac. GEF proteins activate small GTPases by exchanging bound GDP for free GTP (By similarity). Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen . . |
Accessions | H0YB14 ENST00000467709.6 B9A015 A0A2X0SFZ7 ENST00000410074.5 ENST00000276440.12 [Q9H7D0-1] H0Y7N4 ENST00000444569.5 ENST00000481100.5 [Q9H7D0-2] Q9H7D0 |