Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| astrocyte | 17 studies | 62% ± 21% | |
| glutamatergic neuron | 12 studies | 49% ± 28% | |
| fibroblast | 11 studies | 44% ± 18% | |
| microglial cell | 10 studies | 32% ± 14% | |
| smooth muscle cell | 9 studies | 34% ± 16% | |
| endothelial cell | 9 studies | 26% ± 10% | |
| macrophage | 8 studies | 39% ± 15% | |
| B cell | 7 studies | 29% ± 10% | |
| epithelial cell | 7 studies | 36% ± 16% | |
| mesothelial cell | 7 studies | 44% ± 21% | |
| pericyte | 7 studies | 28% ± 9% | |
| plasma cell | 6 studies | 36% ± 21% | |
| basal cell | 6 studies | 37% ± 23% | |
| ciliated cell | 6 studies | 35% ± 13% | |
| myeloid cell | 6 studies | 37% ± 11% | |
| GABAergic neuron | 6 studies | 40% ± 20% | |
| adipocyte | 5 studies | 24% ± 5% | |
| type II pneumocyte | 5 studies | 40% ± 16% | |
| type I pneumocyte | 5 studies | 53% ± 15% | |
| interneuron | 5 studies | 37% ± 16% | |
| kidney distal convoluted tubule epithelial cell | 4 studies | 23% ± 6% | |
| neuron | 4 studies | 43% ± 22% | |
| cardiac muscle cell | 4 studies | 17% ± 3% | |
| dendritic cell | 4 studies | 38% ± 5% | |
| respiratory goblet cell | 4 studies | 36% ± 15% | |
| brush cell | 4 studies | 43% ± 13% | |
| goblet cell | 4 studies | 39% ± 29% | |
| club cell | 4 studies | 28% ± 7% | |
| monocyte | 4 studies | 24% ± 5% | |
| ON-bipolar cell | 3 studies | 43% ± 21% | |
| amacrine cell | 3 studies | 33% ± 24% | |
| retinal pigment epithelial cell | 3 studies | 41% ± 15% | |
| ependymal cell | 3 studies | 42% ± 11% | |
| renal alpha-intercalated cell | 3 studies | 22% ± 6% | |
| renal principal cell | 3 studies | 34% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 100% | 2285.86 | 576 / 578 | 99% | 18.81 | 1143 / 1155 |
| stomach | 99% | 1155.15 | 355 / 359 | 99% | 26.04 | 284 / 286 |
| esophagus | 99% | 1016.08 | 1425 / 1445 | 99% | 27.44 | 182 / 183 |
| breast | 98% | 1273.38 | 451 / 459 | 99% | 20.53 | 1104 / 1118 |
| ovary | 100% | 1399.01 | 180 / 180 | 95% | 11.38 | 408 / 430 |
| thymus | 100% | 1242.18 | 652 / 653 | 94% | 12.07 | 571 / 605 |
| prostate | 99% | 879.57 | 243 / 245 | 93% | 10.78 | 467 / 502 |
| bladder | 100% | 1426.81 | 21 / 21 | 92% | 15.22 | 463 / 504 |
| uterus | 100% | 1022.01 | 170 / 170 | 91% | 17.70 | 418 / 459 |
| skin | 100% | 1464.86 | 1806 / 1809 | 91% | 20.15 | 428 / 472 |
| kidney | 100% | 1501.34 | 89 / 89 | 90% | 12.78 | 815 / 901 |
| pancreas | 91% | 586.82 | 299 / 328 | 96% | 16.47 | 170 / 178 |
| intestine | 79% | 1454.73 | 764 / 966 | 99% | 26.31 | 522 / 527 |
| brain | 96% | 1713.83 | 2538 / 2642 | 82% | 11.58 | 576 / 705 |
| adrenal gland | 100% | 1248.90 | 258 / 258 | 40% | 3.10 | 93 / 230 |
| blood vessel | 100% | 3244.55 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 5.71 | 1 / 1 |
| adipose | 100% | 1607.95 | 1199 / 1204 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 18.14 | 44 / 45 |
| spleen | 91% | 712.37 | 219 / 241 | 0% | 0 | 0 / 0 |
| heart | 78% | 678.91 | 671 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 71% | 7.15 | 57 / 80 |
| liver | 32% | 143.95 | 73 / 226 | 37% | 4.09 | 150 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 66% | 6.24 | 19 / 29 |
| peripheral blood | 17% | 259.03 | 158 / 929 | 0% | 0 | 0 / 0 |
| muscle | 4% | 17.05 | 32 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0044351 | Biological process | macropinocytosis |
| GO_0046415 | Biological process | urate metabolic process |
| GO_0030838 | Biological process | positive regulation of actin filament polymerization |
| GO_0031529 | Biological process | ruffle organization |
| GO_0051496 | Biological process | positive regulation of stress fiber assembly |
| GO_0030032 | Biological process | lamellipodium assembly |
| GO_2000813 | Biological process | negative regulation of barbed-end actin filament capping |
| GO_0051639 | Biological process | actin filament network formation |
| GO_1902745 | Biological process | positive regulation of lamellipodium organization |
| GO_0051638 | Biological process | barbed-end actin filament uncapping |
| GO_0030335 | Biological process | positive regulation of cell migration |
| GO_0007015 | Biological process | actin filament organization |
| GO_1900026 | Biological process | positive regulation of substrate adhesion-dependent cell spreading |
| GO_0034315 | Biological process | regulation of Arp2/3 complex-mediated actin nucleation |
| GO_0016477 | Biological process | cell migration |
| GO_0031941 | Cellular component | filamentous actin |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016607 | Cellular component | nuclear speck |
| GO_0044354 | Cellular component | macropinosome |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0031252 | Cellular component | cell leading edge |
| GO_0005829 | Cellular component | cytosol |
| GO_0030027 | Cellular component | lamellipodium |
| GO_0044877 | Molecular function | protein-containing complex binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | CARMIL1 |
| Protein name | LRRC16A protein F-actin-uncapping protein LRRC16A (CARMIL homolog) (Capping protein regulator and myosin 1 linker protein 1) (Capping protein, Arp2/3 and myosin-I linker homolog 1) (Capping protein, Arp2/3 and myosin-I linker protein 1) (Leucine-rich repeat-containing protein 16A) Capping protein regulator and myosin 1 linker 1 |
| Synonyms | LRRC16 CARMIL LRRC16A |
| Description | FUNCTION: Cell membrane-cytoskeleton-associated protein that plays a role in the regulation of actin polymerization at the barbed end of actin filaments. Prevents F-actin heterodimeric capping protein (CP) activity at the leading edges of migrating cells, and hence generates uncapped barbed ends and enhances actin polymerization, however, seems unable to nucleate filaments . Plays a role in lamellipodial protrusion formations and cell migration . . |
| Accessions | ENST00000700669.1 ENST00000635618.1 ENST00000329474.7 [Q5VZK9-1] A0A0U1RR91 Q5VZK9 A0A8V8TRE2 ENST00000461945.1 A0A0U1RQQ1 B2RTQ5 Q8IW66 |