mature conventional dendritic cell differentiation

I. Involved cell-cell interactions

[source]
Interactors
Protein name
Directionality
Classification
1CCL19-CCR7CCL19_HUMAN - CCR7_HUMANLigand-ReceptorSignaling by Chemokines

II. Literature review

[source]
Namemature conventional dendritic cell differentiation
IDGO_0097029
collection_id

Biological process

Description

The process in which antigen-activated dendritic cells acquire the specialized features of a mature conventional dendritic cell. Mature conventional dendritic cells upregulate the surface expression of MHC molecules, chemokine receptors and adhesion molecules, and increase the number of dendrites (cytoplasmic protrusions) in preparation for migration to lymphoid organs where they present antigen to T cells.

Comment

Note that immunologists typically use the word 'maturation' to refer to dendritic cells undergoing the process that GO describes as 'cell differentiation'.

External URL
Genes