AQP1 | OmnibusX

Name	Number of supported studies	Average coverage
endothelial cell	27 studies	46% ± 22%	Explore
capillary endothelial cell	15 studies	51% ± 24%	Explore
vein endothelial cell	14 studies	55% ± 24%	Explore
endothelial cell of artery	13 studies	51% ± 26%	Explore
endothelial cell of vascular tree	11 studies	52% ± 21%	Explore
type II pneumocyte	10 studies	36% ± 13%	Explore
type I pneumocyte	8 studies	28% ± 6%	Explore
epithelial cell of proximal tubule	7 studies	27% ± 8%	Explore
mesothelial cell	6 studies	45% ± 8%	Explore
astrocyte	5 studies	34% ± 17%	Explore
pericyte	5 studies	45% ± 17%	Explore
glomerular endothelial cell	4 studies	57% ± 3%	Explore
epithelial cell	4 studies	22% ± 6%	Explore
fibroblast	4 studies	26% ± 2%	Explore
smooth muscle cell	3 studies	18% ± 1%	Explore
intestinal crypt stem cell	3 studies	31% ± 10%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
kidney	4 studies	18% ± 3%	Explore
lung	4 studies	23% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
kidney	100%	41916.36	89 / 89	87%	723.01	786 / 901
pancreas	98%	20269.10	320 / 328	88%	196.42	157 / 178
thymus	89%	20846.00	579 / 653	90%	158.42	546 / 605
breast	98%	44665.84	452 / 459	79%	119.67	888 / 1118
lung	100%	79960.60	578 / 578	72%	236.93	828 / 1155
prostate	90%	17830.83	221 / 245	77%	82.18	387 / 502
bladder	100%	26490.67	21 / 21	48%	68.37	242 / 504
esophagus	89%	46203.22	1283 / 1445	45%	61.36	82 / 183
brain	45%	8688.28	1192 / 2642	87%	619.43	610 / 705
uterus	98%	27070.57	166 / 170	30%	35.78	136 / 459
skin	67%	13486.98	1207 / 1809	49%	121.98	231 / 472
intestine	72%	12254.42	697 / 966	41%	57.64	214 / 527
stomach	43%	11656.62	156 / 359	58%	92.35	167 / 286
adipose	100%	55921.71	1201 / 1204	0%	0	0 / 0
blood vessel	99%	66998.53	1324 / 1335	0%	0	0 / 0
heart	92%	18511.85	789 / 861	0%	0	0 / 0
adrenal gland	10%	936.23	26 / 258	42%	116.91	97 / 230
muscle	46%	5260.67	372 / 803	0%	0	0 / 0
tonsil	0%	0	0 / 0	44%	33.15	20 / 45
liver	1%	96.59	3 / 226	34%	162.96	137 / 406
lymph node	0%	0	0 / 0	28%	16.80	8 / 29
ovary	16%	2783.11	28 / 180	10%	7.72	42 / 430
spleen	2%	151.28	4 / 241	0%	0	0 / 0
eye	0%	0	0 / 0	1%	0.82	1 / 80
peripheral blood	1%	57.49	5 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_0035378	Biological process	carbon dioxide transmembrane transport
GO_0048146	Biological process	positive regulation of fibroblast proliferation
GO_0033363	Biological process	secretory granule organization
GO_0042476	Biological process	odontogenesis
GO_0015793	Biological process	glycerol transmembrane transport
GO_0071260	Biological process	cellular response to mechanical stimulus
GO_0072230	Biological process	metanephric proximal straight tubule development
GO_0048593	Biological process	camera-type eye morphogenesis
GO_0072488	Biological process	ammonium transmembrane transport
GO_0050829	Biological process	defense response to Gram-negative bacterium
GO_0071805	Biological process	potassium ion transmembrane transport
GO_0071320	Biological process	cellular response to cAMP
GO_0043066	Biological process	negative regulation of apoptotic process
GO_0009992	Biological process	intracellular water homeostasis
GO_0070301	Biological process	cellular response to hydrogen peroxide
GO_0019233	Biological process	sensory perception of pain
GO_0071300	Biological process	cellular response to retinoic acid
GO_0003091	Biological process	renal water homeostasis
GO_0071549	Biological process	cellular response to dexamethasone stimulus
GO_0015670	Biological process	carbon dioxide transport
GO_0034644	Biological process	cellular response to UV
GO_0045766	Biological process	positive regulation of angiogenesis
GO_0010761	Biological process	fibroblast migration
GO_0010763	Biological process	positive regulation of fibroblast migration
GO_0006884	Biological process	cell volume homeostasis
GO_0051458	Biological process	corticotropin secretion
GO_0042060	Biological process	wound healing
GO_0030157	Biological process	pancreatic juice secretion
GO_0071474	Biological process	cellular hyperosmotic response
GO_0030185	Biological process	nitric oxide transport
GO_0043154	Biological process	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO_0019934	Biological process	cGMP-mediated signaling
GO_0072232	Biological process	metanephric proximal convoluted tubule segment 2 development
GO_0003097	Biological process	renal water transport
GO_0050891	Biological process	multicellular organismal-level water homeostasis
GO_0006833	Biological process	water transport
GO_0006972	Biological process	hyperosmotic response
GO_0030950	Biological process	establishment or maintenance of actin cytoskeleton polarity
GO_0071472	Biological process	cellular response to salt stress
GO_0033326	Biological process	cerebrospinal fluid secretion
GO_0046878	Biological process	positive regulation of saliva secretion
GO_0072220	Biological process	metanephric descending thin limb development
GO_0006813	Biological process	potassium ion transport
GO_0071288	Biological process	cellular response to mercury ion
GO_0003094	Biological process	glomerular filtration
GO_0044241	Biological process	lipid digestion
GO_0071732	Biological process	cellular response to nitric oxide
GO_0051649	Biological process	establishment of localization in cell
GO_0019725	Biological process	cellular homeostasis
GO_0070295	Biological process	renal water absorption
GO_0071280	Biological process	cellular response to copper ion
GO_0021670	Biological process	lateral ventricle development
GO_0072239	Biological process	metanephric glomerulus vasculature development
GO_0035377	Biological process	transepithelial water transport
GO_0071456	Biological process	cellular response to hypoxia
GO_0009925	Cellular component	basal plasma membrane
GO_0016323	Cellular component	basolateral plasma membrane
GO_0005634	Cellular component	nucleus
GO_0070062	Cellular component	extracellular exosome
GO_0170014	Cellular component	ankyrin-1 complex
GO_0005886	Cellular component	plasma membrane
GO_0005737	Cellular component	cytoplasm
GO_0030424	Cellular component	axon
GO_0045177	Cellular component	apical part of cell
GO_0031526	Cellular component	brush border membrane
GO_0005903	Cellular component	brush border
GO_0016324	Cellular component	apical plasma membrane
GO_0042383	Cellular component	sarcolemma
GO_0031965	Cellular component	nuclear membrane
GO_0046875	Molecular function	ephrin receptor binding
GO_0042802	Molecular function	identical protein binding
GO_0005223	Molecular function	intracellularly cGMP-activated cation channel activity
GO_0008519	Molecular function	ammonium channel activity
GO_0005267	Molecular function	potassium channel activity
GO_0035379	Molecular function	carbon dioxide transmembrane transporter activity
GO_0015079	Molecular function	potassium ion transmembrane transporter activity
GO_0015168	Molecular function	glycerol transmembrane transporter activity
GO_0005372	Molecular function	water transmembrane transporter activity
GO_0005515	Molecular function	protein binding
GO_0030184	Molecular function	nitric oxide transmembrane transporter activity
GO_0015250	Molecular function	water channel activity
GO_0022857	Molecular function	transmembrane transporter activity

Gene name	AQP1
Protein name	Aquaporin 1 splice variant 2 Aquaporin-1 (Aquaporin-CHIP) (Water channel protein for red blood cells and kidney proximal tubule) Aquaporin-1 (AQP-1) (Aquaporin-CHIP) (Urine water channel) (Water channel protein for red blood cells and kidney proximal tubule) Aquaporin 1 (Colton blood group)
Synonyms	tcag7.688 CHIP28
Description	FUNCTION: Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient . Component of the ankyrin-1 complex, a multiprotein complex involved in the stability and shape of the erythrocyte membrane . .
Accessions	ENST00000652696.1 [P29972-1] ENST00000409611.1 [P29972-3] P29972 A0A024RA31 A0A494C1U4 ENST00000651610.1 A0A494C115 Q6JSD7 A0A7L9R2Q4 ENST00000409899.5 [P29972-4] Q8TCV1 B4F4P6 ENST00000652692.1 Q6JSD8 ENST00000311813.11 [P29972-1] A0A0M7BEW0

AQP1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review