CFAP298 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0060271Biological processcilium assembly
GO_0003352Biological processregulation of cilium movement
GO_0005929Cellular componentcilium
GO_0005856Cellular componentcytoskeleton
GO_0005829Cellular componentcytosol
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCFAP298
Protein nameChromosome 21 open reading frame 59, isoform CRA_b (Cilia and flagella associated protein 298)
Cilia- and flagella-associated protein 298 (Protein kurly homolog)
Cilia and flagella associated protein 298 (cDNA FLJ20467 fis, clone KAT06638)
Cilia and flagella associated protein 298
SynonymsC21orf48
hCG_401201
C21orf59
DescriptionFUNCTION: Plays a role in motile cilium function, possibly by acting on outer dynein arm assembly . Seems to be important for initiation rather than maintenance of cilium motility (By similarity). Required for correct positioning of the cilium at the apical cell surface, suggesting an additional role in the planar cell polarity (PCP) pathway (By similarity). May suppress canonical Wnt signaling activity (By similarity). .

AccessionsENST00000290155.8
D3DSE6
H7C2R6
Q9NX33
C9J818
C9JX57
ENST00000425336.1
ENST00000382549.8
P57076
ENST00000300260.7
H7C3D9
ENST00000440966.5
ENST00000458138.1
ENST00000431599.1