CAVIN2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0097320Biological processplasma membrane tubulation
GO_0045121Cellular componentmembrane raft
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0005901Cellular componentcaveola
GO_0005737Cellular componentcytoplasm
GO_0005080Molecular functionprotein kinase C binding
GO_0001786Molecular functionphosphatidylserine binding
GO_0005515Molecular functionprotein binding
GO_0005543Molecular functionphospholipid binding

IV. Literature review

[source]
Gene nameCAVIN2
Protein nameCaveolae-associated protein 2 (Cavin-2) (PS-p68) (Phosphatidylserine-binding protein) (Serum deprivation-response protein)
SynonymsSDPR
DescriptionFUNCTION: Plays an important role in caveolar biogenesis and morphology. Regulates caveolae morphology by inducing membrane curvature within caveolae . Plays a role in caveola formation in a tissue-specific manner. Required for the formation of caveolae in the lung and fat endothelia but not in the heart endothelia. Negatively regulates the size or stability of CAVIN complexes in the lung endothelial cells. May play a role in targeting PRKCA to caveolae (By similarity). .

AccessionsO95810
ENST00000304141.5