GATOR1 complex

I. Literature review

[source]
NameGATOR1 complex
IDGO_1990130
collection_id

Cellular component

Exact synonym

IML1 complex, SEACIT complex

Description

A GTPase-activating protein (GAP) complex that regulates TORC1 signaling by interacting with the Rag GTPase. In human, the GATOR1 complex consists of DEPDC5, NPRL2, and NPRL3. In S. cerevisiae, this complex is referred to as SEACIT and contains the Iml1p, Npr2p, and Npr3p proteins.

Comment

The Rag GTPase complex corresponds to Gtr1-Gtr2 GTPase complex ; GO:1990131.

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Genes