CRIM1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0030514Biological processnegative regulation of BMP signaling pathway
GO_0007399Biological processnervous system development
GO_0045668Biological processnegative regulation of osteoblast differentiation
GO_0048009Biological processinsulin-like growth factor receptor signaling pathway
GO_0005576Cellular componentextracellular region
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0005010Molecular functioninsulin-like growth factor receptor activity
GO_0030165Molecular functionPDZ domain binding
GO_0004867Molecular functionserine-type endopeptidase inhibitor activity

IV. Literature review

[source]
Gene nameCRIM1
Protein nameCysteine-rich motor neuron 1 protein
Cysteine rich transmembrane BMP regulator 1
Uncharacterized protein CRIM1
Cysteine-rich motor neuron 1 protein (CRIM-1) (Cysteine-rich repeat-containing protein S52) [Cleaved into: Processed cysteine-rich motor neuron 1 protein]
SynonymsUNQ1886/PRO4330
S52
DescriptionFUNCTION: May play a role in CNS development by interacting with growth factors implicated in motor neuron differentiation and survival. May play a role in capillary formation and maintenance during angiogenesis. Modulates BMP activity by affecting its processing and delivery to the cell surface. .

AccessionsENST00000619072.1
H7C1Z0
ENST00000619935.1
A0A0G2JN95
ENST00000413985.1
ENST00000428774.1
ENST00000426856.1
Q53TH9
H7C458
ENST00000613124.1
A0A0G2JN98
H7C2T6
Q4ZG85
ENST00000280527.7
Q9NZV1
Q53TR0