Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 22 studies | 44% ± 20% | |
astrocyte | 18 studies | 39% ± 21% | |
oligodendrocyte | 15 studies | 45% ± 17% | |
microglial cell | 14 studies | 37% ± 18% | |
oligodendrocyte precursor cell | 13 studies | 45% ± 18% | |
GABAergic neuron | 11 studies | 49% ± 24% | |
glutamatergic neuron | 11 studies | 50% ± 24% | |
fibroblast | 10 studies | 35% ± 13% | |
ciliated cell | 9 studies | 38% ± 25% | |
pericyte | 8 studies | 41% ± 17% | |
macrophage | 7 studies | 33% ± 12% | |
smooth muscle cell | 7 studies | 35% ± 15% | |
interneuron | 6 studies | 57% ± 21% | |
adipocyte | 6 studies | 29% ± 6% | |
endothelial cell of lymphatic vessel | 6 studies | 37% ± 13% | |
neuron | 5 studies | 45% ± 14% | |
retinal rod cell | 5 studies | 75% ± 30% | |
type I pneumocyte | 5 studies | 32% ± 5% | |
type II pneumocyte | 5 studies | 23% ± 4% | |
epithelial cell | 4 studies | 39% ± 19% | |
granule cell | 4 studies | 28% ± 3% | |
cardiac muscle cell | 4 studies | 20% ± 3% | |
mast cell | 4 studies | 24% ± 5% | |
mesothelial cell | 4 studies | 36% ± 13% | |
Mueller cell | 4 studies | 41% ± 22% | |
retinal cone cell | 4 studies | 71% ± 19% | |
club cell | 4 studies | 26% ± 7% | |
GABAergic interneuron | 3 studies | 47% ± 6% | |
glial cell | 3 studies | 34% ± 9% | |
progenitor cell | 3 studies | 34% ± 6% | |
amacrine cell | 3 studies | 34% ± 14% | |
retinal ganglion cell | 3 studies | 50% ± 22% | |
endothelial cell of vascular tree | 3 studies | 34% ± 22% | |
ependymal cell | 3 studies | 71% ± 7% | |
T cell | 3 studies | 21% ± 2% | |
alveolar macrophage | 3 studies | 23% ± 2% | |
capillary endothelial cell | 3 studies | 35% ± 15% | |
monocyte | 3 studies | 18% ± 3% | |
natural killer cell | 3 studies | 18% ± 1% | |
lymphocyte | 3 studies | 27% ± 10% | |
basal cell | 3 studies | 39% ± 19% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 788.38 | 2640 / 2642 | 100% | 9.64 | 702 / 705 |
thymus | 100% | 1864.95 | 653 / 653 | 99% | 11.42 | 599 / 605 |
prostate | 100% | 1091.47 | 245 / 245 | 98% | 5.37 | 490 / 502 |
breast | 100% | 1105.73 | 459 / 459 | 98% | 6.76 | 1091 / 1118 |
skin | 100% | 873.98 | 1801 / 1809 | 98% | 8.91 | 462 / 472 |
lung | 100% | 959.86 | 578 / 578 | 95% | 5.42 | 1101 / 1155 |
kidney | 100% | 907.55 | 89 / 89 | 95% | 6.90 | 857 / 901 |
adrenal gland | 100% | 1233.75 | 258 / 258 | 93% | 5.98 | 215 / 230 |
esophagus | 100% | 748.47 | 1442 / 1445 | 93% | 4.72 | 171 / 183 |
ovary | 100% | 1435.78 | 180 / 180 | 93% | 4.50 | 399 / 430 |
uterus | 100% | 1390.06 | 170 / 170 | 92% | 4.88 | 423 / 459 |
bladder | 100% | 987.43 | 21 / 21 | 92% | 4.42 | 463 / 504 |
pancreas | 91% | 315.72 | 297 / 328 | 98% | 5.33 | 174 / 178 |
intestine | 100% | 866.19 | 965 / 966 | 86% | 3.35 | 452 / 527 |
stomach | 99% | 576.46 | 357 / 359 | 84% | 3.44 | 241 / 286 |
liver | 87% | 308.11 | 197 / 226 | 45% | 1.47 | 181 / 406 |
spleen | 100% | 727.51 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 3.00 | 1 / 1 |
adipose | 100% | 1053.68 | 1203 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 978.65 | 1333 / 1335 | 0% | 0 | 0 / 0 |
heart | 96% | 675.84 | 827 / 861 | 0% | 0 | 0 / 0 |
muscle | 92% | 350.51 | 737 / 803 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 89% | 4.10 | 40 / 45 |
eye | 0% | 0 | 0 / 0 | 88% | 4.56 | 70 / 80 |
lymph node | 0% | 0 | 0 / 0 | 86% | 4.13 | 25 / 29 |
peripheral blood | 62% | 243.85 | 575 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0060271 | Biological process | cilium assembly |
GO_0007601 | Biological process | visual perception |
GO_0015031 | Biological process | protein transport |
GO_0061512 | Biological process | protein localization to cilium |
GO_0045444 | Biological process | fat cell differentiation |
GO_0060170 | Cellular component | ciliary membrane |
GO_0005929 | Cellular component | cilium |
GO_0000242 | Cellular component | pericentriolar material |
GO_0005829 | Cellular component | cytosol |
GO_0035869 | Cellular component | ciliary transition zone |
GO_0034464 | Cellular component | BBSome |
GO_0034451 | Cellular component | centriolar satellite |
GO_0016020 | Cellular component | membrane |
GO_0005515 | Molecular function | protein binding |
GO_0003674 | Molecular function | molecular_function |
Gene name | BBS9 |
Protein name | Protein PTHB1 (Bardet-Biedl syndrome 9 protein) (Parathyroid hormone-responsive B1 gene protein) Bardet-Biedl syndrome 9 |
Synonyms | PTHB1 |
Description | FUNCTION: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. Required for proper BBSome complex assembly and its ciliary localization. . |
Accessions | A0A5F9ZGX9 A0A5F9ZH06 ENST00000673056.1 ENST00000671952.1 ENST00000242067.11 [Q3SYG4-1] ENST00000432983.5 ENST00000671890.1 ENST00000434373.3 A0A5F9ZGY2 ENST00000672973.1 A0A5F9ZHP5 A0A5F9ZHE7 F8WCG5 ENST00000673219.1 ENST00000396127.6 [Q3SYG4-4] ENST00000433714.5 ENST00000673431.1 ENST00000350941.7 [Q3SYG4-2] ENST00000355070.6 [Q3SYG4-7] A0A5F9ZH74 Q3SYG4 ENST00000425508.6 [Q3SYG4-5] A0A5F9ZH37 C9JJ08 ENST00000673462.1 [Q3SYG4-6] A0A5F9ZH14 H7BZ69 ENST00000672717.1 [Q3SYG4-4] ENST00000671963.1 ENST00000671871.1 |