ARL1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006886Biological processintracellular protein transport
GO_0034067Biological processprotein localization to Golgi apparatus
GO_0042147Biological processretrograde transport, endosome to Golgi
GO_0016192Biological processvesicle-mediated transport
GO_0007030Biological processGolgi organization
GO_0009404Biological processtoxin metabolic process
GO_0005794Cellular componentGolgi apparatus
GO_0032588Cellular componenttrans-Golgi network membrane
GO_0005802Cellular componenttrans-Golgi network
GO_0000139Cellular componentGolgi membrane
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0008047Molecular functionenzyme activator activity
GO_0019904Molecular functionprotein domain specific binding
GO_0005525Molecular functionGTP binding
GO_0046872Molecular functionmetal ion binding
GO_0005515Molecular functionprotein binding
GO_1990583Molecular functionphospholipase D activator activity
GO_0003924Molecular functionGTPase activity

IV. Literature review

[source]
Gene nameARL1
Protein nameADP ribosylation factor like GTPase 1 (cDNA FLJ50309, highly similar to ADP-ribosylation factor-like protein 1)
ADP ribosylation factor like GTPase 1
ADP-ribosylation factor-like protein 1
Synonyms
DescriptionFUNCTION: GTP-binding protein that recruits several effectors, such as golgins, arfaptins and Arf-GEFs to the trans-Golgi network, and modulates their functions at the Golgi complex . Plays thereby a role in a wide range of fundamental cellular processes, including cell polarity, innate immunity, or protein secretion mediated by arfaptins, which were shown to play a role in maintaining insulin secretion from pancreatic beta cells . .

AccessionsENST00000261636.13 [P40616-1]
B4DZG7
ENST00000548070.1
P40616
F8VP63
F8VYN9
ENST00000551688.1
ENST00000551092.5
ENST00000536227.5 [P40616-2]
ENST00000551828.5 [P40616-2]
ENST00000551671.5
F8W1Z8
F8VP99
ENST00000539055.5