Name | Number of supported studies | Average coverage | |
---|---|---|---|
epithelial cell | 3 studies | 26% ± 13% |
Insufficient scRNA-seq data for expression of ATXN1L at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 3667.33 | 1445 / 1445 | 100% | 26.32 | 183 / 183 |
intestine | 100% | 3773.17 | 966 / 966 | 99% | 17.27 | 524 / 527 |
brain | 100% | 2164.22 | 2636 / 2642 | 100% | 22.36 | 702 / 705 |
stomach | 100% | 3079.74 | 359 / 359 | 99% | 18.11 | 284 / 286 |
lung | 100% | 3584.47 | 578 / 578 | 99% | 19.80 | 1145 / 1155 |
breast | 100% | 4145.84 | 459 / 459 | 99% | 22.65 | 1104 / 1118 |
skin | 100% | 4252.58 | 1809 / 1809 | 99% | 21.34 | 466 / 472 |
kidney | 100% | 3239.89 | 89 / 89 | 99% | 26.88 | 889 / 901 |
thymus | 100% | 3373.77 | 653 / 653 | 98% | 20.29 | 595 / 605 |
pancreas | 99% | 1982.12 | 325 / 328 | 99% | 19.12 | 176 / 178 |
bladder | 100% | 3280.71 | 21 / 21 | 97% | 15.90 | 489 / 504 |
uterus | 100% | 3824.57 | 170 / 170 | 96% | 17.72 | 441 / 459 |
adrenal gland | 100% | 2601.28 | 258 / 258 | 96% | 15.36 | 220 / 230 |
prostate | 100% | 2432.10 | 245 / 245 | 95% | 15.64 | 478 / 502 |
ovary | 100% | 3071.43 | 180 / 180 | 94% | 14.23 | 404 / 430 |
liver | 99% | 1254.34 | 223 / 226 | 81% | 8.52 | 330 / 406 |
adipose | 100% | 4442.67 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 4110.03 | 1335 / 1335 | 0% | 0 | 0 / 0 |
muscle | 100% | 2277.30 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 3017.57 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 7.83 | 1 / 1 |
heart | 97% | 1762.58 | 834 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 96% | 20.97 | 43 / 45 |
eye | 0% | 0 | 0 / 0 | 93% | 11.54 | 74 / 80 |
peripheral blood | 86% | 1951.41 | 795 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 66% | 10.60 | 19 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006366 | Biological process | transcription by RNA polymerase II |
GO_0007612 | Biological process | learning |
GO_1902035 | Biological process | positive regulation of hematopoietic stem cell proliferation |
GO_0030198 | Biological process | extracellular matrix organization |
GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
GO_0006355 | Biological process | regulation of DNA-templated transcription |
GO_0007420 | Biological process | brain development |
GO_0007613 | Biological process | memory |
GO_0048856 | Biological process | anatomical structure development |
GO_0035176 | Biological process | social behavior |
GO_0048286 | Biological process | lung alveolus development |
GO_0005730 | Cellular component | nucleolus |
GO_0005654 | Cellular component | nucleoplasm |
GO_0030425 | Cellular component | dendrite |
GO_0005634 | Cellular component | nucleus |
GO_0003677 | Molecular function | DNA binding |
GO_0031208 | Molecular function | POZ domain binding |
GO_0003723 | Molecular function | RNA binding |
GO_0005515 | Molecular function | protein binding |
Gene name | ATXN1L |
Protein name | Ataxin-1-like (Brother of ataxin-1) (Brother of ATXN1) Ataxin-1-like |
Synonyms | BOAT BOAT1 |
Description | FUNCTION: Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression . Can suppress ATXN1 cytotoxicity in spinocerebellar ataxia type 1 (SCA1). In concert with CIC and ATXN1, involved in brain development (By similarity). . |
Accessions | ENST00000683775.1 G1UI23 P0C7T5 ENST00000427980.7 |