Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| B cell | 37 studies | 33% ± 15% | |
| plasmacytoid dendritic cell | 22 studies | 64% ± 18% | |
| naive B cell | 19 studies | 31% ± 10% | |
| memory B cell | 16 studies | 28% ± 8% | |
| glutamatergic neuron | 12 studies | 49% ± 19% | |
| epithelial cell | 8 studies | 25% ± 8% | |
| basal cell | 8 studies | 28% ± 13% | |
| GABAergic neuron | 8 studies | 41% ± 17% | |
| interneuron | 6 studies | 30% ± 8% | |
| dendritic cell | 6 studies | 47% ± 25% | |
| retina horizontal cell | 6 studies | 21% ± 4% | |
| pro-B cell | 5 studies | 43% ± 5% | |
| precursor B cell | 5 studies | 28% ± 6% | |
| neuron | 4 studies | 54% ± 12% | |
| immature B cell | 4 studies | 29% ± 5% | |
| cardiac muscle cell | 4 studies | 22% ± 3% | |
| hematopoietic stem cell | 4 studies | 23% ± 9% | |
| abnormal cell | 4 studies | 27% ± 6% | |
| conventional dendritic cell | 3 studies | 41% ± 27% | |
| smooth muscle cell | 3 studies | 26% ± 3% | |
| GABAergic interneuron | 3 studies | 32% ± 13% | |
| progenitor cell | 3 studies | 30% ± 9% | |
| plasma cell | 3 studies | 34% ± 12% | |
| germinal center B cell | 3 studies | 35% ± 12% | |
| transit amplifying cell | 3 studies | 24% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| intestine | 99% | 1209.60 | 956 / 966 | 82% | 2.86 | 432 / 527 |
| esophagus | 69% | 864.81 | 999 / 1445 | 82% | 5.11 | 150 / 183 |
| bladder | 62% | 206.19 | 13 / 21 | 62% | 2.42 | 311 / 504 |
| prostate | 80% | 678.12 | 197 / 245 | 40% | 0.75 | 199 / 502 |
| stomach | 38% | 268.19 | 138 / 359 | 79% | 2.91 | 225 / 286 |
| pancreas | 73% | 288.42 | 241 / 328 | 35% | 0.75 | 63 / 178 |
| brain | 71% | 1410.09 | 1874 / 2642 | 36% | 0.96 | 251 / 705 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 11.51 | 29 / 29 |
| spleen | 100% | 1735.21 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 7.27 | 45 / 45 |
| skin | 72% | 2241.73 | 1306 / 1809 | 21% | 0.63 | 101 / 472 |
| uterus | 14% | 63.85 | 23 / 170 | 80% | 4.52 | 365 / 459 |
| ovary | 2% | 6.07 | 4 / 180 | 89% | 5.06 | 383 / 430 |
| lung | 10% | 34.50 | 55 / 578 | 72% | 3.80 | 831 / 1155 |
| breast | 35% | 212.35 | 162 / 459 | 31% | 1.41 | 342 / 1118 |
| thymus | 28% | 113.39 | 182 / 653 | 33% | 2.22 | 199 / 605 |
| adrenal gland | 30% | 107.88 | 77 / 258 | 28% | 0.57 | 64 / 230 |
| peripheral blood | 53% | 460.09 | 491 / 929 | 0% | 0 | 0 / 0 |
| heart | 40% | 221.09 | 341 / 861 | 0% | 0 | 0 / 0 |
| kidney | 4% | 14.81 | 4 / 89 | 18% | 0.27 | 159 / 901 |
| eye | 0% | 0 | 0 / 0 | 21% | 0.41 | 17 / 80 |
| liver | 0% | 0 | 0 / 226 | 7% | 0.18 | 29 / 406 |
| adipose | 1% | 7.19 | 12 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 1% | 6.46 | 12 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0.38 | 1 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0016925 | Biological process | protein sumoylation |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0010628 | Biological process | positive regulation of gene expression |
| GO_1903860 | Biological process | negative regulation of dendrite extension |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_1904800 | Biological process | negative regulation of neuron remodeling |
| GO_1905232 | Biological process | cellular response to L-glutamate |
| GO_2000173 | Biological process | negative regulation of branching morphogenesis of a nerve |
| GO_2000171 | Biological process | negative regulation of dendrite development |
| GO_0016514 | Cellular component | SWI/SNF complex |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0098794 | Cellular component | postsynapse |
| GO_0016363 | Cellular component | nuclear matrix |
| GO_0005829 | Cellular component | cytosol |
| GO_0005634 | Cellular component | nucleus |
| GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO_0001227 | Molecular function | DNA-binding transcription repressor activity, RNA polymerase II-specific |
| GO_0019901 | Molecular function | protein kinase binding |
| GO_0003700 | Molecular function | DNA-binding transcription factor activity |
| GO_0046872 | Molecular function | metal ion binding |
| Gene name | BCL11A |
| Protein name | B-cell CLL/lymphoma 11A (Zinc finger protein), isoform CRA_b (BCL11A B-cell CLL/lymphoma 11A (Zinc finger protein) isoform 1) B-cell lymphoma/leukemia 11A (BCL-11A) (B-cell CLL/lymphoma 11A) (COUP-TF-interacting protein 1) (Ecotropic viral integration site 9 protein homolog) (EVI-9) (Zinc finger protein 856) B-cell CLL/lymphoma 11A (Zinc finger protein), isoform CRA_d (BCL11 transcription factor A) B-cell CLL/lymphoma 11A (Zinc finger protein) isoform 2 (B-cell CLL/lymphoma 11A (Zinc finger protein), isoform CRA_c) BCL11 transcription factor A BCL11a-M Uncharacterized protein BCL11A |
| Synonyms | KIAA1809 CTIP1 ZNF856 EVI9 hCG_1986387 |
| Description | FUNCTION: Transcription factor . Associated with the BAF SWI/SNF chromatin remodeling complex . Binds to the 5'-TGACCA-3' sequence motif in regulatory regions of target genes, including a distal promoter of the HBG1 hemoglobin subunit gamma-1 gene . Involved in regulation of the developmental switch from gamma- to beta-globin, probably via direct repression of HBG1; hence indirectly repressing fetal hemoglobin (HbF) level . Involved in brain development . May play a role in hematopoiesis (By similarity). Essential factor in lymphopoiesis required for B-cell formation in fetal liver (By similarity). May function as a modulator of the transcriptional repression activity of NR2F2 (By similarity). . |
| Accessions | ENST00000643716.1 A0A2R8YCR5 ENST00000356842.9 [Q9H165-2] ENST00000642439.1 A0A2R8YHH4 ENST00000643459.1 A0A2R8YDW6 ENST00000335712.11 [Q9H165-6] A0A2R8Y7B0 ENST00000642384.2 [Q9H165-1] ENST00000647472.1 A0A0J9YYJ9 ENST00000647469.1 I3PG23 A0A2U3TZJ5 ENST00000358510.6 ENST00000643222.1 ENST00000489516.7 ENST00000409351.5 [Q9H165-8] ENST00000643004.1 ENST00000646249.1 D9YZV9 A0A0J9YY13 ENST00000631857.1 A0A2R8YDS7 D9YZW0 ENST00000489183.1 A0A2R8Y7W4 A0A0J9YXG2 ENST00000479026.2 Q9H165 A0A2R8YEK1 Q53TS1 ENST00000642180.1 A0A2R8YGT9 A0A2R8Y2E8 ENST00000359629.10 [Q9H165-3] Q53TE8 |