Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 8 studies | 23% ± 6% | |
naive B cell | 6 studies | 19% ± 2% | |
oligodendrocyte | 6 studies | 25% ± 5% | |
B cell | 5 studies | 21% ± 4% | |
adipocyte | 5 studies | 20% ± 4% | |
fibroblast | 5 studies | 20% ± 3% | |
GABAergic neuron | 5 studies | 30% ± 12% | |
natural killer cell | 4 studies | 17% ± 1% | |
CD16-negative, CD56-bright natural killer cell, human | 4 studies | 17% ± 1% | |
CD4-positive, alpha-beta T cell | 4 studies | 19% ± 2% | |
retinal bipolar neuron | 4 studies | 25% ± 10% | |
microglial cell | 4 studies | 21% ± 2% | |
epithelial cell | 4 studies | 30% ± 5% | |
retinal rod cell | 4 studies | 18% ± 3% | |
astrocyte | 4 studies | 33% ± 7% | |
glutamatergic neuron | 4 studies | 50% ± 23% | |
oligodendrocyte precursor cell | 4 studies | 32% ± 8% | |
macrophage | 4 studies | 18% ± 3% | |
CD16-positive, CD56-dim natural killer cell, human | 3 studies | 18% ± 1% | |
ciliated cell | 3 studies | 22% ± 4% | |
CD8-positive, alpha-beta memory T cell | 3 studies | 16% ± 0% | |
regulatory T cell | 3 studies | 18% ± 2% | |
interneuron | 3 studies | 33% ± 13% | |
neuron | 3 studies | 22% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
thymus | 100% | 3895.60 | 653 / 653 | 100% | 13.17 | 604 / 605 |
prostate | 100% | 3171.12 | 245 / 245 | 100% | 10.54 | 501 / 502 |
breast | 100% | 3255.98 | 459 / 459 | 100% | 9.54 | 1114 / 1118 |
uterus | 100% | 3347.87 | 170 / 170 | 100% | 8.24 | 457 / 459 |
esophagus | 100% | 2366.06 | 1445 / 1445 | 99% | 7.72 | 182 / 183 |
brain | 99% | 4666.55 | 2622 / 2642 | 100% | 11.95 | 705 / 705 |
adrenal gland | 100% | 1870.85 | 258 / 258 | 98% | 5.95 | 226 / 230 |
kidney | 100% | 2116.60 | 89 / 89 | 98% | 13.58 | 884 / 901 |
pancreas | 100% | 2100.52 | 328 / 328 | 98% | 8.21 | 174 / 178 |
bladder | 100% | 2482.14 | 21 / 21 | 96% | 5.62 | 486 / 504 |
lung | 100% | 2332.61 | 576 / 578 | 96% | 6.45 | 1114 / 1155 |
intestine | 100% | 2773.78 | 966 / 966 | 96% | 5.21 | 506 / 527 |
stomach | 100% | 2129.31 | 359 / 359 | 95% | 5.42 | 273 / 286 |
liver | 100% | 1512.64 | 226 / 226 | 93% | 4.48 | 379 / 406 |
ovary | 100% | 3162.17 | 180 / 180 | 93% | 4.79 | 398 / 430 |
skin | 100% | 2311.33 | 1807 / 1809 | 83% | 5.30 | 390 / 472 |
blood vessel | 100% | 2617.96 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 8.73 | 29 / 29 |
muscle | 100% | 2580.54 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 3966.83 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 8.03 | 45 / 45 |
adipose | 100% | 2919.45 | 1203 / 1204 | 0% | 0 | 0 / 0 |
heart | 98% | 1492.65 | 841 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 79% | 1322.95 | 733 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 54% | 3.41 | 43 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0043484 | Biological process | regulation of RNA splicing |
GO_0018108 | Biological process | peptidyl-tyrosine phosphorylation |
GO_0005634 | Cellular component | nucleus |
GO_0004713 | Molecular function | protein tyrosine kinase activity |
GO_0004712 | Molecular function | protein serine/threonine/tyrosine kinase activity |
GO_0004674 | Molecular function | protein serine/threonine kinase activity |
GO_0005515 | Molecular function | protein binding |
GO_0106310 | Molecular function | protein serine kinase activity |
GO_0005524 | Molecular function | ATP binding |
Gene name | CLK4 |
Protein name | CDC like kinase 4 CLK4 protein (cDNA FLJ51841, highly similar to Dual specificity protein kinase CLK4) dual-specificity kinase (EC 2.7.12.1) Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4) CDC like kinase 4 (CLK4 protein) |
Synonyms | DKFZp686A20267 |
Description | FUNCTION: Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates SRSF1 and SRSF3. Required for the regulation of alternative splicing of MAPT/TAU. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells. . |
Accessions | ENST00000522136.5 ENST00000316308.9 Q9HAZ1 E7ES88 E7EWJ6 Q4G0Z5 ENST00000522556.1 Q68D95 B9EG64 Q6P090 ENST00000521621.5 ENST00000520957.1 B7ZL31 |