ACBD3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006694Biological processsteroid biosynthetic process
GO_0000139Cellular componentGolgi membrane
GO_0005794Cellular componentGolgi apparatus
GO_0016020Cellular componentmembrane
GO_0005739Cellular componentmitochondrion
GO_0000062Molecular functionfatty-acyl-CoA binding
GO_0034237Molecular functionprotein kinase A regulatory subunit binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameACBD3
Protein nameGolgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi complex-associated protein 1) (GOCAP1) (Golgi phosphoprotein 1) (GOLPH1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7) [Cleaved into: Golgi resident protein GCP60, N-terminally processed]
SynonymsGOLPH1
GOCAP1
GCP60
DescriptionFUNCTION: Involved in the maintenance of Golgi structure by interacting with giantin, affecting protein transport between the endoplasmic reticulum and Golgi . Involved in hormone-induced steroid biosynthesis in testicular Leydig cells (By similarity). Recruits PI4KB to the Golgi apparatus membrane; enhances the enzyme activity of PI4KB activity via its membrane recruitment thereby increasing the local concentration of the substrate in the vicinity of the kinase . .; FUNCTION: (Microbial infection) Plays an essential role in Aichi virus RNA replication by recruiting PI4KB at the viral replication sites. .

AccessionsQ9H3P7
ENST00000366812.6