Name | Number of supported studies | Average coverage | |
---|---|---|---|
macrophage | 24 studies | 29% ± 8% | |
plasmacytoid dendritic cell | 18 studies | 37% ± 11% | |
endothelial cell | 17 studies | 26% ± 12% | |
smooth muscle cell | 17 studies | 25% ± 6% | |
endothelial cell of lymphatic vessel | 16 studies | 28% ± 11% | |
fibroblast | 16 studies | 20% ± 4% | |
classical monocyte | 15 studies | 24% ± 10% | |
oligodendrocyte | 11 studies | 28% ± 9% | |
monocyte | 10 studies | 26% ± 11% | |
oligodendrocyte precursor cell | 10 studies | 30% ± 10% | |
myeloid cell | 10 studies | 32% ± 13% | |
adipocyte | 9 studies | 25% ± 4% | |
dendritic cell | 9 studies | 30% ± 12% | |
alveolar macrophage | 8 studies | 51% ± 13% | |
non-classical monocyte | 8 studies | 23% ± 9% | |
astrocyte | 7 studies | 25% ± 7% | |
microglial cell | 7 studies | 27% ± 10% | |
pericyte | 7 studies | 20% ± 4% | |
platelet | 7 studies | 25% ± 8% | |
epithelial cell | 7 studies | 27% ± 10% | |
basal cell | 7 studies | 24% ± 12% | |
type I pneumocyte | 7 studies | 23% ± 5% | |
GABAergic neuron | 7 studies | 36% ± 15% | |
conventional dendritic cell | 6 studies | 30% ± 15% | |
myofibroblast cell | 6 studies | 32% ± 8% | |
interneuron | 6 studies | 36% ± 19% | |
glutamatergic neuron | 5 studies | 39% ± 15% | |
cardiac muscle cell | 5 studies | 21% ± 5% | |
mononuclear phagocyte | 5 studies | 25% ± 8% | |
endothelial cell of vascular tree | 5 studies | 23% ± 11% | |
neuron | 4 studies | 30% ± 8% | |
megakaryocyte | 4 studies | 41% ± 15% | |
B cell | 4 studies | 19% ± 4% | |
muscle cell | 4 studies | 39% ± 20% | |
connective tissue cell | 4 studies | 17% ± 1% | |
hematopoietic precursor cell | 3 studies | 23% ± 5% | |
GABAergic interneuron | 3 studies | 20% ± 5% | |
glial cell | 3 studies | 29% ± 8% | |
granule cell | 3 studies | 17% ± 2% | |
progenitor cell | 3 studies | 31% ± 14% | |
mesothelial cell | 3 studies | 19% ± 2% | |
vein endothelial cell | 3 studies | 36% ± 28% | |
abnormal cell | 3 studies | 29% ± 6% | |
transit amplifying cell | 3 studies | 31% ± 19% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 13822.82 | 1445 / 1445 | 100% | 86.80 | 183 / 183 |
skin | 100% | 15355.97 | 1808 / 1809 | 100% | 124.85 | 472 / 472 |
lung | 100% | 12407.51 | 578 / 578 | 100% | 94.21 | 1153 / 1155 |
uterus | 100% | 16153.75 | 170 / 170 | 100% | 87.89 | 457 / 459 |
intestine | 100% | 15736.60 | 966 / 966 | 99% | 75.32 | 524 / 527 |
breast | 100% | 7344.78 | 459 / 459 | 99% | 61.72 | 1108 / 1118 |
bladder | 100% | 13690.43 | 21 / 21 | 96% | 67.10 | 483 / 504 |
adrenal gland | 98% | 4822.45 | 253 / 258 | 96% | 48.41 | 221 / 230 |
brain | 91% | 3676.68 | 2415 / 2642 | 100% | 139.62 | 704 / 705 |
prostate | 98% | 7153.30 | 239 / 245 | 93% | 32.59 | 465 / 502 |
ovary | 99% | 5614.21 | 178 / 180 | 91% | 30.65 | 390 / 430 |
stomach | 83% | 7255.36 | 299 / 359 | 100% | 69.39 | 285 / 286 |
thymus | 78% | 2649.01 | 512 / 653 | 95% | 36.43 | 574 / 605 |
kidney | 69% | 2817.40 | 61 / 89 | 94% | 80.49 | 850 / 901 |
liver | 72% | 2665.45 | 162 / 226 | 90% | 34.79 | 366 / 406 |
pancreas | 16% | 467.75 | 52 / 328 | 98% | 63.98 | 174 / 178 |
adipose | 100% | 9831.67 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 17739.77 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 4555.82 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 92.88 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 35.09 | 1 / 1 |
lymph node | 0% | 0 | 0 / 0 | 97% | 67.43 | 28 / 29 |
eye | 0% | 0 | 0 / 0 | 91% | 44.19 | 73 / 80 |
heart | 88% | 3830.25 | 755 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 85% | 6886.37 | 788 / 929 | 0% | 0 | 0 / 0 |
muscle | 82% | 3051.60 | 659 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_2000394 | Biological process | positive regulation of lamellipodium morphogenesis |
GO_0001755 | Biological process | neural crest cell migration |
GO_0044387 | Biological process | negative regulation of protein kinase activity by regulation of protein phosphorylation |
GO_0090630 | Biological process | activation of GTPase activity |
GO_0045184 | Biological process | establishment of protein localization |
GO_0007165 | Biological process | signal transduction |
GO_0051895 | Biological process | negative regulation of focal adhesion assembly |
GO_0001932 | Biological process | regulation of protein phosphorylation |
GO_0090148 | Biological process | membrane fission |
GO_0001933 | Biological process | negative regulation of protein phosphorylation |
GO_0021591 | Biological process | ventricular system development |
GO_0016197 | Biological process | endosomal transport |
GO_0097750 | Biological process | endosome membrane tubulation |
GO_1900024 | Biological process | regulation of substrate adhesion-dependent cell spreading |
GO_0007015 | Biological process | actin filament organization |
GO_0051893 | Biological process | regulation of focal adhesion assembly |
GO_0006909 | Biological process | phagocytosis |
GO_0022038 | Biological process | corpus callosum development |
GO_1900025 | Biological process | negative regulation of substrate adhesion-dependent cell spreading |
GO_0010762 | Biological process | regulation of fibroblast migration |
GO_0010633 | Biological process | negative regulation of epithelial cell migration |
GO_0010632 | Biological process | regulation of epithelial cell migration |
GO_1900027 | Biological process | regulation of ruffle assembly |
GO_0140285 | Biological process | endosome fission |
GO_0032587 | Cellular component | ruffle membrane |
GO_0042383 | Cellular component | sarcolemma |
GO_0016600 | Cellular component | flotillin complex |
GO_0005925 | Cellular component | focal adhesion |
GO_0015629 | Cellular component | actin cytoskeleton |
GO_0030017 | Cellular component | sarcomere |
GO_0045202 | Cellular component | synapse |
GO_0005938 | Cellular component | cell cortex |
GO_0016328 | Cellular component | lateral plasma membrane |
GO_0010008 | Cellular component | endosome membrane |
GO_0030027 | Cellular component | lamellipodium |
GO_0031982 | Cellular component | vesicle |
GO_0051015 | Molecular function | actin filament binding |
GO_0031267 | Molecular function | small GTPase binding |
GO_0005515 | Molecular function | protein binding |
Gene name | CORO1C |
Protein name | Coronin Coronin 1C Coronin-1C (Coronin-3) (hCRNN4) |
Synonyms | CRNN4 CRN2 |
Description | FUNCTION: Plays a role in directed cell migration by regulating the activation and subcellular location of RAC1 . Increases the presence of activated RAC1 at the leading edge of migrating cells . Required for normal organization of the cytoskeleton, including the actin cytoskeleton, microtubules and the vimentin intermediate filaments (By similarity). Plays a role in endoplasmic reticulum-associated endosome fission: localizes to endosome membrane tubules and promotes recruitment of TMCC1, leading to recruitment of the endoplasmic reticulum to endosome tubules for fission . Endosome membrane fission of early and late endosomes is essential to separate regions destined for lysosomal degradation from carriers to be recycled to the plasma membrane . Required for normal cell proliferation, cell migration, and normal formation of lamellipodia (By similarity). Required for normal distribution of mitochondria within cells (By similarity). .; FUNCTION: [Isoform 3]: Involved in myogenic differentiation. . |
Accessions | Q9ULV4 F8VSA4 ENST00000547294.5 ENST00000261401.8 [Q9ULV4-1] ENST00000546571.5 ENST00000550542.5 F8VV53 ENST00000546705.5 F8VVB7 F8VRE9 F8VTT6 ENST00000421578.6 ENST00000552871.5 B4E3S0 ENST00000541050.5 [Q9ULV4-1] ENST00000549772.5 [Q9ULV4-2] F8W1H8 ENST00000420959.6 [Q9ULV4-3] F8VUX3 ENST00000550032.5 ENST00000551550.5 ENST00000551044.1 H0YHL7 |