ATP6V0E2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007035Biological processvacuolar acidification
GO_1902600Biological processproton transmembrane transport
GO_0055085Biological processtransmembrane transport
GO_0016241Biological processregulation of macroautophagy
GO_0000220Cellular componentvacuolar proton-transporting V-type ATPase, V0 domain
GO_0010008Cellular componentendosome membrane
GO_0030672Cellular componentsynaptic vesicle membrane
GO_0030665Cellular componentclathrin-coated vesicle membrane
GO_0005765Cellular componentlysosomal membrane
GO_0016020Cellular componentmembrane
GO_0030670Cellular componentphagocytic vesicle membrane
GO_0046961Molecular functionproton-transporting ATPase activity, rotational mechanism
GO_0042625Molecular functionATPase-coupled ion transmembrane transporter activity

IV. Literature review

[source]
Gene nameATP6V0E2
Protein nameV-type proton ATPase subunit e 2 (V-ATPase subunit e 2) (Lysosomal 9 kDa H(+)-transporting ATPase V0 subunit e2) (Vacuolar proton pump subunit e 2)
V-type proton ATPase subunit e 2
ATPase H+ transporting V0 subunit e2
SynonymsATP6V0E2L
C7orf32
DescriptionFUNCTION: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity). .

AccessionsENST00000471877.5 [Q8NHE4-1]
F8WDM2
ENST00000464683.5
ENST00000425642.3 [Q8NHE4-1]
E9PAS2
ENST00000479613.5 [Q8NHE4-3]
ENST00000464662.5 [Q8NHE4-1]
ENST00000456496.7 [Q8NHE4-1]
ENST00000649866.2 [Q8NHE4-1]
ENST00000421974
ENST00000606024.5 [Q8NHE4-2]
ENST00000421974.7 [Q8NHE4-2]
Q8NHE4