Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
intestine | 100% | 2534.49 | 962 / 966 | 55% | 1.05 | 292 / 527 |
uterus | 100% | 2175.97 | 170 / 170 | 49% | 0.75 | 227 / 459 |
bladder | 95% | 1758.90 | 20 / 21 | 49% | 0.81 | 249 / 504 |
pancreas | 100% | 1117.69 | 327 / 328 | 36% | 0.51 | 64 / 178 |
brain | 97% | 1096.56 | 2553 / 2642 | 39% | 0.59 | 272 / 705 |
stomach | 99% | 1699.66 | 357 / 359 | 30% | 0.61 | 87 / 286 |
thymus | 100% | 2267.03 | 650 / 653 | 27% | 0.42 | 165 / 605 |
prostate | 99% | 2287.80 | 243 / 245 | 25% | 0.32 | 123 / 502 |
esophagus | 100% | 1721.35 | 1440 / 1445 | 23% | 0.37 | 42 / 183 |
lung | 100% | 2460.52 | 577 / 578 | 19% | 0.26 | 215 / 1155 |
breast | 100% | 1921.37 | 459 / 459 | 17% | 0.25 | 194 / 1118 |
kidney | 100% | 1612.46 | 89 / 89 | 15% | 0.21 | 135 / 901 |
skin | 100% | 1720.46 | 1803 / 1809 | 15% | 0.21 | 72 / 472 |
ovary | 100% | 1878.38 | 180 / 180 | 13% | 0.17 | 54 / 430 |
liver | 100% | 1241.04 | 225 / 226 | 8% | 0.11 | 34 / 406 |
adrenal gland | 100% | 1788.84 | 257 / 258 | 7% | 0.09 | 17 / 230 |
ureter | 0% | 0 | 0 / 0 | 100% | 1.22 | 1 / 1 |
adipose | 100% | 1815.49 | 1200 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 1459.07 | 1330 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 4027.44 | 240 / 241 | 0% | 0 | 0 / 0 |
peripheral blood | 98% | 1472.11 | 913 / 929 | 0% | 0 | 0 / 0 |
muscle | 98% | 1186.45 | 789 / 803 | 0% | 0 | 0 / 0 |
heart | 98% | 904.00 | 844 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 59% | 0.93 | 17 / 29 |
tonsil | 0% | 0 | 0 / 0 | 16% | 0.21 | 7 / 45 |
eye | 0% | 0 | 0 / 0 | 5% | 0.06 | 4 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0050684 | Biological process | regulation of mRNA processing |
GO_0006915 | Biological process | apoptotic process |
GO_0006468 | Biological process | protein phosphorylation |
GO_0000278 | Biological process | mitotic cell cycle |
GO_0001558 | Biological process | regulation of cell growth |
GO_0007346 | Biological process | regulation of mitotic cell cycle |
GO_0006355 | Biological process | regulation of DNA-templated transcription |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0004674 | Molecular function | protein serine/threonine kinase activity |
GO_0106310 | Molecular function | protein serine kinase activity |
GO_0004693 | Molecular function | cyclin-dependent protein serine/threonine kinase activity |
GO_0005524 | Molecular function | ATP binding |
GO_0004672 | Molecular function | protein kinase activity |
Gene name | CDK11A |
Protein name | Cyclin dependent kinase 11A Cyclin-dependent kinase 11A (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 2) (Cell division protein kinase 11A) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L2) |
Synonyms | PITSLREB CDC2L3 CDC2L2 |
Description | FUNCTION: Appears to play multiple roles in cell cycle progression, cytokinesis and apoptosis. The p110 isoforms have been suggested to be involved in pre-mRNA splicing, potentially by phosphorylating the splicing protein SFRS7. The p58 isoform may act as a negative regulator of normal cell cycle progression. . |
Accessions | ENST00000357760.6 ENST00000401096.2 Q5QPR4 Q5QPQ9 ENST00000479362.1 Q9UQ88 ENST00000358779.9 [Q9UQ88-4] ENST00000509982.5 ENST00000460465.5 ENST00000404249.8 [Q9UQ88-2] Q5QPR3 J3KS35 ENST00000378638.6 E9PFJ2 ENST00000378633.5 [Q9UQ88-1] E7ESP2 ENST00000356200.7 |