Name | Number of supported studies | Average coverage | |
---|---|---|---|
fibroblast | 20 studies | 26% ± 7% | |
plasmacytoid dendritic cell | 11 studies | 23% ± 4% | |
mast cell | 11 studies | 28% ± 11% | |
dendritic cell | 9 studies | 30% ± 10% | |
macrophage | 8 studies | 35% ± 10% | |
adipocyte | 8 studies | 30% ± 8% | |
smooth muscle cell | 8 studies | 22% ± 5% | |
endothelial cell | 7 studies | 25% ± 7% | |
myofibroblast cell | 6 studies | 18% ± 3% | |
myeloid cell | 6 studies | 25% ± 7% | |
endothelial cell of lymphatic vessel | 6 studies | 32% ± 17% | |
classical monocyte | 5 studies | 19% ± 3% | |
lymphocyte | 5 studies | 22% ± 7% | |
conventional dendritic cell | 4 studies | 22% ± 3% | |
CD4-positive, alpha-beta T cell | 4 studies | 22% ± 5% | |
hepatocyte | 4 studies | 33% ± 10% | |
connective tissue cell | 4 studies | 25% ± 6% | |
naive thymus-derived CD4-positive, alpha-beta T cell | 3 studies | 19% ± 3% | |
glial cell | 3 studies | 24% ± 6% | |
retinal cone cell | 3 studies | 21% ± 6% | |
monocyte | 3 studies | 33% ± 2% | |
pericyte | 3 studies | 22% ± 7% | |
B cell | 3 studies | 25% ± 9% | |
Schwann cell | 3 studies | 37% ± 23% | |
cardiac muscle cell | 3 studies | 18% ± 2% | |
astrocyte | 3 studies | 40% ± 17% | |
regulatory T cell | 3 studies | 22% ± 4% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
adipose | 3 studies | 26% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 9967.29 | 244 / 245 | 100% | 68.87 | 502 / 502 |
intestine | 100% | 13044.37 | 966 / 966 | 98% | 22.95 | 516 / 527 |
breast | 99% | 8108.38 | 456 / 459 | 94% | 13.58 | 1046 / 1118 |
lung | 99% | 4567.30 | 572 / 578 | 94% | 18.81 | 1080 / 1155 |
bladder | 100% | 15971.71 | 21 / 21 | 87% | 15.83 | 440 / 504 |
adrenal gland | 93% | 4334.67 | 241 / 258 | 91% | 22.32 | 209 / 230 |
esophagus | 82% | 15811.26 | 1189 / 1445 | 92% | 18.48 | 169 / 183 |
uterus | 99% | 15244.04 | 169 / 170 | 71% | 14.25 | 326 / 459 |
stomach | 75% | 8815.24 | 269 / 359 | 95% | 21.44 | 271 / 286 |
skin | 78% | 3865.94 | 1416 / 1809 | 69% | 10.66 | 325 / 472 |
liver | 66% | 1654.48 | 149 / 226 | 77% | 8.36 | 313 / 406 |
ovary | 100% | 9984.42 | 180 / 180 | 40% | 3.34 | 173 / 430 |
thymus | 77% | 1986.14 | 503 / 653 | 47% | 3.66 | 287 / 605 |
kidney | 36% | 1212.72 | 32 / 89 | 79% | 13.60 | 714 / 901 |
pancreas | 10% | 198.72 | 32 / 328 | 97% | 36.90 | 172 / 178 |
adipose | 100% | 10355.31 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 7536.76 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 86% | 8.46 | 25 / 29 |
spleen | 84% | 1948.89 | 203 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 82% | 7.34 | 37 / 45 |
heart | 80% | 2293.64 | 687 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 65% | 2346.26 | 603 / 929 | 0% | 0 | 0 / 0 |
brain | 1% | 22.23 | 30 / 2642 | 61% | 6.05 | 433 / 705 |
muscle | 42% | 1051.30 | 340 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 8% | 0.36 | 6 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0009986 | Cellular component | cell surface |
GO_0010008 | Cellular component | endosome membrane |
GO_0005576 | Cellular component | extracellular region |
GO_0005886 | Cellular component | plasma membrane |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0004888 | Molecular function | transmembrane signaling receptor activity |
GO_0005515 | Molecular function | protein binding |
GO_0046872 | Molecular function | metal ion binding |
Gene name | ANTXR2 |
Protein name | ANTXR cell adhesion molecule 2 (Anthrax toxin receptor 2, isoform CRA_c) ANTXR cell adhesion molecule 2 Anthrax toxin receptor 2 (Capillary morphogenesis gene 2 protein) (CMG-2) ANTXR2 protein Anthrax toxin receptor |
Synonyms | hCG_1818780 CMG2 |
Description | FUNCTION: Necessary for cellular interactions with laminin and the extracellular matrix. .; FUNCTION: (Microbial infection) Receptor for the protective antigen (PA) of B.anthracis . Binding of PA leads to heptamerization of the receptor-PA complex . Upon binding of the PA of B.anthracis, the complex moves to glycosphingolipid-rich lipid rafts, where it is internalized via a clathrin-dependent pathway . In the endosomal membrane, at pH under 7, the complex then rearranges and forms a pore allowing the other components of anthrax toxin to escape to the cytoplasm . . |
Accessions | A0A7P0Z4A8 J3KPY9 ENST00000681115.1 [P58335-4] ENST00000346652.10 [P58335-2] ENST00000506286.1 ENST00000449651.5 ENST00000403729.7 [P58335-4] ENST00000404191.5 A0A7P0T8H3 A0A7P0TAR4 Q32Q26 ENST00000307333.7 [P58335-1] A0A0C4DG84 ENST00000681710.1 ENST00000679571.1 ENST00000680913.1 A4FUA5 P58335 |