ARHGAP29 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	51 studies	58% ± 16%	Explore
pericyte	36 studies	40% ± 16%	Explore
endothelial cell of lymphatic vessel	28 studies	60% ± 17%	Explore
smooth muscle cell	24 studies	34% ± 17%	Explore
capillary endothelial cell	17 studies	61% ± 12%	Explore
endothelial cell of artery	16 studies	52% ± 15%	Explore
vein endothelial cell	15 studies	51% ± 17%	Explore
endothelial cell of vascular tree	15 studies	46% ± 16%	Explore
fibroblast	14 studies	30% ± 18%	Explore
type I pneumocyte	9 studies	30% ± 8%	Explore
basal cell	9 studies	38% ± 16%	Explore
epithelial cell	8 studies	36% ± 17%	Explore
adipocyte	7 studies	25% ± 6%	Explore
astrocyte	7 studies	25% ± 10%	Explore
mesothelial cell	6 studies	28% ± 13%	Explore
podocyte	5 studies	43% ± 9%	Explore
club cell	5 studies	27% ± 7%	Explore
retinal rod cell	5 studies	26% ± 5%	Explore
Mueller cell	5 studies	52% ± 16%	Explore
secretory cell	5 studies	39% ± 21%	Explore
endothelial cell of sinusoid	4 studies	42% ± 28%	Explore
GABAergic neuron	4 studies	28% ± 7%	Explore
glutamatergic neuron	4 studies	37% ± 9%	Explore
glomerular endothelial cell	4 studies	61% ± 4%	Explore
parietal epithelial cell	4 studies	60% ± 5%	Explore
kidney loop of Henle epithelial cell	4 studies	26% ± 6%	Explore
retina horizontal cell	4 studies	22% ± 2%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	36% ± 11%	Explore
luminal cell of prostate epithelium	4 studies	39% ± 11%	Explore
renal principal cell	4 studies	35% ± 4%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	23% ± 2%	Explore
ciliated cell	3 studies	20% ± 4%	Explore
abnormal cell	3 studies	49% ± 18%	Explore
myofibroblast cell	3 studies	27% ± 6%	Explore
hepatocyte	3 studies	34% ± 5%	Explore
muscle cell	3 studies	22% ± 5%	Explore
type II pneumocyte	3 studies	19% ± 3%	Explore
connective tissue cell	3 studies	27% ± 9%	Explore
interneuron	3 studies	21% ± 3%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	7 studies	21% ± 6%	Explore
eye	6 studies	26% ± 6%	Explore
kidney	5 studies	26% ± 9%	Explore
heart	5 studies	23% ± 4%	Explore
breast	4 studies	24% ± 3%	Explore
prostate	4 studies	29% ± 8%	Explore
brain	4 studies	28% ± 10%	Explore
adipose	3 studies	24% ± 6%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	11349.91	459 / 459	96%	21.25	1078 / 1118
kidney	100%	6583.19	89 / 89	96%	29.34	863 / 901
ovary	98%	3506.88	177 / 180	97%	14.08	417 / 430
prostate	100%	4046.24	244 / 245	96%	13.84	480 / 502
thymus	100%	8561.08	653 / 653	92%	17.96	556 / 605
liver	100%	2776.57	226 / 226	76%	7.07	309 / 406
lung	100%	9373.01	578 / 578	72%	7.23	837 / 1155
pancreas	77%	1308.83	251 / 328	82%	6.79	146 / 178
esophagus	85%	2506.07	1227 / 1445	70%	6.49	129 / 183
bladder	100%	2716.48	21 / 21	53%	5.01	265 / 504
uterus	99%	3576.01	168 / 170	52%	5.12	240 / 459
stomach	99%	2869.45	355 / 359	52%	3.25	149 / 286
skin	100%	5707.49	1804 / 1809	39%	2.90	186 / 472
brain	79%	2105.12	2080 / 2642	56%	3.52	392 / 705
intestine	83%	2446.93	805 / 966	40%	2.38	211 / 527
adrenal gland	53%	865.14	137 / 258	47%	2.84	109 / 230
adipose	100%	10578.04	1204 / 1204	0%	0	0 / 0
blood vessel	100%	5268.38	1335 / 1335	0%	0	0 / 0
spleen	100%	5829.71	241 / 241	0%	0	0 / 0
heart	99%	3571.43	853 / 861	0%	0	0 / 0
muscle	96%	2209.19	771 / 803	0%	0	0 / 0
tonsil	0%	0	0 / 0	36%	2.20	16 / 45
lymph node	0%	0	0 / 0	7%	0.25	2 / 29
eye	0%	0	0 / 0	1%	0.04	1 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_0007266	Biological process	Rho protein signal transduction
GO_0051056	Biological process	regulation of small GTPase mediated signal transduction
GO_0090630	Biological process	activation of GTPase activity
GO_0005737	Cellular component	cytoplasm
GO_0032991	Cellular component	protein-containing complex
GO_0005829	Cellular component	cytosol
GO_0030165	Molecular function	PDZ domain binding
GO_0046872	Molecular function	metal ion binding
GO_0005096	Molecular function	GTPase activator activity

IV. Literature review

[source]

Gene name	ARHGAP29
Protein name	Rho GTPase-activating protein 29 (Rho-type GTPase-activating protein 29) Rho GTPase-activating protein 29 (PTPL1-associated RhoGAP protein 1) (Rho-type GTPase-activating protein 29)
Synonyms	PARG1
Description	FUNCTION: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has strong activity toward RHOA, and weaker activity toward RAC1 and CDC42. May act as a specific effector of RAP2A to regulate Rho. In concert with RASIP1, suppresses RhoA signaling and dampens ROCK and MYH9 activities in endothelial cells and plays an essential role in blood vessel tubulogenesis. .
Accessions	ENST00000260526.11 [Q52LW3-1] ENST00000370217.3 [Q52LW3-2] Q52LW3 ENST00000552844.5 A0A2X0U4J5 F8VWZ8

ARHGAP29 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review