Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 13 studies | 31% ± 16% | |
glutamatergic neuron | 10 studies | 43% ± 25% | |
oligodendrocyte precursor cell | 10 studies | 33% ± 14% | |
microglial cell | 9 studies | 28% ± 11% | |
endothelial cell | 8 studies | 30% ± 15% | |
GABAergic neuron | 8 studies | 50% ± 21% | |
macrophage | 7 studies | 34% ± 9% | |
neuron | 6 studies | 37% ± 16% | |
interneuron | 6 studies | 52% ± 19% | |
oligodendrocyte | 6 studies | 25% ± 8% | |
retinal cone cell | 5 studies | 50% ± 20% | |
epithelial cell | 4 studies | 25% ± 12% | |
granule cell | 4 studies | 33% ± 7% | |
cardiac muscle cell | 4 studies | 21% ± 1% | |
retinal rod cell | 4 studies | 36% ± 7% | |
endothelial cell of lymphatic vessel | 4 studies | 22% ± 3% | |
fibroblast | 4 studies | 22% ± 6% | |
monocyte | 4 studies | 19% ± 3% | |
adipocyte | 4 studies | 21% ± 2% | |
GABAergic interneuron | 3 studies | 41% ± 15% | |
retinal bipolar neuron | 3 studies | 23% ± 7% | |
GABAergic amacrine cell | 3 studies | 19% ± 3% | |
amacrine cell | 3 studies | 20% ± 3% | |
rod bipolar cell | 3 studies | 33% ± 13% | |
alveolar macrophage | 3 studies | 28% ± 8% | |
myeloid cell | 3 studies | 28% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 4616.34 | 1445 / 1445 | 100% | 42.43 | 183 / 183 |
skin | 100% | 3979.94 | 1809 / 1809 | 100% | 78.93 | 472 / 472 |
breast | 100% | 4494.43 | 459 / 459 | 100% | 38.49 | 1113 / 1118 |
ovary | 100% | 5211.58 | 180 / 180 | 100% | 29.17 | 428 / 430 |
lung | 100% | 5251.17 | 578 / 578 | 99% | 28.83 | 1148 / 1155 |
stomach | 100% | 4331.63 | 359 / 359 | 99% | 30.58 | 284 / 286 |
intestine | 100% | 5683.10 | 966 / 966 | 99% | 25.67 | 523 / 527 |
brain | 99% | 5347.75 | 2620 / 2642 | 99% | 32.68 | 701 / 705 |
bladder | 100% | 5155.71 | 21 / 21 | 98% | 24.47 | 494 / 504 |
pancreas | 100% | 2461.38 | 327 / 328 | 98% | 23.69 | 175 / 178 |
uterus | 100% | 5794.51 | 170 / 170 | 98% | 25.87 | 449 / 459 |
prostate | 100% | 5346.77 | 245 / 245 | 97% | 22.35 | 487 / 502 |
adrenal gland | 100% | 5519.55 | 258 / 258 | 97% | 37.08 | 223 / 230 |
kidney | 100% | 3572.40 | 89 / 89 | 97% | 18.36 | 872 / 901 |
thymus | 100% | 6224.90 | 653 / 653 | 96% | 22.98 | 578 / 605 |
liver | 100% | 2330.31 | 225 / 226 | 89% | 18.80 | 360 / 406 |
adipose | 100% | 4687.88 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 28.72 | 80 / 80 |
spleen | 100% | 4918.27 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 15.74 | 1 / 1 |
blood vessel | 100% | 4482.27 | 1334 / 1335 | 0% | 0 | 0 / 0 |
muscle | 100% | 2824.50 | 799 / 803 | 0% | 0 | 0 / 0 |
heart | 98% | 3409.09 | 842 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 96% | 19.85 | 43 / 45 |
peripheral blood | 81% | 3175.52 | 748 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 72% | 14.14 | 21 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0030010 | Biological process | establishment of cell polarity |
GO_0007266 | Biological process | Rho protein signal transduction |
GO_0006941 | Biological process | striated muscle contraction |
GO_0030036 | Biological process | actin cytoskeleton organization |
GO_0051056 | Biological process | regulation of small GTPase mediated signal transduction |
GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
GO_0001558 | Biological process | regulation of cell growth |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0005886 | Cellular component | plasma membrane |
GO_0005737 | Cellular component | cytoplasm |
GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
GO_0005515 | Molecular function | protein binding |
GO_0005096 | Molecular function | GTPase activator activity |
GO_0001664 | Molecular function | G protein-coupled receptor binding |
Gene name | ARHGEF11 |
Protein name | Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF) ARHGEF11 |
Synonyms | KIAA0380 |
Description | FUNCTION: May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. Involved in neurotrophin-induced neurite outgrowth. . |
Accessions | ENST00000361409.2 [O15085-1] A0A2X0SFB0 ENST00000368194.8 [O15085-2] O15085 |