CXCL11 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of CXCL11 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	87%	180.68	502 / 578	60%	18.32	691 / 1155
pancreas	96%	201.00	315 / 328	48%	11.09	86 / 178
prostate	67%	290.09	164 / 245	74%	17.80	370 / 502
breast	40%	31.46	184 / 459	73%	30.42	812 / 1118
intestine	37%	28.30	353 / 966	70%	30.25	367 / 527
kidney	61%	47.17	54 / 89	44%	10.43	398 / 901
stomach	38%	39.99	136 / 359	67%	35.58	191 / 286
spleen	96%	119.78	232 / 241	0%	0	0 / 0
esophagus	26%	34.95	372 / 1445	63%	25.38	115 / 183
ovary	13%	4.79	24 / 180	73%	25.63	312 / 430
uterus	21%	17.99	35 / 170	62%	48.01	286 / 459
bladder	29%	12.38	6 / 21	53%	40.73	268 / 504
tonsil	0%	0	0 / 0	80%	71.66	36 / 45
lymph node	0%	0	0 / 0	79%	38.98	23 / 29
brain	61%	152.00	1608 / 2642	18%	3.97	126 / 705
thymus	46%	43.94	300 / 653	28%	5.34	170 / 605
skin	19%	12.29	345 / 1809	51%	16.91	241 / 472
adipose	53%	72.20	641 / 1204	0%	0	0 / 0
liver	20%	8.00	45 / 226	28%	4.91	114 / 406
blood vessel	39%	25.57	515 / 1335	0%	0	0 / 0
heart	30%	23.76	258 / 861	0%	0	0 / 0
muscle	23%	7.42	186 / 803	0%	0	0 / 0
adrenal gland	19%	8.44	49 / 258	4%	1.09	9 / 230
eye	0%	0	0 / 0	5%	0.53	4 / 80
peripheral blood	4%	0.97	37 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0006954	Biological process	inflammatory response
GO_0007165	Biological process	signal transduction
GO_0030593	Biological process	neutrophil chemotaxis
GO_0006935	Biological process	chemotaxis
GO_0007267	Biological process	cell-cell signaling
GO_0070098	Biological process	chemokine-mediated signaling pathway
GO_0007189	Biological process	adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0071222	Biological process	cellular response to lipopolysaccharide
GO_0051281	Biological process	positive regulation of release of sequestered calcium ion into cytosol
GO_0061844	Biological process	antimicrobial humoral immune response mediated by antimicrobial peptide
GO_0010818	Biological process	T cell chemotaxis
GO_0042127	Biological process	regulation of cell population proliferation
GO_0005615	Cellular component	extracellular space
GO_0005576	Cellular component	extracellular region
GO_0008201	Molecular function	heparin binding
GO_0048248	Molecular function	CXCR3 chemokine receptor binding
GO_0008009	Molecular function	chemokine activity
GO_0045236	Molecular function	CXCR chemokine receptor binding
GO_0005515	Molecular function	protein binding

Gene name	CXCL11
Protein name	C-X-C motif chemokine 11 (Beta-R1) (H174) (Interferon gamma-inducible protein 9) (IP-9) (Interferon-inducible T-cell alpha chemoattractant) (I-TAC) (Small-inducible cytokine B11) Alternative protein CXCL11
Synonyms	SCYB9B SCYB11 ITAC
Description	FUNCTION: Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses.
Accessions	ENST00000503860.1 ENST00000306621.8 O14625 L8E879

CXCL11 report