Insufficient scRNA-seq data for expression of CCR3 at single-cell level.
Insufficient scRNA-seq data for expression of CCR3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
spleen | 94% | 37.05 | 227 / 241 | 0% | 0 | 0 / 0 |
lung | 70% | 16.45 | 403 / 578 | 19% | 0.47 | 225 / 1155 |
peripheral blood | 87% | 258.48 | 806 / 929 | 0% | 0 | 0 / 0 |
bladder | 43% | 6.10 | 9 / 21 | 21% | 0.76 | 107 / 504 |
skin | 64% | 33.06 | 1154 / 1809 | 0% | 0 | 0 / 472 |
muscle | 55% | 29.05 | 440 / 803 | 0% | 0 | 0 / 0 |
thymus | 23% | 2.82 | 151 / 653 | 24% | 0.52 | 146 / 605 |
intestine | 35% | 7.43 | 336 / 966 | 9% | 0.16 | 49 / 527 |
adipose | 24% | 3.69 | 291 / 1204 | 0% | 0 | 0 / 0 |
stomach | 16% | 2.29 | 59 / 359 | 7% | 0.14 | 21 / 286 |
liver | 10% | 1.01 | 23 / 226 | 8% | 0.35 | 32 / 406 |
kidney | 17% | 2.38 | 15 / 89 | 1% | 0.03 | 10 / 901 |
esophagus | 13% | 1.82 | 186 / 1445 | 4% | 0.10 | 8 / 183 |
pancreas | 3% | 0.58 | 10 / 328 | 10% | 0.52 | 18 / 178 |
prostate | 11% | 1.69 | 28 / 245 | 0% | 0 | 0 / 502 |
breast | 7% | 0.72 | 31 / 459 | 4% | 0.08 | 47 / 1118 |
uterus | 1% | 0.09 | 2 / 170 | 7% | 0.16 | 30 / 459 |
blood vessel | 7% | 0.82 | 95 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 7% | 0.21 | 2 / 29 |
ovary | 2% | 0.21 | 4 / 180 | 5% | 0.08 | 20 / 430 |
heart | 4% | 0.45 | 34 / 861 | 0% | 0 | 0 / 0 |
brain | 3% | 0.34 | 79 / 2642 | 0% | 0 | 0 / 705 |
adrenal gland | 1% | 0.06 | 2 / 258 | 0% | 0 | 0 / 230 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007188 | Biological process | adenylate cyclase-modulating G protein-coupled receptor signaling pathway |
GO_0006954 | Biological process | inflammatory response |
GO_0019722 | Biological process | calcium-mediated signaling |
GO_0045766 | Biological process | positive regulation of angiogenesis |
GO_0006935 | Biological process | chemotaxis |
GO_0007155 | Biological process | cell adhesion |
GO_0006968 | Biological process | cellular defense response |
GO_0006955 | Biological process | immune response |
GO_0070098 | Biological process | chemokine-mediated signaling pathway |
GO_0007204 | Biological process | positive regulation of cytosolic calcium ion concentration |
GO_0001938 | Biological process | positive regulation of endothelial cell proliferation |
GO_0060326 | Biological process | cell chemotaxis |
GO_0009897 | Cellular component | external side of plasma membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0005737 | Cellular component | cytoplasm |
GO_0016493 | Molecular function | C-C chemokine receptor activity |
GO_0004950 | Molecular function | chemokine receptor activity |
GO_0019957 | Molecular function | C-C chemokine binding |
GO_0005515 | Molecular function | protein binding |
Gene name | CCR3 |
Protein name | C-C motif chemokine receptor 3 (CC chemokine receptor 3) CC chemokine receptor 3 C-C chemokine receptor type 3 (C C CKR3) (C-C CKR-3) (CC-CKR-3) (CCR-3) (CCR3) (CKR 3) (CKR3) (Eosinophil eotaxin receptor) (CD antigen CD193) |
Synonyms | CMKBR3 |
Description | FUNCTION: Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15 . Subsequently transduces a signal by increasing the intracellular calcium ions level . In addition acts as a possible functional receptor for NARS1 . .; FUNCTION: (Microbial infection) Alternative coreceptor with CD4 for HIV-1 infection. . |
Accessions | ENST00000395940.3 [P51677-1] ENST00000452454.1 Q8TDP7 ENST00000357422.2 [P51677-1] Q8TDP5 P51677 Q8TDP4 ENST00000545097.1 [P51677-2] ENST00000395942.2 [P51677-1] ENST00000457243.1 Q8TDP8 Q96T97 Q96T96 |